Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_K18
(911 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P33435|MMP13_MOUSE Collagenase 3 precursor (Matrix metal... 52 2e-06
sp|O62806|MMP13_RABIT Collagenase 3 precursor (Matrix metal... 50 7e-06
sp|P45452|MMP13_HUMAN Collagenase 3 precursor (Matrix metal... 49 1e-05
sp|O18927|MMP13_HORSE Collagenase 3 precursor (Matrix metal... 49 1e-05
sp|P23097|MMP13_RAT Collagenase 3 precursor (Matrix metallo... 49 3e-05
sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 precursor... 49 3e-05
sp|P51512|MMP16_HUMAN Matrix metalloproteinase-16 precursor... 48 3e-05
sp|Q9XT90|MMP14_PIG Matrix metalloproteinase-14 precursor (... 48 3e-05
sp|Q9R0S2|MMP24_MOUSE Matrix metalloproteinase-24 precursor... 48 3e-05
sp|Q99PW6|MMP24_RAT Matrix metalloproteinase-24 precursor (... 48 3e-05
>sp|P33435|MMP13_MOUSE Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 472
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 4/180 (2%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRSNKKREQSANEK 180
L HS DP ALM P Y Y ++ F LPDDD QG F+YG + + K E+
Sbjct: 231 LDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQGIQFLYGPGDEDPNPKHPKTPEKCDPAL 289
Query: 181 ELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQLPNQLFDSDALF 360
L IT++ D + +V + SF +LPN + DA
Sbjct: 290 SLDAITSLRGETMIFKDRFFWRLHPQQVEAELFLTKSF-------WPELPNHV---DAA- 338
Query: 361 YDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTAAIVRDKTGKS 528
Y++ R +F F+G + ++ NG + IS+L + R++AA+ + TGK+
Sbjct: 339 YEHPSRDLMFIFRGRKFWALNGYDILEGYPRKISDLGFPKE---VKRLSAAVHFENTGKT 395
>sp|O62806|MMP13_RABIT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 471
Score = 50.4 bits (119), Expect = 7e-06
Identities = 50/180 (27%), Positives = 80/180 (44%), Gaps = 4/180 (2%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRSNKKREQSANEK 180
L HS DP ALM P Y Y ++ F LPDDD QG +YG + + K ++
Sbjct: 230 LDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSL 288
Query: 181 ELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQLPNQLFDSDALF 360
L IT++ D + +V + SF +LPN++ DA
Sbjct: 289 SLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSF-------WPELPNRI---DAA- 337
Query: 361 YDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTAAIVRDKTGKS 528
Y++ R +F F+G + ++ NG + +SEL R +++AA+ + TGK+
Sbjct: 338 YEHPARDLIFIFRGKKFWAPNGYDILEGYPQKLSELGFpre---VKKISAAVHFEDTGKT 394
>sp|P45452|MMP13_HUMAN Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 471
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/179 (26%), Positives = 77/179 (43%), Gaps = 3/179 (1%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRSNKKREQSANEK 180
L HS DP ALM P Y Y ++ F LPDDD QG +YG + + K ++
Sbjct: 230 LDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSL 288
Query: 181 ELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQLPNQLFDSDALF 360
L IT++ D + +V + SF +LPN++ DA +
Sbjct: 289 SLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSF-------WPELPNRI---DAAY 338
Query: 361 YDYSGRRFVFFKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTAAIVRDKTGKS 528
S F+G + ++ NG + ISEL + + +++AA+ + TGK+
Sbjct: 339 EHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKE---VKKISAAVHFEDTGKT 394
>sp|O18927|MMP13_HORSE Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
Length = 472
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 4/180 (2%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRSNKKREQSANEK 180
L HS DP ALM P Y Y ++ F LPDDD QG ++YG + + K ++
Sbjct: 231 LDHSKDPGALMFPIYT-YTGKSHFVLPDDDVQGIQYLYGPGDEDPNPKHPKTPDKCDPSL 289
Query: 181 ELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQLPNQLFDSDALF 360
L IT++ D + V + SF +LPN++ DA
