Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_C22
(708 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 (Histone macr... 100 6e-21
sp|Q02874|H2AY_RAT Core histone macro-H2A.1 (Histone macroH... 98 2e-20
sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 (Histone macr... 95 2e-19
sp|Q9HGX4|H2A_AGABI Histone H2A 75 1e-13
sp|P02269|H2A_ASTRU Histone H2A 75 2e-13
sp|P17317|H2AZ_HUMAN Histone H2A.z (H2A/z) 75 2e-13
sp|P04910|H2A2_SCHPO Histone H2A-beta (H2A.2) 75 2e-13
sp|P22647|H2AZ_ONCMY Histone H2A.Z 75 2e-13
sp|P02272|H2AV_CHICK Histone H2A variant 74 3e-13
sp|P04909|H2A1_SCHPO Histone H2A-alpha (H2A.1) 74 3e-13
>sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Length = 372
Score = 99.8 bits (247), Expect = 6e-21
Identities = 80/242 (33%), Positives = 109/242 (45%), Gaps = 24/242 (9%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R RYLKK +F+++IS+GA VY A+V+EYL AEI E AGNAAR K RI PRHI+L
Sbjct: 27 RLMRYLKK---GTFKYRISVGAPVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILL 83
Query: 181 AISQDMEMNQALKHVILPSTG-RPLNLPGKPSKQNTKTELKASIIKRXXXXXXXXXXXXX 357
A++ D E+NQ LK V + S G P P +K+ +I+
Sbjct: 84 AVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGK 143
Query: 358 XXXXXXXXXXXXXXXXXXXXXXXXXSQSNS---------LDVLNERTLFLGQKLVVVQGD 510
SNS +L+ ++L LGQKL + Q D
Sbjct: 144 KGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSD 203
Query: 511 IV---EMSADAVVHPTGGSYGFGGEVGCALSNKGG-----------AAKPSIKVCEAAVS 648
I M + +VHPT ++G AL GG ++ ++V EAAVS
Sbjct: 204 ISHIGSMRVEGIVHPTTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVS 263
Query: 649 GS 654
S
Sbjct: 264 QS 265
>sp|Q02874|H2AY_RAT Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y)
(H2A/y)
Length = 371
Score = 98.2 bits (243), Expect = 2e-20
Identities = 69/214 (32%), Positives = 104/214 (48%), Gaps = 12/214 (5%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R RY+KK P +++I +GA VY A+VLEYL AEI E AGNAAR K R+ PRHI+L
Sbjct: 27 RMLRYIKKGHP---KYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILL 83
Query: 181 AISQDMEMNQALKHVILPSTGRPLNLPGK--PSKQNTKTELKASI-------IKRXXXXX 333
A++ D E+NQ LK V + S G N+ + K+ +K +L+A I K
Sbjct: 84 AVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKK 143
Query: 334 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSQSNSLDVLNERTLFLGQKLVVVQGDI 513
+ ++ VL+ ++LFLGQKL ++ +I
Sbjct: 144 PVAKKTGGKKGARKSKKQGEVSKAASADSTTEGAPTDGFTVLSTKSLFLGQKLNLIHSEI 203
Query: 514 VEMS---ADAVVHPTGGSYGFGGEVGCALSNKGG 606
++ +A+++PT ++G L KGG
Sbjct: 204 SNLAGFEVEAIINPTNADIDLKDDLGSTLEKKGG 237
>sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y)
(H2A/y)
Length = 372
Score = 94.7 bits (234), Expect = 2e-19
Identities = 69/215 (32%), Positives = 104/215 (48%), Gaps = 13/215 (6%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R RY+KK P +++I +GA VY A+VLEYL AEI E AGNAAR K R+ PRHI+L
Sbjct: 27 RMLRYIKKGHP---KYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILL 83
Query: 181 AISQDMEMNQALKHVILPSTGRPLNLPGK--PSKQNTKTELKASIIKRXXXXXXXXXXXX 354
A++ D E+NQ LK V + S G N+ + K+ +K +L+A I
Sbjct: 84 AVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKK 143
Query: 355 XXXXXXXXXXXXXXXXXXXXXXXXXXSQSNSLD--------VLNERTLFLGQKLVVVQGD 510
S ++ + VL+ ++LFLGQKL ++ +
Sbjct: 144 PVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSE 203
Query: 511 IVEMS---ADAVVHPTGGSYGFGGEVGCALSNKGG 606
I ++ +A+++PT ++G L KGG
Sbjct: 204 ISNLAGFEVEAIINPTNADIDPKDDLGNTLEKKGG 238
>sp|Q9HGX4|H2A_AGABI Histone H2A
Length = 139
Score = 75.5 bits (184), Expect = 1e-13
Identities = 46/97 (47%), Positives = 59/97 (60%), Gaps = 5/97 (5%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR LKK ++ ++ GA VY A+VLEYL AEI E AGNAAR K +RI PRH+ L
