Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_M14
(323 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29598|UROK_RAT Urokinase-type plasminogen activator pre... 50 1e-06
sp|Q15661|TRYB1_HUMAN Tryptase beta-1 precursor (Tryptase 1... 49 4e-06
sp|P20231|TRYB2_HUMAN Tryptase beta-2 precursor (Tryptase 2... 49 4e-06
sp|P50343|MCPT6_RAT Mast cell protease 6 precursor (rMCP-6)... 49 4e-06
sp|P00749|UROK_HUMAN Urokinase-type plasminogen activator p... 49 5e-06
sp|P15157|TRYA_HUMAN Alpha-tryptase precursor (Tryptase 1) 49 5e-06
sp|O18783|PLMN_MACEU Plasminogen precursor [Contains: Plasm... 48 6e-06
sp|P06868|PLMN_BOVIN Plasminogen precursor [Contains: Plasm... 48 8e-06
sp|P18291|NKP1_RAT Natural killer cell protease 1 precursor... 47 1e-05
sp|P16227|UROK_PAPCY Urokinase-type plasminogen activator p... 47 1e-05
>sp|P29598|UROK_RAT Urokinase-type plasminogen activator precursor (uPA) (U-plasminogen
activator) [Contains: Urokinase-type plasminogen
activator long chain A; Urokinase-type plasminogen
activator short chain A; Urokinase-type plasminogen
activator chain B]
Length = 432
Score = 50.4 bits (119), Expect = 1e-06
Identities = 22/48 (45%), Positives = 31/48 (64%)
Frame = +2
Query: 77 NGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 220
+G+SGGPLIC+IDG ++G+VS A ++TRV Y L WI+
Sbjct: 374 SGDSGGPLICNIDGRPTLSGIVSWGSGCAEKNKPGVYTRVSYFLNWIQ 421
>sp|Q15661|TRYB1_HUMAN Tryptase beta-1 precursor (Tryptase 1) (Tryptase I)
Length = 275
Score = 48.9 bits (115), Expect = 4e-06
Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 14 DDDKLAR--YFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLF 187
DD ++ R C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++
Sbjct: 200 DDVRIVRDDMLCAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIY 257
Query: 188 TRVDYMLPWI 217
TRV Y L WI
Sbjct: 258 TRVTYYLDWI 267
>sp|P20231|TRYB2_HUMAN Tryptase beta-2 precursor (Tryptase 2) (Tryptase II)
Length = 275
Score = 48.9 bits (115), Expect = 4e-06
Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 14 DDDKLAR--YFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLF 187
DD ++ R C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++
Sbjct: 200 DDVRIVRDDMLCAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIY 257
Query: 188 TRVDYMLPWI 217
TRV Y L WI
Sbjct: 258 TRVTYYLDWI 267
>sp|P50343|MCPT6_RAT Mast cell protease 6 precursor (rMCP-6) (Tryptase)
Length = 274
Score = 48.9 bits (115), Expect = 4e-06
Identities = 25/59 (42%), Positives = 33/59 (55%)
Frame = +2
Query: 41 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 217
C+ N S G+SGGPL+C + G+ + AGVVS A A ++TRV Y L WI
Sbjct: 210 CAGNTRSDSC--QGDSGGPLVCKVKGTWLQAGVVSWGEGCAEANRPGIYTRVTYYLDWI 266
>sp|P00749|UROK_HUMAN Urokinase-type plasminogen activator precursor (uPA) (U-plasminogen
activator) [Contains: Urokinase-type plasminogen
activator long chain A; Urokinase-type plasminogen
activator short chain A; Urokinase-type plasminogen
activator chain B]
Length = 431
Score = 48.5 bits (114), Expect = 5e-06
Identities = 21/70 (30%), Positives = 36/70 (51%)
Frame = +2
Query: 11 FDDDKLARYFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFT 190
+ + + C+ + + G+SGGPL+CS+ G + G+VS A ++T
Sbjct: 351 YGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYT 410
Query: 191 RVDYMLPWIK 220
RV + LPWI+
Sbjct: 411 RVSHFLPWIR 420
>sp|P15157|TRYA_HUMAN Alpha-tryptase precursor (Tryptase 1)
Length = 275
Score = 48.5 bits (114), Expect = 5e-06
Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 14 DDDKLAR--YFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLF 187
DD ++ R C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++
Sbjct: 200 DDVRIIRDDMLCAGNTRRDSC--KGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIY 257
Query: 188 TRVDYMLPWI 217
TRV Y L WI
Sbjct: 258 TRVTYYLDWI 267
>sp|O18783|PLMN_MACEU Plasminogen precursor [Contains: Plasmin heavy chain A; Activation
peptide; Plasmin heavy chain A, short form; Plasmin
light chain B]
Length = 806
Score = 48.1 bits (113), Expect = 6e-06
Identities = 24/66 (36%), Positives = 34/66 (51%)
Frame = +2
Query: 41 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 220
C+ + +G G+SGGPLIC D V+ GV S + AR ++ RV + WI+
Sbjct: 741 CAGHLVGRGDSCQGDSGGPLICFEDDKYVLQGVTSWGLGCARPNKPGVYVRVSRYISWIE 800
Query: 221 LTMNNN 238
M NN
Sbjct: 801 DVMKNN 806
>sp|P06868|PLMN_BOVIN Plasminogen precursor [Contains: Plasmin heavy chain A; Activation
peptide; Plasmin heavy chain A, short form; Plasmin
light chain B]
Length = 812
Score = 47.8 bits (112), Expect = 8e-06
Identities = 22/66 (33%), Positives = 35/66 (53%)
Frame = +2
Query: 41 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 220
C+ + +G + G+SGGPL+C ++ GV S + AR ++ RV +PWI+
Sbjct: 747 CAGHLIGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSPYVPWIE 806
Query: 221 LTMNNN 238
TM N
Sbjct: 807 ETMRRN 812
>sp|P18291|NKP1_RAT Natural killer cell protease 1 precursor (RNKP-1) (Granzyme B)
Length = 248
Score = 47.4 bits (111), Expect = 1e-05
Identities = 28/70 (40%), Positives = 37/70 (52%)
Frame = +2
Query: 29 ARYFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYML 208
A C+ + A F G+SGGPL+C KV AG+VS N ++ R FT+V L
Sbjct: 185 ANEICAGDPKIKRASFRGDSGGPLVC----KKVAAGIVSYGQND--GSTPRAFTKVSTFL 238
Query: 209 PWIKLTMNNN 238
WIK TM +
Sbjct: 239 SWIKKTMKKS 248
>sp|P16227|UROK_PAPCY Urokinase-type plasminogen activator precursor (uPA) (U-plasminogen
activator) [Contains: Urokinase-type plasminogen
activator long chain A; Urokinase-type plasminogen
activator short chain A; Urokinase-type plasminogen
activator chain B]
Length = 433
Score = 47.0 bits (110), Expect = 1e-05
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +2
Query: 11 FDDDKLARYFCSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFT 190
+ + + C+ + + G+SGGPL+CSI G + G+VS A ++T
Sbjct: 353 YGSEVTTKMLCAADPQWETDSCQGDSGGPLVCSIQGHMTLTGIVSWGRGCALKDKPGVYT 412
Query: 191 RVDYMLPWI 217
RV LPWI
Sbjct: 413 RVSRFLPWI 421
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,507,659
Number of Sequences: 369166
Number of extensions: 668812
Number of successful extensions: 2057
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1906
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1959
length of database: 68,354,980
effective HSP length: 76
effective length of database: 54,315,120
effective search space used: 1683768720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)