Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_B01
(810 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4 233 5e-61
sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (He... 230 4e-60
sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ... 230 4e-60
sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (Mm... 229 5e-60
sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HI... 213 5e-55
sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3) 212 1e-54
sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2) 210 4e-54
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 207 2e-53
sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1) 206 6e-53
sp|Q04960|DNJH_CUCSA DnaJ protein homolog (DNAJ-1) 195 1e-49
>sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4
Length = 397
Score = 233 bits (594), Expect = 5e-61
Identities = 117/232 (50%), Positives = 160/232 (68%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
T C CKG+ E IN +DRC+ C G KV+REKK++EVH++KGM DGQ+I F+GEGDQEP L
Sbjct: 176 TVCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPEL 235
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLDNRILV+ +K GEV
Sbjct: 236 EPGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIKTLDNRILVITSKAGEV 295
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
IK+ + R + +EGMP YK+P E+G LIIQF V+FPE ++L +KL +L ++LPP Q
Sbjct: 296 IKHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPPRQKVRI 355
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQC 698
D+M + E L + P+ N + + Y+ D++G G VQC
Sbjct: 356 TDDMDQVE---LKEFCPNEQN------WRQHREAYEEDEDGPQAG----VQC 394
>sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2) (HSDJ)
Length = 397
Score = 230 bits (586), Expect = 4e-60
Identities = 115/228 (50%), Positives = 155/228 (67%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
+ C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM DGQ+I F+GEGDQEPGL
Sbjct: 175 SVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGL 234
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + PG++
Sbjct: 235 EPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQI 294
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
+K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP +
Sbjct: 295 VKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEE 354
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQ 686
D M + E L +DP+ + R H Y+ DDE GG Q
Sbjct: 355 TDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPRGGVQ 393
>sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ-like protein 1)
sp|P63037|DNJA1_MOUSE DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2)
Length = 397
Score = 230 bits (586), Expect = 4e-60
Identities = 115/228 (50%), Positives = 155/228 (67%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
+ C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM DGQ+I F+GEGDQEPGL
Sbjct: 175 SVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGL 234
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + PG++
Sbjct: 235 EPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQI 294
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
+K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP +
Sbjct: 295 VKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEE 354
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQ 686
D M + E L +DP+ + R H Y+ DDE GG Q
Sbjct: 355 TDEMDQVE---LVDFDPN-----QERRRHYNGEAYE-DDEHHPRGGVQ 393
>sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (MmDjA4)
Length = 397
Score = 229 bits (585), Expect = 5e-60
Identities = 115/232 (49%), Positives = 158/232 (68%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
T C CKG+ E IN +DRC+ C G KV REKK++EVH++KGM DGQ+I F+GEGDQEP L
Sbjct: 176 TVCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPEL 235
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
+PGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLD+R+LV+ +K GEV
Sbjct: 236 DPGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEV 295
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
IK+ + + I NEGMP YK+P E+G +IIQF VVFPE +L +KL +L ++LPP Q
Sbjct: 296 IKHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVRI 355
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQC 698
D+M + E L ++P ++ + + Y+ DDE G VQC
Sbjct: 356 TDDMDQVE---LKEFNP------NEQSWRQHREAYEEDDEEPRAG----VQC 394
>sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HIRA interacting protein 4)
(Cell cycle progression restoration gene 3 protein)
(Dnj3)
Length = 412
Score = 213 bits (542), Expect = 5e-55
Identities = 111/233 (47%), Positives = 148/233 (63%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+
Sbjct: 184 SVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGV 243
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+V
Sbjct: 244 EPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKV 303
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
I+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP +
Sbjct: 304 IEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN 363
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+ + E EE L +D + + Q R DS DE VQCA
