Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_F05
(807 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NR19|ACSA_HUMAN Acetyl-coenzyme A synthetase, cytoplas... 365 e-100
sp|Q9VP61|ACSA_DROME Acetyl-coenzyme A synthetase (Acetate-... 362 e-100
sp|Q9QXG4|ACSA_MOUSE Acetyl-coenzyme A synthetase, cytoplas... 353 2e-97
sp|Q9HV66|ACS2_PSEAE Acetyl-coenzyme A synthetase 2 (Acetat... 310 4e-84
sp|Q8P3L1|ACSA_XANCP Acetyl-coenzyme A synthetase (Acetate-... 309 7e-84
sp|Q88DW6|ACS2_PSEPK Acetyl-coenzyme A synthetase 2 (Acetat... 309 7e-84
sp|Q885K7|ACSA_PSESM Acetyl-coenzyme A synthetase (Acetate-... 308 1e-83
sp|Q8PF09|ACSA_XANAC Acetyl-coenzyme A synthetase (Acetate-... 307 2e-83
sp|Q8EDK3|ACSA_SHEON Acetyl-coenzyme A synthetase (Acetate-... 305 7e-83
sp|Q88EH6|ACS1_PSEPK Acetyl-coenzyme A synthetase 1 (Acetat... 303 5e-82
>sp|Q9NR19|ACSA_HUMAN Acetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase)
(Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS)
(AceCS) (Acyl-CoA synthetase short-chain family member 2)
Length = 701
Score = 365 bits (936), Expect = e-100
Identities = 167/246 (67%), Positives = 194/246 (78%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W WY VVG CPIVDTFWQTETGGH++TPLPG TP+KPGSATFPFFG+ A+++E+G+
Sbjct: 447 WLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGE 506
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
E+ G EGYLVFK+PWPG+MRT+Y NH R+E TYFK+FPGYY TGDG RD+ GYY ITG
Sbjct: 507 ELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITG 566
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
RIDDMLNVSGHL+STA+VESALV H V EAA V PH VKGEC YCFVTL D F
Sbjct: 567 RIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPK 626
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNESNFGDISTLSDP 721
L EL +R KIG A PD+IQN P LPKTRSGKIMRR+LRKIA N+ + GD+ST++DP
Sbjct: 627 LTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADP 686
Query: 722 SVIESI 739
SVI +
Sbjct: 687 SVISHL 692
>sp|Q9VP61|ACSA_DROME Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS)
Length = 670
Score = 362 bits (929), Expect = e-100
Identities = 165/246 (67%), Positives = 196/246 (79%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W WY++ +G+ C IVDTFWQTETGGHVITPLPG TP+KPGSA+FPFFG++ L+DE G
Sbjct: 416 WLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPGATPMKPGSASFPFFGVKPTLLDECGI 475
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
EI G GEGYLVF +PWPGMMRTLY NH R+EDTYF +FPGYY TGDGA RD GY ITG
Sbjct: 476 EIKGEGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITG 535
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DDMLNVSGHL+STA+VES L HP+V E+A V PH VKGEC YCF+T ++N VFD+
Sbjct: 536 RVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVFDQK 595
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNESNFGDISTLSDP 721
L ++L VR +IG FA+PD IQN P LPKTRSGKIMRR+LRKIA N+ N GD STL+D
Sbjct: 596 LISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRNVGDTSTLADE 655
