Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_N15
(405 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial... 119 3e-27
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial... 118 4e-27
sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial... 118 4e-27
sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial p... 118 4e-27
sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial... 117 9e-27
sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial... 117 1e-26
sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RAL... 113 1e-25
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RAL... 107 1e-23
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH... 107 1e-23
sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RAL... 107 1e-23
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDH1)
(ALDH-E2)
Length = 500
Score = 119 bits (297), Expect = 3e-27
Identities = 54/78 (69%), Positives = 67/78 (85%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 423 SKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGL 482
Query: 182 NNYSEVKMVTIKVPSKSS 235
Y+EVK VTIKVP K+S
Sbjct: 483 QAYTEVKTVTIKVPQKNS 500
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDHI)
(ALDH-E2)
Length = 500
Score = 118 bits (296), Expect = 4e-27
Identities = 54/78 (69%), Positives = 67/78 (85%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 423 SKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGNGRELGEYGL 482
Query: 182 NNYSEVKMVTIKVPSKSS 235
Y+EVK VTIKVP K+S
Sbjct: 483 QAYTEVKTVTIKVPQKNS 500
>sp|P47738|ALDH2_MOUSE Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(AHD-M1) (ALDHI) (ALDH-E2)
Length = 519
Score = 118 bits (296), Expect = 4e-27
Identities = 53/78 (67%), Positives = 67/78 (85%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 442 SKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGL 501
Query: 182 NNYSEVKMVTIKVPSKSS 235
Y+EVK VT+KVP K+S
Sbjct: 502 QAYTEVKTVTVKVPQKNS 519
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDH1) (ALDH-E2)
Length = 519
Score = 118 bits (296), Expect = 4e-27
Identities = 53/78 (67%), Positives = 67/78 (85%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 442 SKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGL 501
Query: 182 NNYSEVKMVTIKVPSKSS 235
Y+EVK VT+KVP K+S
Sbjct: 502 QAYTEVKTVTVKVPQKNS 519
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDHI) (ALDH-E2)
Length = 517
Score = 117 bits (293), Expect = 9e-27
Identities = 52/76 (68%), Positives = 65/76 (85%)
Frame = +2
Query: 8 YGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGLNN 187
YGLAA+VFTKD++K+ ++ Q+L+AGTVW+NCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 442 YGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQA 501
Query: 188 YSEVKMVTIKVPSKSS 235
Y+EVK VT+KVP K+S
Sbjct: 502 YTEVKTVTVKVPQKNS 517
>sp|P20000|ALDH2_BOVIN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDHI) (ALDH-E2)
Length = 520
Score = 117 bits (292), Expect = 1e-26
Identities = 51/78 (65%), Positives = 67/78 (85%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
++YGLAA+VFTKD++K+ ++ Q+L+AGTVW+NCYD F A +PFGGYK SG GRELGEYGL
Sbjct: 443 SKYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGL 502
Query: 182 NNYSEVKMVTIKVPSKSS 235
Y+EVK VT++VP K+S
Sbjct: 503 QAYTEVKTVTVRVPQKNS 520
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 509
Score = 113 bits (283), Expect = 1e-25
Identities = 51/76 (67%), Positives = 62/76 (81%)
Frame = +2
Query: 8 YGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGLNN 187
YGLAA+VFTKDI+K++ +L+AGTVW+NCY AF A PFGG+K SG GRELGEYGL
Sbjct: 434 YGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQE 493
Query: 188 YSEVKMVTIKVPSKSS 235
Y+EVK VTIK+P K+S
Sbjct: 494 YTEVKTVTIKIPQKNS 509
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 107 bits (266), Expect = 1e-23
Identities = 45/78 (57%), Positives = 64/78 (82%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
+++GL A+VFT DI K++ + +++AGTVWINCY+A +A +PFGG+K SG GRE+GE+GL
Sbjct: 422 SDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 481
Query: 182 NNYSEVKMVTIKVPSKSS 235
YSEVK VT+K+P K+S
Sbjct: 482 REYSEVKTVTVKIPQKNS 499
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 107 bits (266), Expect = 1e-23
Identities = 45/78 (57%), Positives = 64/78 (82%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
+++GL A+VFT DI K++ + +++AGTVWINCY+A +A +PFGG+K SG GRE+GE+GL
Sbjct: 422 SDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 481
Query: 182 NNYSEVKMVTIKVPSKSS 235
YSEVK VT+K+P K+S
Sbjct: 482 REYSEVKTVTVKIPQKNS 499
>sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 107 bits (266), Expect = 1e-23
Identities = 45/78 (57%), Positives = 64/78 (82%)
Frame = +2
Query: 2 NEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFDAAAPFGGYKASGVGRELGEYGL 181
+++GL A+VFT DI K++ + +++AGTVWINCY+A +A +PFGG+K SG GRE+GE+GL
Sbjct: 422 SDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGL 481
Query: 182 NNYSEVKMVTIKVPSKSS 235
YSEVK VT+K+P K+S
Sbjct: 482 REYSEVKTVTVKIPQKNS 499
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,263,532
Number of Sequences: 369166
Number of extensions: 810902
Number of successful extensions: 2434
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2386
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2420
length of database: 68,354,980
effective HSP length: 98
effective length of database: 50,250,950
effective search space used: 1809034200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)