Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_002_C06-1 (470 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner m... 127 1e-29 sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane t... 125 6e-29 sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane t... 124 1e-28 sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane t... 122 4e-28 sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane t... 121 7e-28 sp|O35092|TI17A_RAT Mitochondrial import inner membrane tra... 121 7e-28 sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner m... 119 3e-27 sp|P39515|TIM17_YEAST Mitochondrial import inner membrane t... 116 2e-26 sp|O44477|TIM17_CAEEL Probable mitochondrial import inner m... 112 4e-25 sp|Q9VN97|TI17D_DROME Probable mitochondrial import inner m... 110 2e-24
>sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 1 Length = 179 Score = 127 bits (319), Expect = 1e-29 Identities = 61/138 (44%), Positives = 86/138 (62%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 GA+GGG F + GF++APSGL RL + RS ++GG+FA+WG TFS +DC+L+Y Sbjct: 24 GALGGGAFQAIKGFRNAPSGLGYRLSGGLAAVRARSGLVGGNFAVWGATFSAIDCSLVYF 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQAIVE 365 RKKEDP N+I++G TGG+LA R G + + A VG LL +IEG GI+ +S + + Sbjct: 84 RKKEDPWNAIISGATTGGILAARTGLTSMLSSALVGGALLALIEGVGIVVSHYSADSYRQ 143 Query: 366 ESMPDNNQTISHQSLGLQ 419 S + Q + L Q Sbjct: 144 VSPVERQQRYKQELLRQQ 161
>sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 B (JM3) Length = 172 Score = 125 bits (313), Expect = 6e-29 Identities = 59/116 (50%), Positives = 79/116 (68%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGGG+F + GF++AP G+ RL +A +IR+P +GGSFA+WGG FS +DC L+ Sbjct: 24 GVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAPQIGGSFAVWGGLFSTIDCGLVRL 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQ 353 R KEDP NSI +G +TG VLA R G + G A +G +LL +IEG GIL R++ Q Sbjct: 84 RGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQ 139
>sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 124 bits (310), Expect = 1e-28 Identities = 57/115 (49%), Positives = 80/115 (69%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGGG+F + GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC+++ Sbjct: 24 GTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSMIDCSMVQV 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 350 R KEDP NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 84 RGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 122 bits (306), Expect = 4e-28 Identities = 57/115 (49%), Positives = 79/115 (68%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGGG+F GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC+++ Sbjct: 24 GTIGGGIFQAFKGFRNSPVGINHRLRGSLTAIKTRAPQLGGSFAVWGGLFSTIDCSMVQI 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 350 R KEDP NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 84 RGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 B Length = 172 Score = 121 bits (304), Expect = 7e-28 Identities = 57/116 (49%), Positives = 77/116 (66%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGGG+F + GF++AP G+ R + +IR+P +GGSFA+WGG FS +DC L+ Sbjct: 24 GVIGGGVFQAIKGFRNAPVGIRHRFRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRL 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQ 353 R KEDP NSI +G +TG VLA R G + G A +G +LL +IEG GIL R++ Q Sbjct: 84 RGKEDPWNSISSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQ 139
>sp|O35092|TI17A_RAT Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 121 bits (304), Expect = 7e-28 Identities = 57/115 (49%), Positives = 78/115 (67%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGGG+F GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC ++ Sbjct: 24 GTIGGGIFQAFKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSTIDCGMVQI 83 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 350 R KEDP NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 84 RGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 3 Length = 222 Score = 119 bits (299), Expect = 3e-27 Identities = 56/107 (52%), Positives = 75/107 (70%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G IGG LF F+ GF++AP+GL +RL K+R+P + GSFA+WG TFS VDCAL++ Sbjct: 23 GTIGGSLFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPSIAGSFAVWGATFSTVDCALVHY 82 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCG 326 R++ED NSIL+G TGG+LA R G +A A VG ++L +IEG G Sbjct: 83 RQREDAWNSILSGAATGGILAARNGIRAMANSALVGCLVLAMIEGAG 129
>sp|P39515|TIM17_YEAST Mitochondrial import inner membrane translocase subunit TIM17 (Mitochondrial protein import protein 2) (Mitochondrial inner membrane protein MIM17) Length = 158 Score = 116 bits (291), Expect = 2e-26 Identities = 56/114 (49%), Positives = 79/114 (69%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 GAIGG +++ + GF+++P G +R A + K R+PVLGG+F +WGG FS DCA+ Sbjct: 25 GAIGGVVWHGIKGFRNSPLG--ERGSGAMSAIKARAPVLGGNFGVWGGLFSTFDCAVKAV 82 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFS 347 RK+EDP N+I+AG TGG LA+RGGW + A LLG+IEG G++FQR++ Sbjct: 83 RKREDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACLLGVIEGVGLMFQRYA 136
>sp|O44477|TIM17_CAEEL Probable mitochondrial import inner membrane translocase subunit Tim17 Length = 181 Score = 112 bits (280), Expect = 4e-25 Identities = 58/136 (42%), Positives = 86/136 (63%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G +GG +F G+K+A G K+L+ ++RS + G FA WGG FS +DC L+ Sbjct: 24 GLVGGSIFQAFGGYKNAAKG--KKLVGMMREVRMRSTLTGVQFAAWGGMFSTIDCCLVAI 81 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQAIVE 365 RKKEDPINSI++GG+TG +LAIR G +AG A +G+V+L +IEG G++ R+ A+++ Sbjct: 82 RKKEDPINSIVSGGLTGALLAIRSGPKVMAGSAILGSVILAMIEGVGLVTTRW-MGAMMD 140 Query: 366 ESMPDNNQTISHQSLG 413 + P +SLG Sbjct: 141 PTQPPPEALDDPRSLG 156
>sp|Q9VN97|TI17D_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 4 Length = 224 Score = 110 bits (275), Expect = 2e-24 Identities = 49/107 (45%), Positives = 73/107 (68%) Frame = +3 Query: 6 GAIGGGLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYG 185 G +GG LF ++ GF++APSGL + L ++R+P + GSFA+WG TFS VDC ++ Sbjct: 23 GTMGGSLFQYLKGFRNAPSGLRRGLHGGIESVRLRTPAIAGSFAIWGATFSTVDCVMVSY 82 Query: 186 RKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCG 326 R++ED N+I++G TGG+LA R G +A AFVG ++L ++EG G Sbjct: 83 RQREDSWNAIVSGAATGGILAARNGIRAMANSAFVGCLVLAMLEGAG 129
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,447,188 Number of Sequences: 369166 Number of extensions: 1236735 Number of successful extensions: 4079 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3770 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4037 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2733320975 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)