Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_E04
(853 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P36776|LONM_HUMAN Lon protease homolog, mitochondrial pr... 262 1e-69
sp|O44952|LONM_CAEEL Lon protease homolog, mitochondrial pr... 224 2e-58
sp|P93648|LONH2_MAIZE Lon protease homolog 2, mitochondrial... 221 2e-57
sp|Q9PK50|LON_CHLMU ATP-dependent protease La 219 6e-57
sp|O84348|LON_CHLTR ATP-dependent protease La 219 1e-56
sp|P93655|LONH2_ARATH Lon protease homolog 2, mitochondrial... 213 7e-55
sp|Q9Z9F4|LON_CHLPN ATP-dependent protease La 211 3e-54
sp|P36775|LONM_YEAST Lon protease homolog, mitochondrial pr... 197 4e-50
sp|Q09769|LONM_SCHPO Putative Lon protease homolog, mitocho... 188 2e-47
sp|Q59185|LON1_BORBU ATP-dependent protease La 184 3e-46
>sp|P36776|LONM_HUMAN Lon protease homolog, mitochondrial precursor (Lon protease-like
protein) (LONP) (LONHs)
Length = 959
Score = 262 bits (669), Expect = 1e-69
Identities = 141/255 (55%), Positives = 175/255 (68%)
Frame = +3
Query: 3 KSAFKIVNQSTDGIINVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFI 182
KSA+KIV+ + + VT ENLQDFVGKP++T +R+Y TP GVV GLAWT MGG+ LF+
Sbjct: 722 KSAYKIVSGEAESV-EVTPENLQDFVGKPVFTVERMYDVTPPGVVMGLAWTAMGGSTLFV 780
Query: 183 ETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKAN 362
ET+ +R +D K KD GS+ +TGQLG+VMKES IA+TFA F+
Sbjct: 781 ETSLRRPQDKDAKGDKD-------GSLEVTGQLGEVMKESARIAYTFARAFLMQ------ 827
Query: 363 SESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVA 542
A +L + IH+HVP+GA PKDGPSAG T+VTAL+SL+M V QN+A
Sbjct: 828 ---------HAPANDYLVTSHIHLHVPEGATPKDGPSAGCTIVTALLSLAMGRPVRQNLA 878
Query: 543 MTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSH 722
MTGEVSLTGK+LPVGGIKEK IAAKR+G+ I+LP ENKKD+ DL A I E L ++FV H
Sbjct: 879 MTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEGLEVHFVEH 938
Query: 723 YSEIFPITFPNNQFE 767
Y EIF I FP+ Q E
Sbjct: 939 YREIFDIAFPDEQAE 953
>sp|O44952|LONM_CAEEL Lon protease homolog, mitochondrial precursor
Length = 971
Score = 224 bits (572), Expect = 2e-58
Identities = 122/235 (51%), Positives = 156/235 (66%)
Frame = +3
Query: 45 INVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFIETTCKRNRDDVLKP 224
I V TENLQ FVG+P +T DR+Y TP GV+ GLAWT MGG+ L+IET KR D
Sbjct: 760 IVVCTENLQKFVGRPKFTSDRMYEVTPPGVIMGLAWTAMGGSALYIETVLKRPVDLT--- 816
Query: 225 LKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKANSESSSLQKTFTDAA 404
DK+ GS+ TG LGDVMKESV A T A G A + +
Sbjct: 817 -NDKD-----GSIETTGNLGDVMKESVRTALTVAK------GILAREQPDN--------- 855
Query: 405 RFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVAMTGEVSLTGKVLPV 584
+F A IHIHVP+GA PKDGPSAG+T+V++L+SL+++ V Q++AMTGE+SLTGKVLPV
Sbjct: 856 KFFDKAHIHIHVPEGATPKDGPSAGVTLVSSLLSLALDRPVVQDMAMTGEISLTGKVLPV 915
Query: 585 GGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSHYSEIFPITF 749
GGI+EK+IAA+R G + LP EN++D+DDLP +K +L I FVSHY E++ F
Sbjct: 916 GGIREKVIAARRVGAKRVFLPNENRRDFDDLPEFMKSELDIRFVSHYDELYEHLF 970
