Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_A01
(824 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01241|NF70_LOLPE 70 kDa neurofilament protein (NF70) 117 4e-26
sp|Q01240|NF60_LOLPE 60 kDa neurofilament protein (NF60) 117 4e-26
sp|P90901|IFA1_CAEEL Intermediate filament protein ifa-1 (I... 109 8e-24
sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (I... 107 3e-23
sp|P31732|OV71_ONCVO Muscle cell intermediate filament prot... 105 1e-22
sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) 105 2e-22
sp|Q17107|AV71_ACAVI Muscle cell intermediate filament prot... 101 3e-21
sp|P90900|IFA4_CAEEL Intermediate filament protein ifa-4 (I... 99 1e-20
sp|Q19289|IFB1_CAEEL Intermediate filament protein ifb-1 (I... 98 2e-20
sp|Q21065|IFA3_CAEEL Intermediate filament protein ifa-3 (I... 97 7e-20
>sp|Q01241|NF70_LOLPE 70 kDa neurofilament protein (NF70)
Length = 615
Score = 117 bits (293), Expect = 4e-26
Identities = 64/143 (44%), Positives = 88/143 (61%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDIQ EY+ K ++ ++EA Y L++QE RT T+ N+E T KEEN+++KS + +R+
Sbjct: 307 IRDIQQEYDAKCDQMRGDIEAYYNLKVQEFRTGATKQNMEVTRNKEENTKLKSNMTEIRN 366
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
R+ADLE +NA+ E + + EE R EL+ + L ELQ L+D
Sbjct: 367 RLADLEARNAQLERTNQDLLRDLEEKDRQNELESCQYKEEITKLRGEMESILKELQDLMD 426
Query: 361 AKLGLELEIAAYAKLLEFEESRV 429
KL LELEIAAY KLLE EESRV
Sbjct: 427 IKLSLELEIAAYRKLLEGEESRV 449
>sp|Q01240|NF60_LOLPE 60 kDa neurofilament protein (NF60)
Length = 511
Score = 117 bits (293), Expect = 4e-26
Identities = 64/143 (44%), Positives = 88/143 (61%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDIQ EY+ K ++ ++EA Y L++QE RT T+ N+E T KEEN+++KS + +R+
Sbjct: 307 IRDIQQEYDAKCDQMRGDIEAYYNLKVQEFRTGATKQNMEVTRNKEENTKLKSNMTEIRN 366
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
R+ADLE +NA+ E + + EE R EL+ + L ELQ L+D
Sbjct: 367 RLADLEARNAQLERTNQDLLRDLEEKDRQNELESCQYKEEITKLRGEMESILKELQDLMD 426
Query: 361 AKLGLELEIAAYAKLLEFEESRV 429
KL LELEIAAY KLLE EESRV
Sbjct: 427 IKLSLELEIAAYRKLLEGEESRV 449
>sp|P90901|IFA1_CAEEL Intermediate filament protein ifa-1 (Intermediate filament protein
A1) (IF-A1) (Cel IF A1)
Length = 575
Score = 109 bits (273), Expect = 8e-24
Identities = 77/268 (28%), Positives = 119/268 (44%), Gaps = 1/268 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ + + +ME+ Y L++QEI+T R N+E + KEE R+++Q+ +R
Sbjct: 280 IRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRG 339
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ADLE +N+ E + + E+ QRS E L A + ELQ LLD
Sbjct: 340 KLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLD 399
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EIA Y K+LE EE+R ++
Sbjct: 400 TKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTE--------------- 444
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
T R + R F+R+ KGN+SI E G FI+L+N
Sbjct: 445 --------------------TMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNT 484
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYTI 801
K E++ +KR I+G + YT+
Sbjct: 485 HRAKDEAIGEWKLKRRIDGKRENV-YTL 511
>sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (Intermediate filament protein
A2) (IF-A2) (Cel IF A2)
Length = 581
Score = 107 bits (268), Expect = 3e-23
Identities = 79/275 (28%), Positives = 119/275 (43%), Gaps = 1/275 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ ++G + +ME+ Y L++QEI T R N E + KEE R+++Q +R
Sbjct: 282 MRDIRAEYDQIMNGNRNDMESWYQLRVQEINTQSNRQNAENNYQKEEVKRLRNQTSELRQ 341
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
+++DLE +N E + + E+ QRS E L A + ELQ LLD
Sbjct: 342 KLSDLESRNLLLEKQIEDLNYQLEDDQRSYEAALNDKDAQIRKLREECQALMVELQMLLD 401
