Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_D23
(832 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26551|PPIB_SCHMA Peptidyl-prolyl cis-trans isomerase B ... 248 2e-65
sp|Q27774|PPIB_SCHJA Peptidyl-prolyl cis-trans isomerase B ... 242 8e-64
sp|P24367|PPIB_CHICK Peptidyl-prolyl cis-trans isomerase B ... 242 1e-63
sp|P24368|PPIB_RAT Peptidyl-prolyl cis-trans isomerase B pr... 239 5e-63
sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B ... 238 2e-62
sp|P24369|PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B ... 237 3e-62
sp|P80311|PPIB_BOVIN Peptidyl-prolyl cis-trans isomerase B ... 235 1e-61
sp|P52013|CYP5_CAEEL Peptidyl-prolyl cis-trans isomerase 5 ... 231 1e-60
sp|P52014|CYP6_CAEEL Peptidyl-prolyl cis-trans isomerase 6 ... 226 6e-59
sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C ... 219 6e-57
>sp|Q26551|PPIB_SCHMA Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin)
Length = 213
Score = 248 bits (632), Expect = 2e-65
Identities = 118/185 (63%), Positives = 138/185 (74%)
Frame = -2
Query: 657 GPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSKF 478
GPKVTDKVFFDIE+DGK + +I+IGLFGKTVPKTV NFK ++ G + DG+ +YKGS F
Sbjct: 27 GPKVTDKVFFDIEVDGKPLARIIIGLFGKTVPKTVENFKQLSIGTQLKDGRTASYKGSTF 86
Query: 477 HRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQFF 298
HRVIK FM+Q G SIYG++FPDENFKL H G+GWLSMANAGPDTNGSQFF
Sbjct: 87 HRVIKSFMIQGGDFTNHDGTGGFSIYGDRFPDENFKLRHVGAGWLSMANAGPDTNGSQFF 146
Query: 297 ITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPFAV 118
IT T WL+G+HVVFGKV+EGMN+VR IE+ T DRPV + I CG IPVE PF+V
Sbjct: 147 ITTVKTSWLDGKHVVFGKVVEGMNIVRQIESETTDSRDRPVKSIKIASCGHIPVEIPFSV 206
Query: 117 AKEAA 103
A
Sbjct: 207 TNSDA 211
>sp|Q27774|PPIB_SCHJA Peptidyl-prolyl cis-trans isomerase B precursor (PPIase B)
(Rotamase B) (Cyclophilin B) (S-cyclophilin)
Length = 213
Score = 242 bits (618), Expect = 8e-64
Identities = 115/185 (62%), Positives = 138/185 (74%)
Frame = -2
Query: 657 GPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSKF 478
GPKVT+KVFFDIE+D + +G+I+IGLFGKTVPKTV NFK ++ G DG+ YKGS F
Sbjct: 27 GPKVTEKVFFDIEVDEQPLGRIIIGLFGKTVPKTVENFKQLSIGTTLKDGRTAAYKGSTF 86
Query: 477 HRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQFF 298
HRVIK FM+Q G SIYG +FPDENFKL H G+GWLSMANAGP+TNG+QFF
Sbjct: 87 HRVIKSFMIQGGDFTNHDGTGGFSIYGERFPDENFKLKHVGAGWLSMANAGPNTNGAQFF 146
Query: 297 ITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPFAV 118
IT PWL+G+HVVFGKV+EGM+VVR IEN +T DRPV V I +CG IPV+ PF+V
Sbjct: 147 ITTTQNPWLDGKHVVFGKVVEGMSVVRQIENMQTDSRDRPVKSVKIANCGHIPVDVPFSV 206
Query: 117 AKEAA 103
+ A
Sbjct: 207 SNTDA 211
>sp|P24367|PPIB_CHICK Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP)
Length = 207
Score = 242 bits (617), Expect = 1e-63
Identities = 119/185 (64%), Positives = 140/185 (75%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
KKGPKVT KVFFD+ + ++ G++VIGLFGKTVPKTV NF ++A G K +KGS
Sbjct: 28 KKGPKVTAKVFFDLRVGEEDAGRVVIGLFGKTVPKTVENFVALATGEKG-----FGFKGS 82
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
