Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_N20
(882 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BJ64|CHDH_MOUSE Choline dehydrogenase, mitochondrial p... 217 4e-56
sp|Q7MF12|BETA_VIBVY Choline dehydrogenase (CHD) (CDH) 211 2e-54
sp|Q8D3K2|BETA_VIBVU Choline dehydrogenase (CHD) (CDH) 211 2e-54
sp|Q8NE62|CHDH_HUMAN Choline dehydrogenase, mitochondrial p... 206 9e-53
sp|Q8UH55|BETA_AGRT5 Choline dehydrogenase (CHD) (CDH) 199 6e-51
sp|P54223|BETA_RHIME Choline dehydrogenase (CHD) (CDH) 195 1e-49
sp|Q8YFY2|BETA_BRUME Choline dehydrogenase (CHD) (CDH) 186 7e-47
sp|Q8G1Z8|BETA_BRUSU Choline dehydrogenase (CHD) (CDH) 184 3e-46
sp|P17444|BETA_ECOLI Choline dehydrogenase (CHD) (CDH) 183 6e-46
sp|Q8X6C6|BETA_ECO57 Choline dehydrogenase (CHD) (CDH) 182 1e-45
>sp|Q8BJ64|CHDH_MOUSE Choline dehydrogenase, mitochondrial precursor (CHD) (CDH)
Length = 596
Score = 217 bits (552), Expect = 4e-56
Identities = 103/189 (54%), Positives = 136/189 (71%), Gaps = 7/189 (3%)
Frame = +2
Query: 278 KKNYDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSD---NDRIIQMPLNLPLAMGS- 445
K Y +V+VGAGSAGCVLA+RL+ D V LLEAGP D + +Q +++P A+ S
Sbjct: 40 KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSN 99
Query: 446 ---DKYNWYYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEG 616
DKYNWYY ++ Q +++RV+Y PRG+V GGSSS+N ++Y+RGH DY+RW EGAEG
Sbjct: 100 LCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEG 159
Query: 617 WSYASSLPYFKKAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDDF 796
W YA LPYF+KA+ ELG + YRGGDGPL+V R K N LH+ +++A QAGY T+D
Sbjct: 160 WDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDM 219
Query: 797 NGYKQEGFG 823
NG++QEGFG
Sbjct: 220 NGFQQEGFG 228
>sp|Q7MF12|BETA_VIBVY Choline dehydrogenase (CHD) (CDH)
Length = 560
Score = 211 bits (537), Expect = 2e-54
Identities = 102/184 (55%), Positives = 134/184 (72%), Gaps = 2/184 (1%)
Frame = +2
Query: 278 KKNYDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYN 457
+++YDY+IVGAGSAGCVLA+RLS +V LLEAG SD IQMP L M S+KY
Sbjct: 2 QQHYDYIIVGAGSAGCVLADRLSESGDHSVLLLEAGGSDKSIFIQMPTALSYPMNSEKYA 61
Query: 458 WYYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSL 637
W + + A++ L+ R ++CPRGKVLGGSSSING++Y+RGH D+D WE +GA+GW+Y + L
Sbjct: 62 WQFETDAEADLDGRRLHCPRGKVLGGSSSINGMVYVRGHACDFDEWEEQGAKGWNYQACL 121
Query: 638 PYFKKAENCELGKSQYRGGDGPLYVIR-NKVN-QVLHETWIKAGVQAGYSHTDDFNGYKQ 811
PYF++AEN G+ +YRGGDGPL NK+ L+ +I AG +AGY T D+NGY+Q
Sbjct: 122 PYFRRAENWIDGEDEYRGGDGPLSTCAGNKMTLNPLYRAFIDAGKEAGYPETSDYNGYQQ 181
Query: 812 EGFG 823
EGFG
Sbjct: 182 EGFG 185
>sp|Q8D3K2|BETA_VIBVU Choline dehydrogenase (CHD) (CDH)
Length = 560
Score = 211 bits (537), Expect = 2e-54
Identities = 102/184 (55%), Positives = 134/184 (72%), Gaps = 2/184 (1%)
Frame = +2
Query: 278 KKNYDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYN 457
+++YDY+IVGAGSAGCVLA+RLS +V LLEAG SD IQMP L M S+KY
Sbjct: 2 QQHYDYIIVGAGSAGCVLADRLSESGDHSVLLLEAGGSDKSIFIQMPTALSYPMNSEKYA 61
Query: 458 WYYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSL 637
W + + A++ L+ R ++CPRGKVLGGSSSING++Y+RGH D+D WE +GA+GW+Y + L
Sbjct: 62 WQFETDAEADLDGRRLHCPRGKVLGGSSSINGMVYVRGHACDFDEWEEQGAKGWNYQACL 121
Query: 638 PYFKKAENCELGKSQYRGGDGPLYVIR-NKVN-QVLHETWIKAGVQAGYSHTDDFNGYKQ 811
PYF++AEN G+ +YRGGDGPL NK+ L+ +I AG +AGY T D+NGY+Q
Sbjct: 122 PYFRRAENWIDGEDEYRGGDGPLSTCAGNKMTLNPLYRAFIDAGKEAGYPETSDYNGYQQ 181
Query: 812 EGFG 823
EGFG
Sbjct: 182 EGFG 185
