Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_L21
(476 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P62194|PRS8_BOVIN 26S protease regulatory subunit 8 (Pro... 227 1e-59
sp|P46470|PRS8_XENLA 26S protease regulatory subunit 8 (SUG... 227 1e-59
sp|O18413|PRS8_DROME 26S protease regulatory subunit 8 225 5e-59
sp|P54814|PRS8_MANSE 26S protease regulatory subunit 8 (18-... 225 5e-59
sp|Q25544|PRS8_NAEFO 26S protease regulatory subunit 8 homo... 200 2e-51
sp|P34124|PRS8_DICDI 26S protease regulatory subunit 8 (TAT... 200 2e-51
sp|P41836|PRS8_SCHPO 26S protease regulatory subunit 8 homo... 197 1e-50
sp|Q01939|PRS8_YEAST 26S protease regulatory subunit 8 homo... 196 3e-50
sp|Q8U4H3|PSMR_PYRFU Proteasome-activating nucleotidase (Pr... 149 2e-36
sp|Q5JHS5|PSMR_PYRKO Proteasome-activating nucleotidase (Pr... 147 1e-35
>sp|P62194|PRS8_BOVIN 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5)
sp|P62196|PRS8_MOUSE 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (mSUG1)
sp|P62195|PRS8_HUMAN 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (Thyroid
hormone receptor interacting protein 1) (TRIP1)
sp|P62198|PRS8_RAT 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (Thyroid
hormone receptor interacting protein 1) (TRIP1)
sp|P62197|PRS8_PIG 26S protease regulatory subunit 8 (Proteasome subunit p45)
(p45/SUG) (Proteasome 26S subunit ATPase 5) (TAT-binding
protein homolog 10) (TBP10)
Length = 406
Score = 227 bits (578), Expect = 1e-59
Identities = 116/135 (85%), Positives = 125/135 (92%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE T+NIK+IMATNRIDILDSALLRPGRIDRKIEFP PNE
Sbjct: 264 GGDSEVQRTMLELL-NQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
EARLDILKIHSRKMNLTRGI+LRK AELMPGASGAE+KGVCTEAGMYALRERRVHVTQED
Sbjct: 323 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 382
Query: 363 FELAVAKIMQKDSEE 407
FE+AVAK+MQKDSE+
Sbjct: 383 FEMAVAKVMQKDSEK 397
>sp|P46470|PRS8_XENLA 26S protease regulatory subunit 8 (SUG1 homolog) (xSUG1)
Length = 461
Score = 227 bits (578), Expect = 1e-59
Identities = 116/135 (85%), Positives = 125/135 (92%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE T+NIK+IMATNRIDILDSALLRPGRIDRKIEFP PNE
Sbjct: 258 GGDSEVQRTMLELL-NQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 316
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
EARLDILKIHSRKMNLTRGI+LRK AELMPGASGAE+KGVCTEAGMYALRERRVHVTQED
Sbjct: 317 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 376
Query: 363 FELAVAKIMQKDSEE 407
FE+AVAK+MQKDSE+
Sbjct: 377 FEMAVAKVMQKDSEK 391
>sp|O18413|PRS8_DROME 26S protease regulatory subunit 8
Length = 405
Score = 225 bits (573), Expect = 5e-59
Identities = 115/135 (85%), Positives = 124/135 (91%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE T+NIK+IMATNRIDILD ALLRPGRIDRKIEFP PNE
Sbjct: 263 GGDSEVQRTMLELL-NQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNE 321
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
EARLDILKIHSRKMNLTRGI+LRK AELMPGASGAE+KGVCTEAGMYALRERRVHVTQED
Sbjct: 322 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 381
Query: 363 FELAVAKIMQKDSEE 407
FE+AVAK+MQKDSE+
Sbjct: 382 FEMAVAKVMQKDSEK 396
>sp|P54814|PRS8_MANSE 26S protease regulatory subunit 8 (18-56 protein)
Length = 402
Score = 225 bits (573), Expect = 5e-59
Identities = 115/135 (85%), Positives = 124/135 (91%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE T+NIK+IMATNRIDILD ALLRPGRIDRKIEFP PNE
Sbjct: 260 GGDSEVQRTMLELL-NQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNE 318
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
EARLDILKIHSRKMNLTRGI+LRK AELMPGASGAE+KGVCTEAGMYALRERRVHVTQED
Sbjct: 319 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 378
Query: 363 FELAVAKIMQKDSEE 407
FE+AVAK+MQKDSE+
Sbjct: 379 FEMAVAKVMQKDSEK 393
>sp|Q25544|PRS8_NAEFO 26S protease regulatory subunit 8 homolog (TAT-binding protein
homolog)
Length = 414
Score = 200 bits (508), Expect = 2e-51
Identities = 103/134 (76%), Positives = 115/134 (85%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE TQNIKIIMATNRIDILD ALLRPGRIDRKIEFP PNE
Sbjct: 272 GGDSEVQRTMLELL-NQLDGFESTQNIKIIMATNRIDILDPALLRPGRIDRKIEFPNPNE 330
