Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_M13
(813 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8IUH5|ZDH17_HUMAN Palmitoyltransferase ZDHHC17 (Zinc fi... 160 3e-39
sp|Q80TN5|ZDH17_MOUSE Palmitoyltransferase ZDHHC17 (Zinc fi... 159 9e-39
sp|Q9CWU2|ZDH13_MOUSE Probable palmitoyltransferase ZDHHC13... 137 3e-32
sp|Q8IUH4|ZDH13_HUMAN Probable palmitoyltransferase ZDHHC13... 136 6e-32
sp|Q5NVB9|ZDH13_PONPY Probable palmitoyltransferase ZDHHC13... 136 8e-32
sp|Q4R690|ZDH13_MACFA Probable palmitoyltransferase ZDHHC13... 132 1e-30
sp|Q5KP49|AKR1_CRYNE Palmitoyltransferase AKR1 (Ankyrin rep... 110 5e-24
sp|Q755Y0|AKR1_ASHGO Palmitoyltransferase AKR1 (Ankyrin rep... 110 5e-24
sp|Q6C520|AKR1_YARLI Palmitoyltransferase AKR1 (Ankyrin rep... 102 1e-21
sp|Q876L5|AKR1_SACBA Palmitoyltransferase AKR1 (Ankyrin rep... 100 5e-21
>sp|Q8IUH5|ZDH17_HUMAN Palmitoyltransferase ZDHHC17 (Zinc finger DHHC domain-containing
protein 17) (DHHC-17) (Huntingtin-interacting protein
14) (Huntingtin-interacting protein 3)
(Huntingtin-interacting protein HYPH) (Putative
NF-kappa-B-activating protein 205) (Putative
MAPK-activating protein PM11)
Length = 632
Score = 160 bits (406), Expect = 3e-39
Identities = 89/220 (40%), Positives = 128/220 (58%), Gaps = 1/220 (0%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA +D +GGDL STPLHWA RQG L MV L+K GA+P++ DG+G +CIH+A+Q +T
Sbjct: 111 SKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHT 170
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDT-SGCTAGH 359
IVAYL+A G +VD+ D +GMT LMWAA R+ DP RLL+T+ +VN+ D TA H
Sbjct: 171 SIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALH 230
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN + L A + N +G + + ++ W+ N L E +G +
Sbjct: 231 WAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPS 290
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW 659
F+ +K FR M+ TP L +G + +++ W
Sbjct: 291 --FLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSW 328
>sp|Q80TN5|ZDH17_MOUSE Palmitoyltransferase ZDHHC17 (Zinc finger DHHC domain-containing
protein 17) (DHHC-17) (Huntingtin-interacting protein
14)
Length = 632
Score = 159 bits (402), Expect = 9e-39
Identities = 89/220 (40%), Positives = 127/220 (57%), Gaps = 1/220 (0%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA +D +GGDL STPLHWA RQG L MV L+K GA+P++ DG+G +CIH+A+Q +T
Sbjct: 111 SKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHT 170
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDT-SGCTAGH 359
IVAYL+A G +VD+ D +GMT LMWAA R+ DP RLL+T+ +VN+ D TA H
Sbjct: 171 SIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALH 230
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN + L A + N +G + + ++ W+ N L E +G +
Sbjct: 231 WAVLAGNTTVISLLLEAGGNVDAQNVKGESALDLAKQRKNVWMINHLQEARQAKGYDNPS 290
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW 659
F+ +K FR M+ TP L +G + ++ W
Sbjct: 291 --FLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLDIDSW 328
>sp|Q9CWU2|ZDH13_MOUSE Probable palmitoyltransferase ZDHHC13 (Zinc finger DHHC
domain-containing protein 13) (DHHC-13)
(Huntingtin-interacting protein 14 related protein)
(HIP14-related protein)
Length = 622
Score = 137 bits (345), Expect = 3e-32
Identities = 96/276 (34%), Positives = 151/276 (54%), Gaps = 6/276 (2%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA ID +GGDL STPLHWA+RQG L MV LLL++GA+P + DG+G + IH+A +
Sbjct: 103 SKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHM 162
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQD-TSGCTAGH 359
I+AYL++ G +V++ D++G T LM +A + GP+P L+ + ++++ D T T H
Sbjct: 163 PIIAYLISKGQSVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSVVDKTHQNTPLH 222
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN A+ +L A I N +G T + L+ Q I++ L E M+++K
Sbjct: 223 WAVAAGNVSAVDKLLEAGSSLDIRNAKGETPLDMALQSKNQLISHM---LRTEAKMRANK 279
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW-FKLIALVILF----LVIRF 704
F + +K F+ +IL+ +++ +G +L F+ + W K LV LF L RF