>sp|Q8NE62|CHDH_HUMAN Choline dehydrogenase, mitochondrial precursor (CHD) (CDH)
Length = 594
Score = 206 bits (523), Expect = 9e-53
Identities = 102/190 (53%), Positives = 130/190 (68%), Gaps = 7/190 (3%)
Frame = +2
Query: 275 SKKNYDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSD----NDRI---IQMPLNLPL 433
S+ Y YV+VGAGSAGCVLA RL+ D V LLEAGP D + R+ I MP L
Sbjct: 37 SRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVRAGSKRLSWKIHMPAALVA 96
Query: 434 AMGSDKYNWYYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAE 613
+ D+YNW Y ++ Q L+ RV+Y PRG+V GGSSS+N ++Y+RGH DY+RW+ +GA
Sbjct: 97 NLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGAR 156
Query: 614 GWSYASSLPYFKKAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDD 793
GW YA LPYF+KA+ ELG S+YRG DGPL V R K N LH +++A QAGY T+D
Sbjct: 157 GWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTED 216
Query: 794 FNGYKQEGFG 823
NG++QEGFG
Sbjct: 217 MNGFQQEGFG 226
>sp|Q8UH55|BETA_AGRT5 Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 199 bits (507), Expect = 6e-51
Identities = 98/178 (55%), Positives = 126/178 (70%)
Frame = +2
Query: 290 DYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYNWYYL 469
DYVIVG+GSAG +A RLS D + +V ++EAG SD IQMP L M +YNW YL
Sbjct: 4 DYVIVGSGSAGSAIAYRLSEDGRYSVIVIEAGGSDFGPFIQMPAALAWPMSMKRYNWGYL 63
Query: 470 SKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSLPYFK 649
S+ + L+NR I PRGKV+GGSSSING++Y+RGH D++RWE GA+GW+YA LPYFK
Sbjct: 64 SEPEPNLDNRRITAPRGKVIGGSSSINGLVYVRGHAEDFNRWEELGAQGWAYADVLPYFK 123
Query: 650 KAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDDFNGYKQEGFG 823
+ E+ G+ +RG DGPL+V R V+ L +I+AG QAG+ TDD+NG KQEGFG
Sbjct: 124 RMEHSHGGEEGWRGTDGPLHVQRGPVSNPLFHAFIQAGAQAGFELTDDYNGSKQEGFG 181
Score = 30.4 bits (67), Expect = 6.8
Identities = 11/24 (45%), Positives = 17/24 (70%)
Frame = +3
Query: 810 KKDLGHFDTTVHNGVRWSSSKAYL 881
++ G + T+HNG RWS++ AYL
Sbjct: 177 QEGFGLMEQTIHNGRRWSAANAYL 200
>sp|P54223|BETA_RHIME Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 195 bits (496), Expect = 1e-49
Identities = 95/178 (53%), Positives = 125/178 (70%)
Frame = +2
Query: 290 DYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYNWYYL 469
D+VI+G+GSAG LA RLS D + +V +LE G SD IQMP L M ++YNW YL
Sbjct: 4 DFVIIGSGSAGSALAYRLSEDGRNSVIVLEFGGSDVGPFIQMPAALAWPMSMNRYNWGYL 63
Query: 470 SKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSLPYFK 649
S+ + LNNR I PRGKV+GGSSSING++Y+RGH D++RWE GA+GW+YA LPY+K
Sbjct: 64 SEPEPNLNNRRITAPRGKVIGGSSSINGMVYVRGHSEDFNRWEELGAQGWAYADVLPYYK 123
Query: 650 KAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDDFNGYKQEGFG 823
+ E+ G+ +RG DGPL+V R V L +I+AG +AG+ T+D+NG KQEGFG
Sbjct: 124 RMEHSHGGEEGWRGTDGPLHVQRGPVKNPLFHAFIEAGKEAGFEVTEDYNGSKQEGFG 181
>sp|Q8YFY2|BETA_BRUME Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 186 bits (472), Expect = 7e-47
Identities = 88/178 (49%), Positives = 120/178 (67%)
Frame = +2
Query: 290 DYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYNWYYL 469
D+VI+G+GSAG +A RLS D + +V ++E G D +IQMP L M + Y+W +
Sbjct: 4 DFVIIGSGSAGSAMAYRLSEDGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFS 63
Query: 470 SKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSLPYFK 649
S+ + + R + PRGKVLGGSSSING++Y+RGH D+D W GA GW+YA LPYFK
Sbjct: 64 SEPEPHIRGRSLVTPRGKVLGGSSSINGMVYVRGHACDFDHWSQSGARGWAYADVLPYFK 123
Query: 650 KAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDDFNGYKQEGFG 823
+ EN + G+ +RG +GPLYV R K + L +++AG QAG+ TDD+NG KQEGFG
