Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_A05
(805 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2) 154 3e-37
sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2) 154 4e-37
sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E) 153 6e-37
sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like ... 152 8e-37
sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4) 151 2e-36
sp|O89046|COR1B_RAT Coronin-1B (Coronin-2) 150 3e-36
sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3) 149 9e-36
sp|Q920J3|CORO6_RAT Coronin-6 149 1e-35
sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57)... 134 3e-31
sp|Q21624|CORO_CAEEL Coronin-like protein cor-1 132 8e-31
>sp|Q9BR76|CO1B_HUMAN Coronin-1B (Coronin-2)
Length = 489
Score = 154 bits (389), Expect = 3e-37
Identities = 83/259 (32%), Positives = 144/259 (55%), Gaps = 1/259 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D+++ G ++ + + +IP+ G+T + ++ + + I+ WHPT
Sbjct: 88 IDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGII--AWHPTAR 145
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTD 387
N +L++ D +++W+ E+L + L+ + ++S+N+NGS
Sbjct: 146 NVLLSA----------GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
RIID R V + H+ AR ++L +G +F+TG+S + R+ ALWD +L
Sbjct: 196 KDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENL 255
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
P+ L +LD+++G L P YD D +V+YV GKGDS + +FE+ EP P I +L + S +
Sbjct: 256 EEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEP-PYIHFLNTFTSKE 314
Query: 748 PQNGVIAMPKLGVNVAANE 804
PQ G+ +MPK G+ V+ E
Sbjct: 315 PQRGMGSMPKRGLEVSKCE 333
>sp|Q9WUM3|COR1B_MOUSE Coronin-1B (Coronin-2)
Length = 484
Score = 154 bits (388), Expect = 4e-37
Identities = 83/259 (32%), Positives = 144/259 (55%), Gaps = 1/259 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D+++ G ++ + + +IP+ G+T + ++ + + I+ WHPT
Sbjct: 88 IDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIT--WHPTAR 145
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTD 387
N +L++ D +++W+ E+L + L+ + ++S+N+NGS
Sbjct: 146 NVLLSA----------GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSAC 195
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
RIID R V + H+ AR ++L +G +F+TG+S + R+ ALWD +L
Sbjct: 196 KDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENL 255
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
P+ L +LD+++G L P YD D +V+YV GKGDS + +FE+ EP P I +L + S +
Sbjct: 256 EEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEP-PYIHFLNTFTSKE 314
Query: 748 PQNGVIAMPKLGVNVAANE 804
PQ G+ +MPK G+ V+ E
Sbjct: 315 PQRGMGSMPKRGLEVSKCE 333
>sp|Q920M5|CORO6_MOUSE Coronin-6 (Clipin E)
Length = 471
Score = 153 bits (386), Expect = 6e-37
Identities = 88/259 (33%), Positives = 141/259 (54%), Gaps = 1/259 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D+++ + + + +IPD T V N + I S + WHPT
Sbjct: 87 IDWCPHNDNVIASASDDTTVMVWQIPD--YTPVRNITEPVITLEGHSKRVGILSWHPTAR 144
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTD 387
N +L++ G D +I+W+ E LL + ++ + S+ +N NGS + T
Sbjct: 145 NVLLSAGG----------DNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTC 194
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
RIID R S+ V + A H+ AR V+ +G + STG+S + R+ ALWD N+
Sbjct: 195 KDKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNF 254
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
P+ L ++D ++GVL P YD D +++Y+ GKGDS + +FE+ EP P + YL + S +
Sbjct: 255 EEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEP-PFVHYLNTFSSKE 313
Query: 748 PQNGVIAMPKLGVNVAANE 804
PQ G+ MPK G++V+ E
Sbjct: 314 PQRGMGFMPKRGLDVSKCE 332
>sp|Q9XS70|COR1B_RABIT Coronin-1B (Coroninse) (Coronin-like protein pp66)
Length = 486
Score = 152 bits (385), Expect = 8e-37