Query: 722 SVIESI 739
++E +
Sbjct: 656 QIVEQL 661
>sp|Q9QXG4|ACSA_MOUSE Acetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase)
(Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS)
(AceCS) (Acyl-CoA synthetase short-chain family member 2)
Length = 701
Score = 353 bits (907), Expect = 2e-97
Identities = 163/246 (66%), Positives = 189/246 (76%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W WY VVG CPIVDTFWQTETGGH++TPLPG TP+KPGSA+FPFFG+ ++E+G+
Sbjct: 447 WLWYHRVVGSQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSASFPFFGVALQSLNESGE 506
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
E+ G EGYLVFK+PWPG+MRT+Y NH R+E TYFK+FPGYY TGDG RD+ GYY ITG
Sbjct: 507 ELEGEAEGYLVFKQPWPGIMRTVYGNHTRFETTYFKKFPGYYVTGDGCRRDQDGYYWITG 566
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
RIDDMLNVSGHL+STA+VESALV H V EAA V PH VKGEC YCFVTL D F
Sbjct: 567 RIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPT 626
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNESNFGDISTLSDP 721
L EL +R KIG A PD+IQN P L K RSGKIMRR+LRKIA N+ + GD ST++DP
Sbjct: 627 LTEELKKQIREKIGPIATPDYIQNAPGLLKPRSGKIMRRVLRKIAQNDHDLGDTSTVADP 686
Query: 722 SVIESI 739
SVI +
Sbjct: 687 SVINHL 692
>sp|Q9HV66|ACS2_PSEAE Acetyl-coenzyme A synthetase 2 (Acetate--CoA ligase 2)
(Acyl-activating enzyme 2)
Length = 645
Score = 310 bits (793), Expect = 4e-84
Identities = 150/248 (60%), Positives = 183/248 (73%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W+WY++VVG+ CPI+DT+WQTETG +ITPLPG T LKPGSAT PFFG++ L+DE GK
Sbjct: 392 WEWYYQVVGEKRCPILDTWWQTETGSILITPLPGATALKPGSATRPFFGVQPVLLDEKGK 451
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
EI G G G L K WP +R++Y +H R DTYFK +PGYY +GDGA RDE GYY ITG
Sbjct: 452 EIDGAGSGVLAIKASWPSQIRSVYGDHQRMIDTYFKPYPGYYFSGDGARRDEDGYYWITG 511
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD++NVSGH I TA+VESALV H V EAA V PHDVKG+ Y FVTL E
Sbjct: 512 RVDDVINVSGHRIGTAEVESALVLHDAVAEAAVVGCPHDVKGQAIYAFVTLMAGSQPSEA 571
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNE-SNFGDISTLSD 718
L+ EL+ V +IG+FA PD +Q P+LPKTRSGKIMRRILRKIA NE + GD STL+D
Sbjct: 572 LQQELLALVGKEIGSFAKPDHLQWAPSLPKTRSGKIMRRILRKIACNELDSLGDTSTLAD 631
Query: 719 PSVIESIL 742
P V++ ++
Sbjct: 632 PGVVQGLI 639
>sp|Q8P3L1|ACSA_XANCP Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 647
Score = 309 bits (791), Expect = 7e-84
Identities = 152/248 (61%), Positives = 181/248 (72%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W+WY+EVVG S CPIVDT+WQTETGG +I+PL G LKPGSAT PFFG++ ALVD GK
Sbjct: 394 WRWYYEVVGDSRCPIVDTWWQTETGGILISPLAGAVDLKPGSATLPFFGVQPALVDAEGK 453
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
+ G EG LV WPG MRT+Y +H R+ DTYF+ +PG Y TGDG RD GYY ITG
Sbjct: 454 ILEGATEGNLVLLDSWPGQMRTVYGDHQRFIDTYFRTYPGSYFTGDGCRRDADGYYWITG 513
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD++NVSGH I TA+VESALV+HPKV EAA V PHDVKG+ Y +VTL E
Sbjct: 514 RVDDVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPHDVKGQGIYAYVTLIAGETPSEE 573