Sbjct: 124 RMENSQGGQEGWRGTNGPLYVQRGKRDNPLFHAFVEAGHQAGFEVTDDYNGEKQEGFG 181
Score = 30.8 bits (68), Expect = 5.2
Identities = 11/24 (45%), Positives = 17/24 (70%)
Frame = +3
Query: 810 KKDLGHFDTTVHNGVRWSSSKAYL 881
++ G + T+HNG RWS++ AYL
Sbjct: 177 QEGFGPMEQTIHNGRRWSAANAYL 200
>sp|Q8G1Z8|BETA_BRUSU Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 184 bits (467), Expect = 3e-46
Identities = 87/178 (48%), Positives = 120/178 (67%)
Frame = +2
Query: 290 DYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDNDRIIQMPLNLPLAMGSDKYNWYYL 469
D+VI+G+GSAG +A RLS + + +V ++E G D +IQMP L M + Y+W +
Sbjct: 4 DFVIIGSGSAGSAMAYRLSENGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFS 63
Query: 470 SKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETEGAEGWSYASSLPYFK 649
S+ + + R + PRGKVLGGSSSING++Y+RGH D+D W GA GW+YA LPYFK
Sbjct: 64 SEPEPHIGGRSLVTPRGKVLGGSSSINGMVYVRGHACDFDHWSQSGARGWAYADVLPYFK 123
Query: 650 KAENCELGKSQYRGGDGPLYVIRNKVNQVLHETWIKAGVQAGYSHTDDFNGYKQEGFG 823
+ EN + G+ +RG +GPLYV R K + L +++AG QAG+ TDD+NG KQEGFG
Sbjct: 124 RMENSQGGQEGWRGTNGPLYVQRGKRDNPLFHAFVEAGHQAGFEVTDDYNGEKQEGFG 181
Score = 30.8 bits (68), Expect = 5.2
Identities = 11/24 (45%), Positives = 17/24 (70%)
Frame = +3
Query: 810 KKDLGHFDTTVHNGVRWSSSKAYL 881
++ G + T+HNG RWS++ AYL
Sbjct: 177 QEGFGPMEQTIHNGRRWSAANAYL 200
>sp|P17444|BETA_ECOLI Choline dehydrogenase (CHD) (CDH)
Length = 556
Score = 183 bits (464), Expect = 6e-46
Identities = 96/183 (52%), Positives = 121/183 (66%), Gaps = 4/183 (2%)
Frame = +2
Query: 287 YDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDN--DRIIQMPLNLPLAMGSDKYNW 460
+DY+I+GAGSAG VLA RL+ D T+V LLEAG D D QMP L + +YNW
Sbjct: 3 FDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNW 62
Query: 461 YYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETE-GAEGWSYASSL 637
Y ++ + +NNR + C RGK LGGSS ING+ Y+RG+ LD D W E G E WSY L
Sbjct: 63 AYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCL 122
Query: 638 PYFKKAENCELGKSQYRGGDGPLYVIRNKVN-QVLHETWIKAGVQAGYSHTDDFNGYKQE 814
PY++KAE ++G++ Y GGDGP+ V +K L E I+AGVQAGY TDD NGY+QE
Sbjct: 123 PYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQE 182
Query: 815 GFG 823
GFG
Sbjct: 183 GFG 185
>sp|Q8X6C6|BETA_ECO57 Choline dehydrogenase (CHD) (CDH)
Length = 562
Score = 182 bits (461), Expect = 1e-45
Identities = 95/183 (51%), Positives = 121/183 (66%), Gaps = 4/183 (2%)
Frame = +2
Query: 287 YDYVIVGAGSAGCVLANRLSADKKTTVNLLEAGPSDN--DRIIQMPLNLPLAMGSDKYNW 460
+DY+I+GAGSAG VLA RL+ D T+V LLEAG D D QMP L + +YNW
Sbjct: 3 FDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNW 62
Query: 461 YYLSKAQSQLNNRVIYCPRGKVLGGSSSINGVIYMRGHPLDYDRWETE-GAEGWSYASSL 637
Y ++ + +NNR + C RGK LGGSS ING+ Y+RG+ +D D W E G E WSY L
Sbjct: 63 AYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDLDNWAKEPGLENWSYLDCL 122
Query: 638 PYFKKAENCELGKSQYRGGDGPLYVIRNKVN-QVLHETWIKAGVQAGYSHTDDFNGYKQE 814
PY++KAE ++G++ Y GGDGP+ V +K L E I+AGVQAGY TDD NGY+QE
Sbjct: 123 PYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQE 182
Query: 815 GFG 823
GFG
Sbjct: 183 GFG 185
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,417,286
Number of Sequences: 369166
Number of extensions: 1935501
Number of successful extensions: 4488
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4284
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4409
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8790245790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)