>sp|P93648|LONH2_MAIZE Lon protease homolog 2, mitochondrial precursor
Length = 964
Score = 221 bits (564), Expect = 2e-57
Identities = 117/252 (46%), Positives = 162/252 (64%), Gaps = 7/252 (2%)
Frame = +3
Query: 24 NQSTDGIIN-------VTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFI 182
N+ TDG + V + NL DFVGKP++ +R+Y TP GVV GLAWT MGG+ L+I
Sbjct: 735 NKGTDGAADKAIEKVVVDSSNLGDFVGKPVFQAERIYEHTPVGVVMGLAWTAMGGSTLYI 794
Query: 183 ETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKAN 362
ET K E E KG++VLTGQLGDVMKES IAHT +
Sbjct: 795 ET-------------KKVEEREGKGALVLTGQLGDVMKESAQIAHTVGRAVL-------- 833
Query: 363 SESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVA 542
L+K + F N+ +H+HVP G+ PKDGPSAG TM+T+++SL+M V +++A
Sbjct: 834 -----LEKEPDN--HFFANSKVHLHVPAGSTPKDGPSAGCTMITSMLSLAMGKPVKKDLA 886
Query: 543 MTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSH 722
MTGEV+LTG++LP+GG+KEK IAA+RS I ++I P NK+D+D+L + +KE L ++FV
Sbjct: 887 MTGEVTLTGRILPIGGVKEKTIAARRSAIKTLIFPAANKRDFDELASNVKEGLEVHFVDT 946
Query: 723 YSEIFPITFPNN 758
YSEI+ + F ++
Sbjct: 947 YSEIYDLAFQSD 958
>sp|Q9PK50|LON_CHLMU ATP-dependent protease La
Length = 819
Score = 219 bits (559), Expect = 6e-57
Identities = 116/255 (45%), Positives = 160/255 (62%), Gaps = 5/255 (1%)
Frame = +3
Query: 3 KSAFKIV-----NQSTDGIINVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGG 167
K A KIV N S +T +NLQD++GKPI++ DR Y TP GV TGLAWT +GG
Sbjct: 591 KVALKIVQNQEKNPSKKSRFTITPKNLQDYLGKPIFSSDRFYEKTPVGVATGLAWTSLGG 650
Query: 168 TVLFIETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNL 347
L+IE+ S K + LTGQ GDVMKES IA T+
Sbjct: 651 ATLYIESV-------------QVPSSSGKADMHLTGQAGDVMKESSQIAWTYL------- 690
Query: 348 GTKANSESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSV 527
S+L++ + F + +HIH+P+GA PKDGPSAGITMVT+L+SL ++ V
Sbjct: 691 -------HSALER-YAPGRPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPV 742
Query: 528 TQNVAMTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSI 707
N+ MTGE++LTG+VL +GGI+EK+IAA+RS +N +I P +N++DYD+LPA +K+ L +
Sbjct: 743 LNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNVLIFPEDNRRDYDELPAYLKKGLKV 802
Query: 708 YFVSHYSEIFPITFP 752
+FV+HY ++F I FP
Sbjct: 803 HFVTHYDDVFKIAFP 817
>sp|O84348|LON_CHLTR ATP-dependent protease La
Length = 819
Score = 219 bits (557), Expect = 1e-56
Identities = 115/255 (45%), Positives = 160/255 (62%), Gaps = 5/255 (1%)
Frame = +3
Query: 3 KSAFKIV-----NQSTDGIINVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGG 167
K A KIV N S +T +NLQD++GKP+++ DR Y TP GV TGLAWT +GG
Sbjct: 591 KVALKIVQNQEKNLSKKSRFTITPKNLQDYLGKPVFSSDRFYEKTPVGVATGLAWTSLGG 650
Query: 168 TVLFIETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNL 347
L+IE+ S K + LTGQ GDVMKES IA T+
Sbjct: 651 ATLYIESV-------------QVPSSSGKADMHLTGQAGDVMKESSQIAWTYL------- 690
Query: 348 GTKANSESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSV 527
S+L++ + F + +HIH+P+GA PKDGPSAGITMVT+L+SL ++ V
Sbjct: 691 -------HSALER-YAPGQPFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLDVPV 742