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANN-ESNFGDISTLSD 718
L EL++ VR +IG A PD +Q P LPKTRSGKIMRRILRKIA N GD STL+D
Sbjct: 574 LHKELVSWVRKEIGPIASPDHLQWAPGLPKTRSGKIMRRILRKIAENAPDQLGDTSTLAD 633
Query: 719 PSVIESIL 742
PSV++S++
Sbjct: 634 PSVVDSLV 641
>sp|Q88DW6|ACS2_PSEPK Acetyl-coenzyme A synthetase 2 (Acetate--CoA ligase 2)
(Acyl-activating enzyme 2)
Length = 644
Score = 309 bits (791), Expect = 7e-84
Identities = 152/248 (61%), Positives = 180/248 (72%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W+WYFE VGQ CPIVDT+WQTETGG ++TPLPG LKPG AT P FG++ L+DE GK
Sbjct: 391 WEWYFEEVGQKRCPIVDTWWQTETGGIMLTPLPGTQSLKPGCATQPMFGVQPVLLDEKGK 450
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
I GPG G L K WPG +R++Y +H R DTYFK PGYY TGDGA RD G Y ITG
Sbjct: 451 LIEGPGAGVLAIKASWPGQIRSVYGDHQRMVDTYFKPLPGYYFTGDGARRDADGDYWITG 510
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
RIDD++NVSGH I TA+VESALV H V EAA V PHD+KG+ Y FVT + D+
Sbjct: 511 RIDDVINVSGHRIGTAEVESALVLHDSVAEAAVVGYPHDLKGQGVYAFVTTMNGVTPDDT 570
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNE-SNFGDISTLSD 718
L+ EL+ V +IG+FA P+ IQ PALPKTRSGKIMRRILRKIA NE N GD STL+D
Sbjct: 571 LKAELLALVSKEIGSFAKPELIQWAPALPKTRSGKIMRRILRKIACNELENLGDTSTLAD 630
Query: 719 PSVIESIL 742
PSV++ ++
Sbjct: 631 PSVVQGLI 638
>sp|Q885K7|ACSA_PSESM Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 651
Score = 308 bits (789), Expect = 1e-83
Identities = 154/248 (62%), Positives = 182/248 (73%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W WY+ VG+ +CPIVDT+WQTETGG +I+PLPG T LKPGSAT PFFG+ ALVD G
Sbjct: 395 WGWYYNTVGKQNCPIVDTWWQTETGGILISPLPGATALKPGSATRPFFGVIPALVDNLGN 454
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
I G EG LV WPG RTLY +H R+ DTYFK F G Y TGDGA RDE GYY ITG
Sbjct: 455 LIEGAAEGNLVILDSWPGQSRTLYGDHDRFVDTYFKTFRGMYFTGDGARRDEDGYYWITG 514
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD+LNVSGH + TA++ESA+V HPKV EAA V +PHD+KG+ Y +VTL+ +
Sbjct: 515 RVDDVLNVSGHRMGTAEIESAMVAHPKVAEAAVVGVPHDLKGQGIYVYVTLNAGEEPSDA 574
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNESN-FGDISTLSD 718
LRTEL N VR +IG A PDFIQ P LPKTRSGKIMRRILRKIA E + GDISTL+D
Sbjct: 575 LRTELRNWVRKEIGPIASPDFIQWAPGLPKTRSGKIMRRILRKIATAEYDALGDISTLAD 634
Query: 719 PSVIESIL 742
P V++ ++
Sbjct: 635 PGVVQHLI 642
>sp|Q8PF09|ACSA_XANAC Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 647
Score = 307 bits (787), Expect = 2e-83
Identities = 151/248 (60%), Positives = 181/248 (72%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W+WY+EVVG S CPIVDT+WQTETGG +I+PL G LKPGSAT PFFG++ ALVD GK
Sbjct: 394 WRWYYEVVGDSRCPIVDTWWQTETGGILISPLAGAVDLKPGSATLPFFGVQPALVDAEGK 453
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
+ G EG LV WPG MR++Y +H R+ DTYF+ +PG Y TGDG RD GYY ITG
Sbjct: 454 ILEGATEGNLVLLDSWPGQMRSVYGDHQRFIDTYFRTYPGSYFTGDGCRRDADGYYWITG 513
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD++NVSGH I TA+VESALV+HPKV EAA V PHDVKG+ Y +VTL E