KFHRVIKDFM+Q G SIYG++FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 83 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGDRFPDENFKLKHYGPGWVSMANAGKDTNGSQ 142
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT T WL+G+HVVFGKVLEGM+VVR +ENTKT D+P+ DV I DCG+I VE PF
Sbjct: 143 FFITTVKTAWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVTIADCGTIEVEKPF 202
Query: 123 AVAKE 109
A+AKE
Sbjct: 203 AIAKE 207
>sp|P24368|PPIB_RAT Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 239 bits (611), Expect = 5e-63
Identities = 119/185 (64%), Positives = 137/185 (74%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
KKGPKVT KV+FD +I + VG++ GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDFQIGDEPVGRVTFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
KFHRVIKDFM+Q G SIYG +FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT T WL+G+HVVFGKVLEGM+VVR +ENTKT D+P+ DV+IVDCG I VE PF
Sbjct: 144 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRDKPLKDVIIVDCGKIEVEKPF 203
Query: 123 AVAKE 109
A+AKE
Sbjct: 204 AIAKE 208
>sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 238 bits (607), Expect = 2e-62
Identities = 117/185 (63%), Positives = 137/185 (74%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
KKGPKVT KV+FD+ I ++VG+++ GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
KFHRVIKDFM+Q G SIYG +FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT T WL+G+HVVFGKVLEGM VVR +E+TKT D+P+ DV+I DCG I VE PF
Sbjct: 144 FFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPF 203
Query: 123 AVAKE 109
A+AKE
Sbjct: 204 AIAKE 208
>sp|P24369|PPIB_MOUSE Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1)
Length = 208
Score = 237 bits (605), Expect = 3e-62
Identities = 118/185 (63%), Positives = 139/185 (75%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
KKGPKVT KV+FD++I ++VG++V GLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLQIGDESVGRVVFGLFGKTVPKTVDNFVALATGEKG-----FGYKNS 83
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
KFHRVIKDFM+Q G SIYG +FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT T WL+G+HVVFGKVLEGM+VVR +E+TKT D+P+ DV+IVD G I VE PF
Sbjct: 144 FFITTVKTSWLDGKHVVFGKVLEGMDVVRKVESTKTDSRDKPLKDVIIVDSGKIEVEKPF 203
Query: 123 AVAKE 109
A+AKE
Sbjct: 204 AIAKE 208
>sp|P80311|PPIB_BOVIN Peptidyl-prolyl cis-trans isomerase B precursor (PPIase) (Rotamase)
(Cyclophilin B) (S-cyclophilin) (SCYLP)
Length = 208
Score = 235 bits (599), Expect = 1e-61
Identities = 117/185 (63%), Positives = 137/185 (74%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
KKGPKVT KV+FD+ I +++G++VIGLFGKTVPKTV NF ++A G K YK S
Sbjct: 29 KKGPKVTVKVYFDLRIGDEDIGRVVIGLFGKTVPKTVDNFVALATGEKG-----FGYKDS 83
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
KFHRVIKDFM+Q G SIYG +FPDENFKL HYG GW+SMANAG DTNGSQ
Sbjct: 84 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQ 143
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT T WL+G+HV FGKVLEGM+VVR +E+TKT D+P+ DV I DCG I VE PF
Sbjct: 144 FFITTVKTAWLDGKHVGFGKVLEGMDVVRKVESTKTDGRDKPLKDVTIADCGKIEVEKPF 203
Query: 123 AVAKE 109
A+AKE
Sbjct: 204 AIAKE 208