Sbjct: 364 I--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
>sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3)
Length = 412
Score = 212 bits (539), Expect = 1e-54
Identities = 111/233 (47%), Positives = 148/233 (63%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+
Sbjct: 184 SVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGV 243
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+V
Sbjct: 244 EPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKV 303
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
I+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP +
Sbjct: 304 IEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN 363
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+ + E EE L +D + + Q R DS DE VQCA
Sbjct: 364 V--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
>sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2)
Length = 412
Score = 210 bits (534), Expect = 4e-54
Identities = 110/233 (47%), Positives = 147/233 (63%)
Frame = +3
Query: 3 TTCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGL 182
+ C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+
Sbjct: 184 SVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGV 243
Query: 183 EPGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEV 362
EPGDI + ++EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+V
Sbjct: 244 EPGDIVLFVQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKV 303
Query: 363 IKNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSS 542
I+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP +
Sbjct: 304 IEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLPSRPEVPN 363
Query: 543 LDNMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+ + E EE L +D + + Q R DS DE VQCA
Sbjct: 364 V--IGETEEVELQEFDSTRGSGGGQ----RREAYNDSSDEESSSHHGPGVQCA 410
>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2
Length = 418
Score = 207 bits (528), Expect = 2e-53
Identities = 108/233 (46%), Positives = 155/233 (66%), Gaps = 2/233 (0%)
Frame = +3
Query: 9 CRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLEP 188
C CKG E+I+++DRC +C+G+KVV++KKVLEVH++KGM +GQ+I F GE D+ P
Sbjct: 191 CNECKGTGEMISDKDRCPQCKGEKVVQQKKVLEVHVEKGMQNGQKITFPGEADEAPDTVT 250
Query: 189 GDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVIK 368
GDI VL++K H F RK DL Y L L ++LCGF+ +T LDNR L++++ PGEVIK
Sbjct: 251 GDIVFVLQQKEHPKFKRKGDDLFYEHSLSLTEALCGFQFVLTHLDNRQLLIKSNPGEVIK 310
Query: 369 NLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSSLD 548
+++ I++EGMP Y+ PF +G+L I F V FP++ L D+ L S+L PS+ +S L
Sbjct: 311 PDQFKGINDEGMPMYQRPFMRGKLYIHFSVDFPDS--LTPDQCKALESVL-PSRNASRLT 367
Query: 549 NMK--EAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+M+ E EE +H D ++ + ++ + YD DDEG GGAQRVQCA
Sbjct: 368 DMEIDECEETTMH--DVNIEEEMRRKQHQQAQEAYDEDDEG--HGGAQRVQCA 416
>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1)
Length = 397
Score = 206 bits (524), Expect = 6e-53
Identities = 107/232 (46%), Positives = 149/232 (64%), Gaps = 1/232 (0%)
Frame = +3
Query: 9 CRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLEP 188
C CKG E+IN++DRC C+G+KVV+EKKVLEVH++KGM +GQ+I F GE D+ P
Sbjct: 170 CNDCKGTGEMINDKDRCPLCKGEKVVQEKKVLEVHVEKGMQNGQRITFPGEADEAPDTVT 229
Query: 189 GDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVIK 368
GDI VL++K H F RK DL Y L L ++LCGF+ +T LD R L++++ PGEV+K
Sbjct: 230 GDIVFVLQQKEHPKFQRKGDDLFYKHTLSLTEALCGFQFVLTHLDGRQLLIKSNPGEVVK 289
Query: 369 NLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSSLD 548
+++AI++EGMP Y+ PF +G+L IQF V FP++ L D+ + S+LP S S D
Sbjct: 290 PDQFKAINDEGMPMYQRPFMRGKLYIQFLVDFPDS--LTPDQCKVIESVLPRSASSQLTD 347
Query: 549 -NMKEAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+ E EE +H D ++ + ++ YD DDEG GG QRVQCA
Sbjct: 348 MEIDECEETTMH--DVNIEEEMRRKQHQHAQEAYDEDDEG--HGGGQRVQCA 395
>sp|Q04960|DNJH_CUCSA DnaJ protein homolog (DNAJ-1)
Length = 413
Score = 195 bits (496), Expect = 1e-49
Identities = 106/233 (45%), Positives = 148/233 (63%), Gaps = 2/233 (0%)
Frame = +3
Query: 9 CRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLEP 188
C CKG E IN++DRC +C+G+KVV+EKKVLEV ++KGM + Q+I F GE D+ P
Sbjct: 189 CNECKGTGETINDKDRCSQCKGEKVVQEKKVLEVIVEKGMQNAQKITFPGEADEAPDTVT 248
Query: 189 GDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVIK 368
GDI VL++K H F RK DL L LV+SLCGF+ +T LD R L++++ PGEV+K
Sbjct: 249 GDIVFVLQQKEHPKFKRKGDDLFVEHTLSLVESLCGFQFILTHLDGRQLLIKSLPGEVVK 308
Query: 369 NLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPSQFSSSLD 548
+++AI++EGMP Y+ PF +G+L I F V FP++ L ++ L +LPP + S L
Sbjct: 309 PDQFKAINDEGMPMYQRPFMKGKLYIHFSVEFPDS--LNPEQCKALEGVLPP-RTSVQLS 365
Query: 549 NMK--EAEECVLHPYDPSMANSKSQDRYHERHHVYDSDDEGGMPGGAQRVQCA 701
+M+ E EE LH N + + R + YD D++ M GGAQRVQCA
Sbjct: 366 DMELDECEETTLHD-----VNIEEEMRRKQAQEAYDEDED--MHGGAQRVQCA 411
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,761,053
Number of Sequences: 369166
Number of extensions: 1670687
Number of successful extensions: 5341
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4903
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5112
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)