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
ARLDILKIHSR+MNLTRGI+LRK A ++ GASGAE+K CTEAGM+ALRERRVHVTQED
Sbjct: 331 LARLDILKIHSRRMNLTRGINLRKIASMLGGASGAEIKATCTEAGMFALRERRVHVTQED 390
Query: 363 FELAVAKIMQKDSE 404
E+AVAK+M++ E
Sbjct: 391 LEMAVAKVMKRGDE 404
>sp|P34124|PRS8_DICDI 26S protease regulatory subunit 8 (TAT-binding protein homolog 10)
Length = 389
Score = 200 bits (508), Expect = 2e-51
Identities = 100/135 (74%), Positives = 117/135 (86%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE T+NIK++M TNRIDILD ALLRPGRIDRKIEFP P +
Sbjct: 247 GGDSEVQRTMLELL-NQLDGFESTKNIKVLMCTNRIDILDPALLRPGRIDRKIEFPNPGD 305
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
RLDILKIHSRKMNLTRGI+L+K ++ M GASGAE+K VCTEAGMYALRERRVHV+QED
Sbjct: 306 AGRLDILKIHSRKMNLTRGINLKKISDKMNGASGAELKAVCTEAGMYALRERRVHVSQED 365
Query: 363 FELAVAKIMQKDSEE 407
FE+AV+K+M+KDSE+
Sbjct: 366 FEMAVSKVMKKDSEQ 380
>sp|P41836|PRS8_SCHPO 26S protease regulatory subunit 8 homolog (Protein let1)
Length = 403
Score = 197 bits (501), Expect = 1e-50
Identities = 104/140 (74%), Positives = 117/140 (83%), Gaps = 1/140 (0%)
Frame = +3
Query: 6 GDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNEE 185
GDSEVQR + + LDGFE T+NIK+IMATNRIDILD ALLRPGRIDRKIEFP P+ E
Sbjct: 262 GDSEVQRTMLELL-NQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPSAE 320
Query: 186 ARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQEDF 365
AR +IL+IHSR MNLTRGIDL+ AE M GASGAE+KGVCTEAGM+ALRERRVHVTQEDF
Sbjct: 321 ARAEILRIHSRSMNLTRGIDLKSIAEKMNGASGAELKGVCTEAGMFALRERRVHVTQEDF 380
Query: 366 ELAVAKIMQK-DSEEKRVDK 422
ELAVAK++ K DS E + K
Sbjct: 381 ELAVAKVLNKGDSGEMSLQK 400
>sp|Q01939|PRS8_YEAST 26S protease regulatory subunit 8 homolog (SUG1 protein) (CIM3
protein) (TAT-binding protein TBY1)
Length = 405
Score = 196 bits (497), Expect = 3e-50
Identities = 100/134 (74%), Positives = 114/134 (85%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GGDSEVQR + + LDGFE ++NIKIIMATNR+DILD ALLRPGRIDRKIEFP P+
Sbjct: 263 GGDSEVQRTMLELL-NQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSV 321
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
AR +IL+IHSRKMNLTRGI+LRK AE M G SGA++KGVCTEAGMYALRERR+HVTQED
Sbjct: 322 AARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQED 381
Query: 363 FELAVAKIMQKDSE 404
FELAV K+M K+ E
Sbjct: 382 FELAVGKVMNKNQE 395
>sp|Q8U4H3|PSMR_PYRFU Proteasome-activating nucleotidase (Proteasome regulatory subunit)
Length = 396
Score = 149 bits (377), Expect = 2e-36
Identities = 78/143 (54%), Positives = 104/143 (72%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GG+ EV R + + +DGF+P N+K+I ATNR DILD ALLRPGR DR IE P P+
Sbjct: 252 GGEREVNRTLMQLL-AEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDF 310
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
E RL+ILK+H+R+M L RG+DLR AEL GASGA++K + TEAGM+A+RERR +VTQED
Sbjct: 311 EGRLEILKVHTRRMKL-RGVDLRLIAELTEGASGADLKAIATEAGMFAIRERRTYVTQED 369
Query: 363 FELAVAKIMQKDSEEKRVDKEAM 431
F A+ K++ EK++ ++ M
Sbjct: 370 FLKAIDKVL---GNEKKIIQQIM 389
>sp|Q5JHS5|PSMR_PYRKO Proteasome-activating nucleotidase (Proteasome regulatory subunit)
Length = 397
Score = 147 bits (371), Expect = 1e-35
Identities = 76/141 (53%), Positives = 104/141 (73%)
Frame = +3
Query: 3 GGDSEVQRNNVGIY*INLDGFEPTQNIKIIMATNRIDILDSALLRPGRIDRKIEFPAPNE 182
GG+ EV R + + +DGF+P N+K+I ATNR DILD ALLRPGR DR IE P P+
Sbjct: 253 GGEREVNRTLMQLL-AEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDY 311
Query: 183 EARLDILKIHSRKMNLTRGIDLRKFAELMPGASGAEMKGVCTEAGMYALRERRVHVTQED 362
+ RL+ILK+H+RKMNL +G+DLR AE+ GASGA++K + TEAGM+A+R+RR +VTQ+D
Sbjct: 312 QGRLEILKVHTRKMNL-KGVDLRVIAEITEGASGADLKAIATEAGMFAIRDRRTYVTQDD 370
Query: 363 FELAVAKIMQKDSEEKRVDKE 425
F AV K++ EKR+ ++
Sbjct: 371 FLKAVDKVI---GSEKRLAQQ 388
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,891,948
Number of Sequences: 369166
Number of extensions: 1001066
Number of successful extensions: 3148
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3109
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2832714465
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)