Sbjct: 280 QFRL-WRWLHKCELFLLLILS-MITLWAVGYILDFNSDSWLLKGCLLVALFFLTSLFPRF 337
Query: 705 GLGYLADERAQILCMFSLATCTTAYLCFTYLWFLMS 812
+GY +L T +L + W M+
Sbjct: 338 LVGYK-----------NLVYLPTVFLLSSIFWIFMT 362
>sp|Q8IUH4|ZDH13_HUMAN Probable palmitoyltransferase ZDHHC13 (Zinc finger DHHC
domain-containing protein 13) (DHHC-13)
(Huntingtin-interacting protein 14 related protein)
(HIP14-related protein) (Huntingtin-interacting protein
HIP3RP) (Putative NF-kappa-B-activating protein 209)
(Putative MAPK-activating protein PM03)
Length = 622
Score = 136 bits (343), Expect = 6e-32
Identities = 93/276 (33%), Positives = 146/276 (52%), Gaps = 6/276 (2%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA +D +GGDL STPLHWA+RQG L MV LLL++GA+P + DG+G + IH+A +
Sbjct: 103 SKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHM 162
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQD-TSGCTAGH 359
I+AYL++ G +V++ D++G T LM +A + GP+P L+ + ++N+ D T H
Sbjct: 163 PIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLH 222
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN A+ +L A I N +G T + L+ Q I + L E M++++
Sbjct: 223 WAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLI---IHMLKTEAKMRANQ 279
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW-FKLIALVILF----LVIRF 704
F L + +++ +++ IG +L F+ + W K LV LF L RF
Sbjct: 280 KF--RLWRWLQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRF 337
Query: 705 GLGYLADERAQILCMFSLATCTTAYLCFTYLWFLMS 812
+GY +L TA+L + W M+
Sbjct: 338 LVGYK-----------NLVYLPTAFLLSSVFWIFMT 362
>sp|Q5NVB9|ZDH13_PONPY Probable palmitoyltransferase ZDHHC13 (Zinc finger DHHC
domain-containing protein 13) (DHHC-13)
Length = 622
Score = 136 bits (342), Expect = 8e-32
Identities = 92/276 (33%), Positives = 146/276 (52%), Gaps = 6/276 (2%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA +D +GGDL STPLHWA+RQG L MV LLL++GA+P + DG+G + IH+A +
Sbjct: 103 SKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHM 162
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQD-TSGCTAGH 359
I+AYL++ G +V++ D++G T LM +A + GP+P L+ + ++N+ D T H
Sbjct: 163 PIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLH 222
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN A+ +L A I N +G T + L+ Q I + L E M++++
Sbjct: 223 WAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLI---IHMLKTEAKMRANQ 279
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW-FKLIALVILF----LVIRF 704
F L + +++ +++ +G +L F+ + W K LV LF L RF
Sbjct: 280 KF--RLWRWLQKCELFLLLMLSVITMWAVGYILDFNSDSWLLKGCLLVTLFFLTSLFPRF 337
Query: 705 GLGYLADERAQILCMFSLATCTTAYLCFTYLWFLMS 812
+GY +L TA+L + W M+
Sbjct: 338 LVGYK-----------NLVYLPTAFLLSSVFWIFMT 362
>sp|Q4R690|ZDH13_MACFA Probable palmitoyltransferase ZDHHC13 (Zinc finger DHHC
domain-containing protein 13) (DHHC-13)
Length = 622
Score = 132 bits (331), Expect = 1e-30
Identities = 91/276 (32%), Positives = 145/276 (52%), Gaps = 6/276 (2%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
SKGA +D +GGDL STPLHWA+RQG L MV LLL++GA+P + DG+G + IH+A +
Sbjct: 103 SKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLTDGEGFSSIHLAVLFQHM 162
Query: 183 HIVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQD-TSGCTAGH 359
I+AYL++ +V++ D++G T LM +A + GP+P L+ + ++N+ D T H
Sbjct: 163 PIIAYLISKRQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLH 222
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A GN A+ +L A I N +G T + L+ Q I + L E M++++
Sbjct: 223 WAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLI---IHMLKTEAKMRTNQ 279
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYW-FKLIALVILF----LVIRF 704
F L + +++ +++ +G +L F+ + W K LV LF L RF
Sbjct: 280 KF--RLWRWLQKCELFLLLMLSVITMWAVGYILDFNSDSWLLKGCLLVTLFFLTSLFPRF 337
Query: 705 GLGYLADERAQILCMFSLATCTTAYLCFTYLWFLMS 812
+GY +L TA+L + W M+
Sbjct: 338 LVGYK-----------NLIYLPTAFLLSSIFWIFMT 362
>sp|Q5KP49|AKR1_CRYNE Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1)
Length = 776
Score = 110 bits (275), Expect = 5e-24
Identities = 61/131 (46%), Positives = 80/131 (61%)
Frame = +3