>sp|P52013|CYP5_CAEEL Peptidyl-prolyl cis-trans isomerase 5 precursor (PPIase) (Rotamase)
(Cyclophilin-5)
Length = 204
Score = 231 bits (590), Expect = 1e-60
Identities = 119/185 (64%), Positives = 135/185 (72%)
Frame = -2
Query: 660 KGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSK 481
KGPKVTDKV+FD+EI GK +G+IVIGLFGKTVPKT TNF +A+ K Y GSK
Sbjct: 23 KGPKVTDKVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELAKKPKGEG-----YPGSK 77
Query: 480 FHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQF 301
FHRVI DFM+Q G SIYG KF DENFKL HYG+GWLSMANAG DTNGSQF
Sbjct: 78 FHRVIADFMIQGGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANAGADTNGSQF 137
Query: 300 FITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPFA 121
FIT TPWL+GRHVVFGK+LEGM+VVR IE T+ DRP DV+I G I V+TPF+
Sbjct: 138 FITTVKTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDRPKQDVIIAASGHIAVDTPFS 197
Query: 120 VAKEA 106
V +EA
Sbjct: 198 VEREA 202
>sp|P52014|CYP6_CAEEL Peptidyl-prolyl cis-trans isomerase 6 precursor (PPIase) (Rotamase)
(Cyclophilin-6)
Length = 201
Score = 226 bits (576), Expect = 6e-59
Identities = 115/183 (62%), Positives = 135/183 (73%)
Frame = -2
Query: 660 KGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGSK 481
+GP+VTDKVFFD+EI G+ VGKIVIGLFG+ VPKTV NF +A+ +G+ Y GSK
Sbjct: 20 RGPRVTDKVFFDMEIGGRPVGKIVIGLFGEVVPKTVKNFVELAQ---RAEGE--GYVGSK 74
Query: 480 FHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQF 301
FHRVI++FM+Q G SIYG +F DENFKL HYG GWLSMANAG DTNGSQF
Sbjct: 75 FHRVIENFMIQGGDFTRGDGTGGRSIYGERFEDENFKLQHYGPGWLSMANAGEDTNGSQF 134
Query: 300 FITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPFA 121
FIT T WL+G+HVVFGK+LEGM+VVR IE T G DRP+ DVVI + G IPVE PF
Sbjct: 135 FITTAKTSWLDGKHVVFGKILEGMDVVREIEATPKGAGDRPIEDVVIANAGHIPVENPFT 194
Query: 120 VAK 112
VA+
Sbjct: 195 VAR 197
>sp|P30412|PPIC_MOUSE Peptidyl-prolyl cis-trans isomerase C (PPIase) (Rotamase)
(Cyclophilin C)
Length = 212
Score = 219 bits (559), Expect = 6e-57
Identities = 112/182 (61%), Positives = 130/182 (71%)
Frame = -2
Query: 663 KKGPKVTDKVFFDIEIDGKNVGKIVIGLFGKTVPKTVTNFKSIAEGFKTTDGKVLTYKGS 484
K+GP VTDKVFFD+ I K+VG+IVIGLFG VPKTV NF ++A G K YKGS
Sbjct: 31 KRGPSVTDKVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATGEKGYG-----YKGS 85
Query: 483 KFHRVIKDFMLQXXXXXXXXXXXGISIYGNKFPDENFKLNHYGSGWLSMANAGPDTNGSQ 304
FHRVIKDFM+Q G+SIYG FPDENFKL HYG GW+SMANAGPDTNGSQ
Sbjct: 86 IFHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQ 145
Query: 303 FFITVKDTPWLNGRHVVFGKVLEGMNVVRMIENTKTGQNDRPVSDVVIVDCGSIPVETPF 124
FFIT+ WL+G+HVVFGKVL+GM VV IE T +DRP++D IV+ G I V+TPF
Sbjct: 146 FFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHDRPLTDCTIVNSGKIDVKTPF 205
Query: 123 AV 118
V
Sbjct: 206 VV 207
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,056,035
Number of Sequences: 369166
Number of extensions: 1530977
Number of successful extensions: 4100
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3859
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3963
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8052550455
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)