Sbjct: 290 SLDAITSLRGETMVFKDRFFWRLHPQLVDAELFLTKSF-------WPELPNRI---DAA- 338
Query: 361 YDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTAAIVRDKTGKS 528
Y++ + +F F+G + ++ NG + ISEL + +++AA+ + TGK+
Sbjct: 339 YEHPSKDLIFIFRGRKFWALNGYDILEGYPQKISELGFPKD---VKKISAAVHFEDTGKT 395
>sp|P23097|MMP13_RAT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
(UMRCASE)
Length = 466
Score = 48.5 bits (114), Expect = 3e-05
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 4/180 (2%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNGKVFVRSNKKREQSANEK 180
L HS DP ALM P Y Y ++ F LPDDD QG +YG + + K E+
Sbjct: 225 LDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPEKCDPAL 283
Query: 181 ELCNITNINSAFQYSDDNIYVVTDKNKVFRIIHSNNSFRVDASFKTLQLPNQLFDSDALF 360
L IT++ D + +V + SF +LPN + DA
Sbjct: 284 SLDAITSLRGETMIFKDRFFWRLHPQQVEPELFLTKSF-------WPELPNHV---DAA- 332
Query: 361 YDYSGRRFVF-FKGNRVFSANGVKLEN---LTISELNVTRPGGFQGRVTAAIVRDKTGKS 528
Y++ R +F F+G + ++ NG + IS+L + R++AA+ + TGK+
Sbjct: 333 YEHPSRDLMFIFRGRKFWALNGYDIMEGYPRKISDLGFPKE---VKRLSAAVHFEDTGKT 389
>sp|P53690|MMP14_MOUSE Matrix metalloproteinase-14 precursor (MMP-14) (Membrane-type
matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1)
(Membrane-type-1 matrix metalloproteinase) (MT1-MMP)
(MT1MMP) (MMP-X1) (MT-MMP)
Length = 582
Score = 48.5 bits (114), Expect = 3e-05
Identities = 23/43 (53%), Positives = 32/43 (74%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNG 129
L HSNDP+A+M+P+Y +EN F LPDDD +G +YG+K+G
Sbjct: 247 LEHSNDPSAIMSPFYQWMDTEN-FVLPDDDRRGIQQLYGSKSG 288
>sp|P51512|MMP16_HUMAN Matrix metalloproteinase-16 precursor (MMP-16) (Membrane-type
matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3)
(Membrane-type-3 matrix metalloproteinase) (MT3-MMP)
(MT3MMP) (MMP-X2)
Length = 607
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/39 (58%), Positives = 29/39 (74%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 117
L HSNDP A+MAP+Y Y+ ++FKLP+DD QG IYG
Sbjct: 254 LEHSNDPTAIMAPFYQ-YMETDNFKLPNDDLQGIQKIYG 291
>sp|Q9XT90|MMP14_PIG Matrix metalloproteinase-14 precursor (MMP-14) (Membrane-type
matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1)
(Membrane-type-1 matrix metalloproteinase) (MT1-MMP)
(MT1MMP)
Length = 580
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/43 (53%), Positives = 32/43 (74%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYGTKNG 129
L HSNDP+A+MAP+Y +EN F LPDDD +G +YG+++G
Sbjct: 245 LEHSNDPSAIMAPFYQWMDTEN-FVLPDDDRRGIQQLYGSESG 286
>sp|Q9R0S2|MMP24_MOUSE Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type
matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5
matrix metalloproteinase) (MT5-MMP) (MMP-21)
Length = 618
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/39 (58%), Positives = 29/39 (74%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 117
L HSNDP+A+MAP+Y Y+ ++FKLP DD QG IYG
Sbjct: 263 LEHSNDPSAIMAPFYQ-YMETHNFKLPQDDLQGIQKIYG 300
>sp|Q99PW6|MMP24_RAT Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type
matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5
matrix metalloproteinase) (MT5-MMP)
Length = 618
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/39 (58%), Positives = 29/39 (74%)
Frame = +1
Query: 1 LFHSNDPNALMAPWYGGYISENDFKLPDDDSQGAAFIYG 117
L HSNDP+A+MAP+Y Y+ ++FKLP DD QG IYG
Sbjct: 263 LEHSNDPSAIMAPFYQ-YMETHNFKLPQDDLQGIQKIYG 300
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,872,886
Number of Sequences: 369166
Number of extensions: 1919710
Number of successful extensions: 5266
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5020
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5225
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9270587090
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)