Identities = 85/259 (32%), Positives = 142/259 (54%), Gaps = 1/259 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
IEWCP +D ++ G ++ + + +IP+ G+T + ++ + + I+ WHPT
Sbjct: 88 IEWCPHNDGVIASGSEDCTVMVWQIPEDGLTSPLTEPVVVLEGHTKRVGIVT--WHPTAR 145
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSKVVCTD 387
N +L++ D +++W+ E+L + L+ + ++S+N NGS
Sbjct: 146 NVLLSA----------GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNRNGSLFCSAC 195
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
RIID R V + H+ AR ++L +G +F+TG+S + R+ ALWD +L
Sbjct: 196 KDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENL 255
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
P+ L +LD+++G L P YD D +V+YV GKGDS + +FE+ EP P I +L + S +
Sbjct: 256 EEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEP-PYIHFLNTFTSKE 314
Query: 748 PQNGVIAMPKLGVNVAANE 804
PQ GV +MPK G+ V+ E
Sbjct: 315 PQRGVGSMPKRGLEVSKCE 333
>sp|Q9ULV4|COR1C_HUMAN Coronin-1C (Coronin-3) (hCRNN4)
Length = 474
Score = 151 bits (381), Expect = 2e-36
Identities = 79/255 (30%), Positives = 142/255 (55%), Gaps = 1/255 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D ++ G ++ + + +IP+ G+T ++ + + S + WHPT
Sbjct: 86 IDWCPHNDQVIASGSEDCTVMVWQIPENGLT--LSLTEPVVILEGHSKRVGIVAWHPTAR 143
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTD 387
N +L++ D +I+W+ E L+ + +++ + ++S+N NGS +
Sbjct: 144 NVLLSA----------GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTAS 193
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
R+ID R E V ++ H+ AR ++L +G +F+TG+S + R+ ALW+ ++
Sbjct: 194 KDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNM 253
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
PI L ++D ++GVL P YD D ++IY+ GKGDS + +FE+ E P + YL + S +
Sbjct: 254 QEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE-SPYVHYLNTFSSKE 312
Query: 748 PQNGVIAMPKLGVNV 792
PQ G+ MPK G++V
Sbjct: 313 PQRGMGYMPKRGLDV 327
>sp|O89046|COR1B_RAT Coronin-1B (Coronin-2)
Length = 484
Score = 150 bits (380), Expect = 3e-36
Identities = 84/261 (32%), Positives = 145/261 (55%), Gaps = 3/261 (1%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D+++ G ++ + + +IP+ G+T + ++ + + I+ WHPT
Sbjct: 88 IDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIT--WHPTAR 145
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI-KLNNCYLTSLSFNYNGSK--VVC 381
N +L++ D +++W+ E+L + L+ + ++S+N+NGS C
Sbjct: 146 NVLLSA----------GCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTAC 195
Query: 382 TDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDEN 561
D S RIID R V + H+ AR ++L +G +F+ G+S + R+ ALWD
Sbjct: 196 KDKS--VRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPE 253
Query: 562 DLSNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQS 741
+ P+ L +LD+++G L P YD D +V+YV GKGDS + +FE+ EP P I +L + S
Sbjct: 254 NFEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEP-PYIHFLNTFTS 312
Query: 742 AKPQNGVIAMPKLGVNVAANE 804
+PQ G+ +MPK G+ V+ E
Sbjct: 313 KEPQRGMGSMPKRGLEVSKCE 333
>sp|Q9WUM4|COR1C_MOUSE Coronin-1C (Coronin-3)
Length = 474
Score = 149 bits (376), Expect = 9e-36
Identities = 78/255 (30%), Positives = 142/255 (55%), Gaps = 1/255 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D ++ G ++ + + +IP+ G+T ++ + + S + WHPT
Sbjct: 86 IDWCPHNDQVIASGSEDCTVMVWQIPENGLT--LSLTEPVVILEGHSKRVGIVAWHPTAR 143
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTD 387
N +L++ D +I+W+ E L+ + +++ + ++S++ NGS +
Sbjct: 144 NVLLSA----------GCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTAS 193
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
R+ID R E V ++ H+ AR ++L +G +F+TG+S + R+ ALW+ ++
Sbjct: 194 KDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNM 253
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
PI L ++D ++GVL P YD D ++IY+ GKGDS + +FE+ E P + YL + S +
Sbjct: 254 QEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE-SPYVHYLNTFSSKE 312