Sbjct: 35 RVHRLLKK---GNYAQRVGAGAPVYMAAVLEYLAAEILELAGNAARDNKKQRIVPRHLQL 91
Query: 181 AISQDMEMNQALKHVILPSTG-----RPLNLPGKPSK 276
AI D E+++ L +V++ G P LP K SK
Sbjct: 92 AIRNDEELHKLLGNVVISQGGVVPHIAPELLPSKSSK 128
>sp|P02269|H2A_ASTRU Histone H2A
Length = 124
Score = 75.1 bits (183), Expect = 2e-13
Identities = 44/97 (45%), Positives = 59/97 (60%), Gaps = 5/97 (5%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR+L+K ++ ++ GA VY A+V+EYL AEI E AGNAAR K RINPRH+ L
Sbjct: 28 RVHRFLRK---GNYAERVGAGAPVYLAAVMEYLAAEILELAGNAARDNKKTRINPRHLQL 84
Query: 181 AISQDMEMNQALKHVILPSTG-----RPLNLPGKPSK 276
AI D E+N+ L V + G + + LP K +K
Sbjct: 85 AIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTAK 121
>sp|P17317|H2AZ_HUMAN Histone H2A.z (H2A/z)
Length = 128
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/98 (45%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR+LK + S R + AAVY+A++LEYL AE+ E AGNA++ LKVKRI PRH+ L
Sbjct: 32 RIHRHLKSRTTSHGR--VGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQL 89
Query: 181 AISQDMEMNQALKHVILPSTGRP---LNLPGKPSKQNT 285
AI D E++ +K I P +L GK +Q T
Sbjct: 90 AIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKT 127
>sp|P04910|H2A2_SCHPO Histone H2A-beta (H2A.2)
Length = 131
Score = 74.7 bits (182), Expect = 2e-13
Identities = 46/103 (44%), Positives = 59/103 (57%), Gaps = 10/103 (9%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR L+K ++ ++ GA VY A+VLEYL AEI E AGNAAR K RI PRH+ L
Sbjct: 31 RVHRLLRK---GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQL 87
Query: 181 AISQDMEMNQALKHVILPSTGRPLNL----------PGKPSKQ 279
AI D E+N+ L HV + G N+ GKPS++
Sbjct: 88 AIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKQSGKGKPSQE 130
>sp|P22647|H2AZ_ONCMY Histone H2A.Z
Length = 128
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/98 (45%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR+LK + S R + AAVY+A++LEYL AE+ E AGNA++ LKVKRI PRH+ L
Sbjct: 32 RIHRHLKSRTTSHGR--VGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQL 89
Query: 181 AISQDMEMNQALKHVILPSTGRP---LNLPGKPSKQNT 285
AI D E++ +K I P +L GK +Q T
Sbjct: 90 AIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKT 127
>sp|P02272|H2AV_CHICK Histone H2A variant
Length = 128
Score = 74.3 bits (181), Expect = 3e-13
Identities = 45/98 (45%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR+LK + S R + AAVY+A++LEYL AE+ E AGNA++ LKVKRI PRH+ L
Sbjct: 32 RIHRHLKTRTTSHGR--VGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQL 89
Query: 181 AISQDMEMNQALKHVILPSTGRP---LNLPGKPSKQNT 285
AI D E++ +K I P +L GK +Q T
Sbjct: 90 AIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKT 127
>sp|P04909|H2A1_SCHPO Histone H2A-alpha (H2A.1)
Length = 132
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/104 (44%), Positives = 59/104 (56%), Gaps = 11/104 (10%)
Frame = +1
Query: 1 RFHRYLKKQFPSSFRFKISIGAAVYAASVLEYLVAEIAEQAGNAARILKVKRINPRHIML 180
R HR L+K ++ ++ GA VY A+VLEYL AEI E AGNAAR K RI PRH+ L
Sbjct: 31 RVHRLLRK---GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQL 87
Query: 181 AISQDMEMNQALKHVILPSTGRPLNL-----------PGKPSKQ 279
AI D E+N+ L HV + G N+ GKPS++
Sbjct: 88 AIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKTSGRTGKPSQE 131
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,947,691
Number of Sequences: 369166
Number of extensions: 1152582
Number of successful extensions: 3605
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3433
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3600
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6219306880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)