Query: 528 TQNVAMTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSI 707
N+ MTGE++LTG+VL +GGI+EK+IAA+RS +N +I P +N++DYD+LPA +K+ L +
Sbjct: 743 LNNLGMTGELTLTGRVLGIGGIREKLIAARRSKLNILIFPEDNRRDYDELPAYLKKGLKV 802
Query: 708 YFVSHYSEIFPITFP 752
+FV+HY ++F I FP
Sbjct: 803 HFVTHYDDVFKIAFP 817
>sp|P93655|LONH2_ARATH Lon protease homolog 2, mitochondrial precursor
Length = 940
Score = 213 bits (541), Expect = 7e-55
Identities = 111/235 (47%), Positives = 152/235 (64%)
Frame = +3
Query: 45 INVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFIETTCKRNRDDVLKP 224
+ + NL D+VGKP++ ++LY TP GVV GLAWT MGG+ L+IETT
Sbjct: 727 VMIDESNLADYVGKPVFHAEKLYEQTPVGVVMGLAWTSMGGSTLYIETTVV--------- 777
Query: 225 LKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKANSESSSLQKTFTDAA 404
E E KG + +TGQLGDVMKES IAHT A M L+K +
Sbjct: 778 ----EEGEGKGGLNITGQLGDVMKESAQIAHTVARKIM-------------LEKEPEN-- 818
Query: 405 RFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVAMTGEVSLTGKVLPV 584
+F N+ +H+HVP GA PKDGPSAG TM+T+L+SL+ V +++AMTGEV+LTG++LP+
Sbjct: 819 QFFANSKLHLHVPAGATPKDGPSAGCTMITSLLSLATKKPVRKDLAMTGEVTLTGRILPI 878
Query: 585 GGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSHYSEIFPITF 749
GG+KEK IAA+RS I +II P N++D+D+L +KE L+++FV Y +IF + F
Sbjct: 879 GGVKEKTIAARRSQIKTIIFPEANRRDFDELAENVKEGLNVHFVDDYGKIFELAF 933
>sp|Q9Z9F4|LON_CHLPN ATP-dependent protease La
Length = 819
Score = 211 bits (536), Expect = 3e-54
Identities = 112/255 (43%), Positives = 158/255 (61%), Gaps = 5/255 (1%)
Frame = +3
Query: 3 KSAFKIVN-----QSTDGIINVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGG 167
K A KIV +S ++++NLQ ++GKPI++ DR Y TP GV TGLAWT +GG
Sbjct: 592 KVALKIVQNQEKPKSKKITFKISSKNLQTYLGKPIFSSDRFYESTPVGVATGLAWTSLGG 651
Query: 168 TVLFIETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNL 347
L+IE+ + +K + LTGQ G+VMKES IA T+
Sbjct: 652 ATLYIESV---------------QVSSLKTDMHLTGQAGEVMKESSQIAWTYL------- 689
Query: 348 GTKANSESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSV 527
S+L + + F + +HIH+P+GA PKDGPSAGITMVT+L+SL + T V
Sbjct: 690 -------HSALHR-YAPGYTFFPKSQVHIHIPEGATPKDGPSAGITMVTSLLSLLLETPV 741
Query: 528 TQNVAMTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSI 707
N+ MTGE++LTG+VL VGGI+EK+IAA+RS +N +I P +N++DY++LPA +K L I
Sbjct: 742 VNNLGMTGEITLTGRVLGVGGIREKLIAARRSRLNILIFPEDNRRDYEELPAYLKTGLKI 801
Query: 708 YFVSHYSEIFPITFP 752
+FVSHY ++ + FP
Sbjct: 802 HFVSHYDDVLKVAFP 816
>sp|P36775|LONM_YEAST Lon protease homolog, mitochondrial precursor
Length = 1133
Score = 197 bits (500), Expect = 4e-50
Identities = 102/235 (43%), Positives = 149/235 (63%)
Frame = +3
Query: 45 INVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFIETTCKRNRDDVLKP 224
++++ +NL+D+VG P++T DRLY TP GVV GLAWT MGG L++E+ ++ + P
Sbjct: 899 VSISQKNLKDYVGPPVYTTDRLYETTPPGVVMGLAWTNMGGCSLYVESVLEQPLHNCKHP 958
Query: 225 LKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKANSESSSLQKTFTDAA 404
++ TGQLGDVMKES +A++FA +++ + F +