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ E+ Y ++LE N+EGN +
Sbjct: 402 TKQTLDGELKVYRQMLE-------GNSEGNGL---------------------------- 426
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
T R S R ++R+ KGN++I ET G F+ILEN
Sbjct: 427 RQLVEKVVRTSAINEEADTETMRVVKGEHSSRTSYQRSAKGNVAIKETSPEGKFVILENT 486
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYTISSKVTLN 822
K E L +KR I+G +I +T S L+
Sbjct: 487 HRAKEEPLGDWKLKRKIDG-KREIVFTFPSDYILH 520
>sp|P31732|OV71_ONCVO Muscle cell intermediate filament protein OV71
Length = 432
Score = 105 bits (263), Expect = 1e-22
Identities = 79/267 (29%), Positives = 120/267 (44%), Gaps = 1/267 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ + + +ME+ Y L++QEI+T TR N+E + KEE R++ Q+ +R
Sbjct: 135 IRDIRAEYDQICNMNRTDMESWYKLKVQEIQTQSTRQNLEQGYAKEEVKRLRVQLSDLRG 194
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ADLE +N+ E + + E+ QRS E L A + ELQ LLD
Sbjct: 195 KLADLEGRNSLLEKQMQELNYQLEDDQRSYEAALNDRDAQIRKMREECQALMMELQMLLD 254
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EIA Y K+LE EE+R ++
Sbjct: 255 TKQTLDAEIAIYRKMLEGEENRAGLRQLVEQVVK-------------------------- 288
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
+ + ET S F+R+ KGN+SI + G FI+LEN
Sbjct: 289 -----THGLSEIGETESIRVLKGETASRTS----FQRSAKGNVSIQDASSDGKFILLENT 339
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYT 798
+K E + +KR I+G +I YT
Sbjct: 340 HRSKEEPIGEWRLKRKIDG-KREIVYT 365
>sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B)
Length = 589
Score = 105 bits (261), Expect = 2e-22
Identities = 78/274 (28%), Positives = 120/274 (43%), Gaps = 1/274 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ KQ+ME+ Y L++ E++ S R N+E+++ +EE R++ I +R
Sbjct: 291 IRDIKDEYDYIAKQGKQDMESWYKLKVSEVQGSANRANMESSYQREEVKRMRDNIGDLRG 350
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ DLE +NA E + + + QR E L + ELQ+LLD
Sbjct: 351 KLGDLEAKNALLEKEVQNLNYQLNDDQRQYEAALNDRDATLRRMREECQTLVAELQALLD 410
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EIA Y K+LE EESRV ++
Sbjct: 411 TKQMLDAEIAIYRKMLEGEESRVGLRQMVEQVVKTHSLQQQEDTD--------------- 455
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
+ R S + F+R+ KGN++I+E D G FI LEN
Sbjct: 456 --------------------STRNVRGEVSTKTTFQRSAKGNVTISECDPNGKFITLENT 495
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYTISSKVTL 819
+K E+L +KR ++ N +I YTI L
Sbjct: 496 HRSKDENLGEHRLKRKLD-NRREIVYTIPPNTVL 528
>sp|Q17107|AV71_ACAVI Muscle cell intermediate filament protein AV71
Length = 394
Score = 101 bits (251), Expect = 3e-21
Identities = 78/274 (28%), Positives = 120/274 (43%), Gaps = 1/274 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ + + +ME+ Y L++QEI+T TR N+E + KEE R++ Q+ +R
Sbjct: 97 IRDIRAEYDQICNINRTDMESWYKLKVQEIQTQSTRQNLEQGYAKEEVKRLRVQLSELRG 156
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ADLE +N+ E + E+ QRS E L A + ELQ LLD
Sbjct: 157 KLADLEGRNSLLEKQTQELNYQLEDDQRSYEAALNDRDAQIRKMREECQALMMELQMLLD 216
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EIA Y K+LE EE+R ++
Sbjct: 217 TKQTLDAEIAIYRKMLEGEENRAGLRQLVEQVVK-------------------------- 250
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
+ + ET S F+R+ KGN+SI + G +I+ EN
Sbjct: 251 -----THSLTEIGETESIRVLKGETASRTS----FQRSAKGNVSIQDAASDGKYILSENT 301
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYTISSKVTL 819
+K E + +KR I+G +I YT + L
Sbjct: 302 HRSKEEPIGEWRLKRKIDG-KREIVYTFPTNFVL 334
>sp|P90900|IFA4_CAEEL Intermediate filament protein ifa-4 (Intermediate filament protein
A4) (IF-A4) (Cel IF A4)
Length = 575
Score = 99.0 bits (245), Expect = 1e-20
Identities = 70/273 (25%), Positives = 123/273 (45%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+R+I++EY++ + + ++E+ Y L++QEI T +R+ +E + +EE R+++ + MR