Query: 748 PQNGVIAMPKLGVNV 792
PQ G+ MPK G++V
Sbjct: 313 PQRGMGYMPKRGLDV 327
>sp|Q920J3|CORO6_RAT Coronin-6
Length = 472
Score = 149 bits (375), Expect = 1e-35
Identities = 86/259 (33%), Positives = 139/259 (53%), Gaps = 1/259 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I+WCP +D+++ + + + +IPD T V N + I S + WHPT
Sbjct: 87 IDWCPHNDNVIASPSDDTTVMVWQIPD--YTPVRNITEPVITLEGHSKRVGILSWHPTAR 144
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIK-LNNCYLTSLSFNYNGSKVVCTD 387
N +L++ G D +I+W+ E LL + ++ + S+ +N NGS + T
Sbjct: 145 NVLLSAGG----------DNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTC 194
Query: 388 NSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDENDL 567
RIID R S+ V + H+ R V+ + G IF+TG++ + RE LWD N+
Sbjct: 195 KDKTLRIIDPRKSQVVAERFAAHEGMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNF 254
Query: 568 SNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSAK 747
P+ L ++D ++GVL P YD D +++Y+ GKGDS + +FE+ EP P + YL + S +
Sbjct: 255 EEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP-PFVHYLNTFSSKE 313
Query: 748 PQNGVIAMPKLGVNVAANE 804
PQ G+ MPK G++V+ E
Sbjct: 314 PQRGMGFMPKRGLDVSKCE 332
>sp|Q92176|COR1A_BOVIN Coronin-1A (Coronin-like protein p57) (Coronin-like protein A)
(CLIPINA) (Tryptophan aspartate-containing coat protein)
(TACO)
Length = 461
Score = 134 bits (337), Expect = 3e-31
Identities = 76/256 (29%), Positives = 135/256 (52%), Gaps = 2/256 (0%)
Frame = +1
Query: 31 IEWCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHPTVG 210
I WCP +D+++ G ++ + + IPDGG+T + ++ + + I+ WHPT
Sbjct: 87 IAWCPHNDNVIASGSEDCSVMVWEIPDGGLTLPLREPVVTLEGHTKRVGIV--AWHPTAQ 144
Query: 211 NAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEI--KLNNCYLTSLSFNYNGSKVVCT 384
N +L++ D +++WD +L + ++ + S+ ++ +G+ + +
Sbjct: 145 NVLLSA----------GCDNVILVWDVGTGVAVLTLGSDVHPDTIYSVDWSRDGALICTS 194
Query: 385 DNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDEND 564
RII+ R V ++ H+ R V++ +G I +TG+S + R+ ALWD
Sbjct: 195 CRDKRVRIIEPRKGTIVAEKDRPHEGTRPVRAVFVSDGKILTTGFSRMSERQVALWDTKH 254
Query: 565 LSNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQSA 744
L P+ L +LD +SGVL P +D D N++Y+ GKGDS + +FE+ E P + YL + S
Sbjct: 255 LEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE-APFLHYLSMFSSK 313
Query: 745 KPQNGVIAMPKLGVNV 792
+ Q G+ MPK G+ V
Sbjct: 314 ESQRGMGYMPKRGLEV 329
>sp|Q21624|CORO_CAEEL Coronin-like protein cor-1
Length = 605
Score = 132 bits (333), Expect = 8e-31
Identities = 80/261 (30%), Positives = 134/261 (51%), Gaps = 2/261 (0%)
Frame = +1
Query: 28 CIE--WCPRDDDLLLIGQQNGEINLIRIPDGGVTEVINTDDSEIKWNCESGSILNAVWHP 201
C+E W P +D+++ ++ + IPD G+ N + ++ + WHP
Sbjct: 82 CLEVAWSPFNDNVIASCSEDTTCKVWVIPDRGLNR--NLSEPAVELTGHQKRVNTIAWHP 139
Query: 202 TVGNAVLTSCGSKFAGAGSSADTHLILWDTVKTEKLLEIKLNNCYLTSLSFNYNGSKVVC 381
N +LT+ G + +W+ E LLEI + + S++FN++GS+ V
Sbjct: 140 VANNVLLTAGGENV----------MFMWNVGTGEALLEISGHPDQIWSINFNFDGSQFVT 189
Query: 382 TDNSHITRIIDLRSSEPVLQEAMLHKKARRQNTVYLKNGLIFSTGYSSTTIREYALWDEN 561
T RI+D + E V+ E M H+ + Q +++K+GLI STG++ + R YAL
Sbjct: 190 TCKDKKIRILDSHTGE-VVHEGMGHEGVKPQRAIFVKDGLILSTGFTKRSERLYALRAPE 248
Query: 562 DLSNPIELIDLDANSGVLYPIYDADINVIYVWGKGDSIMSFFEVVYEPKPTIQYLCCYQS 741
DLS PI +LD ++GV++P YD D ++Y+ GKGD + ++E V P + Y+ Y +
Sbjct: 249 DLSTPIVEEELDTSNGVVFPFYDEDSGLVYLVGKGDCAIRYYE-VNNDAPYVHYINTYTT 307
Query: 742 AKPQNGVIAMPKLGVNVAANE 804
+PQ V K G++ NE
Sbjct: 308 NEPQRAVGFQSKRGMSSEENE 328
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,513,451
Number of Sequences: 369166
Number of extensions: 2004980
Number of successful extensions: 5042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4820
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4984
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)