Sbjct: 959 TFER-----------TGQLGDVMKESSRLAYSFAKMYLA--------------QKFPEN- 992
Query: 405 RFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVAMTGEVSLTGKVLPV 584
RF A IH+H P+GA PKDGPSAG+TM T+ +SL++N S+ VAMTGE++LTGKVL +
Sbjct: 993 RFFEKASIHLHCPEGATPKDGPSAGVTMATSFLSLALNKSIDPTVAMTGELTLTGKVLRI 1052
Query: 585 GGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSHYSEIFPITF 749
GG++EK +AAKRSG +II P +N D+++LP +KE L Y++IF F
Sbjct: 1053 GGLREKAVAAKRSGAKTIIFPKDNLNDWEELPDNVKEGLEPLAADWYNDIFQKLF 1107
>sp|Q09769|LONM_SCHPO Putative Lon protease homolog, mitochondrial precursor
Length = 1067
Score = 188 bits (477), Expect = 2e-47
Identities = 103/247 (41%), Positives = 151/247 (61%)
Frame = +3
Query: 45 INVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFIETTCKRNRDDVLKP 224
I + ++L ++G PI+T RLY TP GVV GL WTPMGG +++ET K ++L
Sbjct: 830 IEIEEKDLTKYLGPPIYTSQRLYDTTPPGVVMGLGWTPMGGVSMYVETIVK----NIL-- 883
Query: 225 LKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKANSESSSLQKTFTDAA 404
S S+ TGQLGDVMKES I+++F+ +F+S K F +
Sbjct: 884 -----SSNSTPSLERTGQLGDVMKESSEISYSFSKSFLS--------------KHFPNN- 923
Query: 405 RFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVAMTGEVSLTGKVLPV 584
+F +A +H+H P+G++ KDGPSAGITM T+L+SL+++T V AMTGE++LTGK+L +
Sbjct: 924 KFFEHARLHMHCPEGSISKDGPSAGITMATSLLSLALDTPVPATTAMTGELTLTGKILRI 983
Query: 585 GGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSHYSEIFPITFPNNQF 764
GG++EK +AAK SG+ I+ P N D++ LP +KE L+ V+ Y ++F F N
Sbjct: 984 GGLREKTVAAKLSGMKEILFPKSNLADWEQLPDYVKEGLTGVPVAWYDDVFKRVFSNIDA 1043
Query: 765 EKAT*LF 785
EK L+
Sbjct: 1044 EKCNNLW 1050
>sp|Q59185|LON1_BORBU ATP-dependent protease La
Length = 806
Score = 184 bits (467), Expect = 3e-46
Identities = 100/249 (40%), Positives = 152/249 (61%)
Frame = +3
Query: 3 KSAFKIVNQSTDGIINVTTENLQDFVGKPIWTRDRLYPDTPEGVVTGLAWTPMGGTVLFI 182
K A K++ + ++ +NL+++VG P++ ++ + G+V GLAWT GG+ L I
Sbjct: 588 KVARKLIENTEVKSYQISNDNLEEYVGVPVFRKESMPNAMYSGMVMGLAWTNYGGSTLMI 647
Query: 183 ETTCKRNRDDVLKPLKDKESEEMKGSVVLTGQLGDVMKESVSIAHTFAMNFMSNLGTKAN 362
ET ++E G + LTG+LGDVMKES +IA+T+ + +L
Sbjct: 648 ETV---------------KTESKVGGIKLTGRLGDVMKESANIAYTYVNSIKGDL----- 687
Query: 363 SESSSLQKTFTDAARFLRNAPIHIHVPDGAVPKDGPSAGITMVTALISLSMNTSVTQNVA 542
S+ K+F F +N IH+H+P+GA PKDGPSAGIT+ +A ISL++N V ++A
Sbjct: 688 ----SISKSF-----FEKNI-IHLHIPEGATPKDGPSAGITIASAFISLALNKVVRPHLA 737
Query: 543 MTGEVSLTGKVLPVGGIKEKIIAAKRSGINSIILPTENKKDYDDLPAMIKEDLSIYFVSH 722
MTGE+SLTG V+ +GG+KEKIIAAKRSG+ II+P N+ D +++P IK ++ Y V +
Sbjct: 738 MTGELSLTGNVMMIGGLKEKIIAAKRSGVEHIIVPKANRVDLEEIPTNIKSGINFYLVDN 797
Query: 723 YSEIFPITF 749
E+ + F
Sbjct: 798 MREVIKLLF 806
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,368,339
Number of Sequences: 369166
Number of extensions: 2066951
Number of successful extensions: 5675
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5389
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5585
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)