Sbjct: 514 RVDDVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPHDVKGQGIYAYVTLIAGQTPSED 573
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANN-ESNFGDISTLSD 718
L EL++ VR +IG A PD +Q P LPKTRSGKIMRRILRKIA N GD STL+D
Sbjct: 574 LHKELVSWVRKEIGPIASPDHLQWAPGLPKTRSGKIMRRILRKIAENAPDQLGDTSTLAD 633
Query: 719 PSVIESIL 742
PSV++S++
Sbjct: 634 PSVVDSLV 641
>sp|Q8EDK3|ACSA_SHEON Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 650
Score = 305 bits (782), Expect = 7e-83
Identities = 153/248 (61%), Positives = 180/248 (72%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W+WY EV+G HCPIVDT+WQTETGG +ITPLPG T KPGSAT PFFG++ ALVD G
Sbjct: 395 WRWYHEVIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGN 454
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
+ G EG LV WPG MRT+Y +H R+ TYFK F G Y TGDGA RDE GYY ITG
Sbjct: 455 ILEGATEGNLVLLDSWPGQMRTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITG 514
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD++NVSGH + TA+VESALV+H V EAA V PHD+KG+ Y +VTL+ E
Sbjct: 515 RVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEE 574
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNE-SNFGDISTLSD 718
LR EL VR +IGA A PD IQ LPKTRSGKIMRR LRKIA NE +N GD STL+D
Sbjct: 575 LRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLAD 634
Query: 719 PSVIESIL 742
P+VIE+++
Sbjct: 635 PAVIETLI 642
>sp|Q88EH6|ACS1_PSEPK Acetyl-coenzyme A synthetase 1 (Acetate--CoA ligase 1)
(Acyl-activating enzyme 1)
Length = 653
Score = 303 bits (775), Expect = 5e-82
Identities = 151/248 (60%), Positives = 179/248 (72%), Gaps = 1/248 (0%)
Frame = +2
Query: 2 WQWYFEVVGQSHCPIVDTFWQTETGGHVITPLPGCTPLKPGSATFPFFGIESALVDENGK 181
W WY++ VG+ CPIVDT+WQTETGG +I+PLPG T LKPGSAT PFFG+ ALVD G
Sbjct: 395 WNWYYKTVGKERCPIVDTWWQTETGGILISPLPGATGLKPGSATRPFFGVVPALVDNLGN 454
Query: 182 EIYGPGEGYLVFKRPWPGMMRTLYENHARYEDTYFKRFPGYYATGDGASRDEKGYYTITG 361
I G EG LV WPG R+LY +H R+ DTYFK F G Y TGDGA RDE GYY ITG
Sbjct: 455 LIDGAAEGNLVILDSWPGQSRSLYGDHDRFVDTYFKTFRGMYFTGDGARRDEDGYYWITG 514
Query: 362 RIDDMLNVSGHLISTAQVESALVNHPKVVEAAAVPIPHDVKGECCYCFVTLSDNFVFDEI 541
R+DD+LNVSGH + TA++ESA+V H KV EAA V +PHD+KG+ Y +VTL+ E
Sbjct: 515 RVDDVLNVSGHRMGTAEIESAMVAHSKVAEAAVVGVPHDIKGQGIYVYVTLNAGIEASEQ 574
Query: 542 LRTELINNVRTKIGAFAVPDFIQNVPALPKTRSGKIMRRILRKIANNESN-FGDISTLSD 718
LR EL N VR +IG A PD IQ P LPKTRSGKIMRRILRKIA E + GDISTL+D
Sbjct: 575 LRLELKNWVRKEIGPIASPDVIQWAPGLPKTRSGKIMRRILRKIATGEYDALGDISTLAD 634
Query: 719 PSVIESIL 742
P V++ ++
Sbjct: 635 PGVVQHLI 642
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,050,201
Number of Sequences: 369166
Number of extensions: 2131181
Number of successful extensions: 5747
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5248
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5516
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7666799535
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)