Sbjct: 281 IREIRSEYDHVSNTTRTDIESWYKLKVQEIHTQNSRNCLEQNYAREEVKRLRTTLGDMRG 340
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ADLE +N E + + EE RS E L + ELQ L+D
Sbjct: 341 KMADLEGRNLLLEKQIEDLNYQMEEDMRSYEQSLNDKDTSINKLRDESKILMVELQMLID 400
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EI Y K+L+ EE+R ++
Sbjct: 401 TKQTLDAEIVIYRKMLDGEENRAGLRQLVEQVVK-------------------------- 434
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
+ + ETT + S + R+ KGNI+I E + +G +I+LENI
Sbjct: 435 -----TTSIHQTKEIESLRVLKGETTSHSS----YSRSAKGNIAIQEAEPSGKYIVLENI 485
Query: 721 GTKVESLEGMTIKRAIEGNSNQISYTISSKVTL 819
+ E++ ++R I G +I +T + TL
Sbjct: 486 SRRDENIGDWKLRRKIAG-KREIVFTFpreFTL 517
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 37 SGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRSRIADLEMQNAEY 216
S + M G IR S+TR+ E + E N R+ S I+ +R LE QN +
Sbjct: 46 SNLTSGMSPFGGHAASAIRESRTREKKEMS---ELNDRLASYIEKVRF----LEAQNRKM 98
Query: 217 EHNLNMIRGNYEETQRSLEL 276
E +LN++RG + S+++
Sbjct: 99 EKDLNLLRGKWGHDSTSVKV 118
>sp|Q19289|IFB1_CAEEL Intermediate filament protein ifb-1 (Intermediate filament protein
B1) (IF-B1) (Cel IF B1)
Length = 589
Score = 98.2 bits (243), Expect = 2e-20
Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 8/281 (2%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ KQ+ME+ Y L++ E++ S R N+E+T+ ++E R++ I +R
Sbjct: 291 IRDIKDEYDIIAKQGKQDMESWYKLKVSEVQGSANRANMESTYQRDEVKRMRDNIGDLRG 350
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
++ DLE +N+ E + + + QR E L + ELQ+LLD
Sbjct: 351 KLGDLENKNSLLEKEVQNLNYQLTDDQRQYEAALNDRDATLRRMREECQTLVAELQALLD 410
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ EIA Y K+LE EE+RV +
Sbjct: 411 TKQMLDAEIAIYRKMLEGEETRVGLTQMVEQAVK-------------------------- 444
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQ-------SKRMKFRRTTKGNISIAETDLTGS 699
+ ++E TD S + F+R+ KGN++I+E D G
Sbjct: 445 ----------------THSLQQQENTDSTRSVRGEVSTKTTFQRSAKGNVTISECDPNGK 488
Query: 700 FIILENI-GTKVESLEGMTIKRAIEGNSNQISYTISSKVTL 819
FI LEN K E++ I+R ++G +I Y+I + V +
Sbjct: 489 FIKLENSHRNKDENVGEHKIRRKLDGR-REIVYSIPANVVI 528
>sp|Q21065|IFA3_CAEEL Intermediate filament protein ifa-3 (Intermediate filament protein
A3) (IF-A3) (Cel IF A3)
Length = 581
Score = 96.7 bits (239), Expect = 7e-20
Identities = 76/275 (27%), Positives = 115/275 (41%), Gaps = 1/275 (0%)
Frame = +1
Query: 1 LRDIQTEYENKLSGIKQEMEASYGLQMQEIRTSKTRDNVETTHYKEENSRIKSQIQSMRS 180
+RDI+ EY+ ++G + ++E+ +++QEI T R N E H ++E R+ SQ+ ++S
Sbjct: 282 IRDIRAEYDRFMAGNRNDLESWSQIRVQEINTQTNRQNAEINHKRDEVKRLHSQVSELKS 341
Query: 181 RIADLEMQNAEYEHNLNMIRGNYEETQRSLELKLMSXXXXXXXXXXXXSAALTELQSLLD 360
+ A+L +N E L + E+ QRS E L A L ELQ LLD
Sbjct: 342 KHAELAARNGLLEKQLEDLNYQLEDDQRSYEAALNDKDAQVRKLREECQALLVELQMLLD 401
Query: 361 AKLGLELEIAAYAKLLEFEESRVNSNTEGNMIISQFXXXXXXXXXXXXXXXXXXXXXXXX 540
K L+ E+ Y ++LE N+E N +
Sbjct: 402 TKQTLDGELKVYRRMLE-------GNSEENGL---------------------------- 426
Query: 541 XXXXXXXXXXXXXXXXXXXMTERETTDYQSKRMKFRRTTKGNISIAETDLTGSFIILENI 720
T R S R ++R+ KGN+SI E G F+ILEN
Sbjct: 427 RQLVEKVVRTSAINEEVDTETMRVVKGEHSSRTSYQRSAKGNVSIKEVSPEGKFVILENT 486
Query: 721 -GTKVESLEGMTIKRAIEGNSNQISYTISSKVTLN 822
K E L +KR I+G +I +T S L+
Sbjct: 487 HRDKEEPLGDWKLKRKIDG-KREIVFTFPSDYILH 520
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.309 0.124 0.314
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,271,693
Number of Sequences: 369166
Number of extensions: 851491
Number of successful extensions: 2628
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2293
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2507
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)