Query: 9 GANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYTHI 188
GA+ID IGG+LK+TPL WA R G L +V LL+ GA+PNI D QG +H+ + S
Sbjct: 127 GADIDAIGGELKATPLQWAARNGHLYVVHLLISRGADPNIHDSQGFNTLHLITHSSAVMP 186
Query: 189 VAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDTSGCTAGHYAA 368
+ Y+L V +D KD G TALMWAA + + LLI GA+VN D +G T H+AA
Sbjct: 187 LLYMLHQPVAIDEKDTDGHTALMWAAYQGDALS-VDLLIRHGASVNSTDNAGMTPLHWAA 245
Query: 369 QLGNFVALKQL 401
GN V++ L
Sbjct: 246 VKGNKVSIMHL 256
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/67 (34%), Positives = 37/67 (55%)
Frame = +3
Query: 48 TPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYTHIVAYLLAYGVNVDL 227
T L WA QG V LL+++GA+ N D G+T +H A+ + +L+ G ++D
Sbjct: 206 TALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVEAGASLDA 265
Query: 228 KDISGMT 248
K+ +G T
Sbjct: 266 KEEAGKT 272
>sp|Q755Y0|AKR1_ASHGO Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1)
Length = 724
Score = 110 bits (275), Expect = 5e-24
Identities = 79/238 (33%), Positives = 121/238 (50%), Gaps = 1/238 (0%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
++GA++++ GGDL++TPLHWA + G + +V LL++GA+P I D QG +H ++ S
Sbjct: 112 AQGADVNIKGGDLEATPLHWASKSGYVYIVHCLLEHGADPLITDRQGYNLLHTSTFSSEV 171
Query: 183 HIVAYLLAYG-VNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDTSGCTAGH 359
++ Y+L G + VD D +G TAL WAA + P+ + L+ + A+V + DT G T H
Sbjct: 172 MLITYVLFTGQIPVDSPDPTGKTALHWAAYQG-DPNTVEALLKFDADVRVVDTGGFTPLH 230
Query: 360 YAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGMKSHK 539
+A G+ LK L D + NN+G I + N Q L + E G +
Sbjct: 231 WATVKGHPHVLKALIEHGSDVFLKNNDGKNALMIAQEMNTQ---KALQNALYECGF-NKD 286
Query: 540 NFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYWFKLIALVILFLVIRFGLG 713
F I KN + TP +L +GL+L F + L L L V+ G G
Sbjct: 287 GFAIRKYFKNPMHAKMVTFFTP---WLILGLILSFFAYFSILLAILGCLLTVLAAGYG 341
>sp|Q6C520|AKR1_YARLI Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1)
Length = 702
Score = 102 bits (254), Expect = 1e-21
Identities = 58/157 (36%), Positives = 89/157 (56%)
Frame = +3
Query: 6 KGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYTH 185
+GA +D GG L TPLHWA R+GL+ +V L++NGA+P D QG +H+A+ S
Sbjct: 106 QGAVVDAKGGQLNGTPLHWACRRGLVYIVHYLIQNGADPLRSDVQGYNALHLATHSSNVM 165
Query: 186 IVAYLLAYGVNVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDTSGCTAGHYA 365
++ YLL G+ VD +D +G TAL WAA + + +L+ WG++V I DT G H+
Sbjct: 166 LLVYLLHQGLPVDCQDPNGRTALHWAAYQGDALS-VDVLLRWGSDVKITDTQGFLPLHWG 224
Query: 366 AQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKN 476
G+ +L +L D +++G T H + + N
Sbjct: 225 IVNGSRNSLARLIEEGSDMYAKSSDGKTPHVMAAEMN 261
>sp|Q876L5|AKR1_SACBA Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1)
Length = 763
Score = 100 bits (249), Expect = 5e-21
Identities = 77/244 (31%), Positives = 119/244 (48%), Gaps = 5/244 (2%)
Frame = +3
Query: 3 SKGANIDVIGGDLKSTPLHWAVRQGLLEMVALLLKNGANPNIFDGQGLTCIHVASQLSYT 182
S+GA+++ G L +TPLHWA R G + +V LLK+GA+P + D QG +H++ S
Sbjct: 129 SQGADVNSRAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNI 188
Query: 183 HIVAYLLAYGV-----NVDLKDISGMTALMWAAARSTGPDPIRLLITWGANVNIQDTSGC 347
+V Y+L V +VD +D G T+L+WAA + + +L+ +GAN+ I DT G
Sbjct: 189 MLVLYVLFSVVSKGLLDVDCQDPKGRTSLLWAAYQGDSL-TVAVLLKFGANIKIADTEGF 247
Query: 348 TAGHYAAQLGNFVALKQLNIASIDWRIINNEGITVHQILLKKNMQWIANKLDELMIERGM 527
T H+ G LK L D+ + G I + N + L E +I G
Sbjct: 248 TPLHWGTVKGQPHVLKYLIQDGADFFQKTDAGKDCFAIAQEMNTVY---SLREALIHSGF 304
Query: 528 KSHKNFFINLTAKNKNFRFITMILTPILSFLFIGLLLHFSMNYWFKLIALVILFLVIRFG 707
+ K+++ + +T LTP + FL + L +N F +I L +L L G
Sbjct: 305 NNDGYPIKKWFKKSQHAKLVT-FLTPFV-FLGLAFALFSHVNPLFAIIVLFLLTLATNKG 362
Query: 708 LGYL 719
L L
Sbjct: 363 LNKL 366
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,700,198
Number of Sequences: 369166
Number of extensions: 1819659
Number of successful extensions: 6723
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5312
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6196
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)