Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_001_J13 (597 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP ... 235 7e-62 sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86) 234 1e-61 sp|O61998|HSP90_BRUPA Heat shock protein 90 234 2e-61 sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86) 233 2e-61 sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86) 233 4e-61 sp|Q9GKX7|HS90A_HORSE Heat shock protein HSP 90-alpha (HSP 86) 233 4e-61 sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha 232 6e-61 sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 8... 231 1e-60 sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84) 231 1e-60 sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 8... 231 1e-60
>sp|P07901|HS90A_MOUSE Heat shock protein HSP 90-alpha (HSP 86) (Tumor specific transplantation 86 kDa antigen) (TSTA) Length = 733 Score = 235 bits (599), Expect = 7e-62 Identities = 117/161 (72%), Positives = 139/161 (86%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 631 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691 Query: 413 MIKLGLGIEVDDVEMDATEAG---DVPVVASTAEEDAGKME 526 MIKLGLGI+ DD +D T A ++P + ++D +ME Sbjct: 692 MIKLGLGIDEDDPTVDDTSAAVTEEMPPL--EGDDDTSRME 730
>sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha (HSP 86) Length = 732 Score = 234 bits (597), Expect = 1e-61 Identities = 117/161 (72%), Positives = 138/161 (85%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA Sbjct: 571 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 630 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 631 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 690 Query: 413 MIKLGLGIEVDDVEMDATEAG---DVPVVASTAEEDAGKME 526 MIKLGLGI+ DD D T A ++P + ++D +ME Sbjct: 691 MIKLGLGIDEDDPTADDTSAAVTEEMPPL--EGDDDTSRME 729
>sp|O61998|HSP90_BRUPA Heat shock protein 90 Length = 717 Score = 234 bits (596), Expect = 2e-61 Identities = 122/163 (74%), Positives = 143/163 (87%), Gaps = 5/163 (3%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCKVMKDIL+KKVEKV VSNRLVSSPCCIVTS+YGWSANMERIMKAQALRDSSTMGYMAA Sbjct: 553 LCKVMKDILEKKVEKVAVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAA 612 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHS++K L+ RV+ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ+H +RI+R Sbjct: 613 KKHLEINPDHSVIKALRERVEADKNDKTVKDLVVLLFETALLSSGFSLEDPQLHASRIYR 672 Query: 413 MIKLGLGI-EVDDVEMDATEAGD----VPVVASTAEEDAGKME 526 MIKLGL I E ++ E A+ +G+ VP + AEEDA +ME Sbjct: 673 MIKLGLDITEDEEEEAIASVSGEKDECVPNLVG-AEEDASRME 714
>sp|P46633|HS90A_CRIGR Heat shock protein HSP 90-alpha (HSP 86) Length = 733 Score = 233 bits (595), Expect = 2e-61 Identities = 116/161 (72%), Positives = 139/161 (86%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERI+KAQALRD+STMGYMAA Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIIKAQALRDNSTMGYMAA 631 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691 Query: 413 MIKLGLGIEVDDVEMDATEAG---DVPVVASTAEEDAGKME 526 MIKLGLGI+ DD +D T A ++P + ++D +ME Sbjct: 692 MIKLGLGIDEDDPTVDDTSAAVTEEMPPL--EGDDDTSRME 730
>sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha (HSP 86) Length = 733 Score = 233 bits (593), Expect = 4e-61 Identities = 116/161 (72%), Positives = 138/161 (85%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA Sbjct: 572 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 631 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 632 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 691 Query: 413 MIKLGLGIEVDDVEMDATEAG---DVPVVASTAEEDAGKME 526 MIKLGLGI+ DD D + A ++P + ++D +ME Sbjct: 692 MIKLGLGIDEDDPTADDSSAAVTEEMPPL--EGDDDTSRME 730
>sp|Q9GKX7|HS90A_HORSE Heat shock protein HSP 90-alpha (HSP 86) Length = 719 Score = 233 bits (593), Expect = 4e-61 Identities = 116/161 (72%), Positives = 138/161 (85%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA Sbjct: 561 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 620 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 621 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 680 Query: 413 MIKLGLGIEVDDVEMDATEAG---DVPVVASTAEEDAGKME 526 MIKLGLGI+ DD D + A ++P + ++D +ME Sbjct: 681 MIKLGLGIDEDDPTADDSSAAVTEEMPPL--EGDDDTSRME 719
>sp|P11501|HS90A_CHICK Heat shock protein HSP 90-alpha Length = 728 Score = 232 bits (591), Expect = 6e-61 Identities = 115/159 (72%), Positives = 136/159 (85%), Gaps = 1/159 (0%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS YGW+ANMERIMKAQALRD+STMGYMAA Sbjct: 567 LCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 626 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDHSI++TL+ + +ADKNDKSVKDLV+LLYET+LLSSGF+LEDPQ H NRI+R Sbjct: 627 KKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYR 686 Query: 413 MIKLGLGIEVDDVEM-DATEAGDVPVVASTAEEDAGKME 526 MIKLGLGI+ DD +A+ A + ++D +ME Sbjct: 687 MIKLGLGIDEDDTAAEEASPAVTEEMPPLEGDDDTSRME 725
>sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta (HSP 84) (HSP 90) Length = 724 Score = 231 bits (589), Expect = 1e-60 Identities = 115/161 (71%), Positives = 139/161 (86%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682 Query: 413 MIKLGLGIEVDDV---EMDATEAGDVPVVASTAEEDAGKME 526 MIKLGLGI+ D+V E +A ++P + +EDA +ME Sbjct: 683 MIKLGLGIDEDEVAAEEPNAAVPDEIPPL--EGDEDASRME 721
>sp|Q9GKX8|HS90B_HORSE Heat shock protein HSP 90-beta (HSP 84) Length = 724 Score = 231 bits (588), Expect = 1e-60 Identities = 115/161 (71%), Positives = 138/161 (85%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682 Query: 413 MIKLGLGIEVDDV---EMDATEAGDVPVVASTAEEDAGKME 526 MIKLGLGI+ D+V E A ++P + +EDA +ME Sbjct: 683 MIKLGLGIDEDEVAAEEPSAAVPDEIPPL--EGDEDASRME 721
>sp|P11499|HS90B_MOUSE Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA) Length = 724 Score = 231 bits (588), Expect = 1e-60 Identities = 115/161 (71%), Positives = 138/161 (85%), Gaps = 3/161 (1%) Frame = +2 Query: 53 LCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAA 232 LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS YGW+ANMERIMKAQALRD+STMGYM A Sbjct: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622 Query: 233 KKHLEINPDHSIMKTLKARVDADKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHR 412 KKHLEINPDH I++TL+ + +ADKNDK+VKDLV+LL+ET+LLSSGF+LEDPQ H NRI+R Sbjct: 623 KKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR 682 Query: 413 MIKLGLGIEVDDV---EMDATEAGDVPVVASTAEEDAGKME 526 MIKLGLGI+ D+V E A ++P + +EDA +ME Sbjct: 683 MIKLGLGIDEDEVTAEEPSAAVPDEIPPL--EGDEDASRME 721
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,078,567 Number of Sequences: 369166 Number of extensions: 959342 Number of successful extensions: 2714 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2619 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2664 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4553075865 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)