Planarian EST Database


Dr_sW_001_J12

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_001_J12
         (733 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P30101|PDIA3_HUMAN  Protein disulfide-isomerase A3 precur...   227   3e-59
sp|P38657|PDIA3_BOVIN  Protein disulfide-isomerase A3 precur...   227   3e-59
sp|P27773|PDIA3_MOUSE  Protein disulfide-isomerase A3 precur...   222   9e-58
sp|P11598|PDIA3_RAT  Protein disulfide-isomerase A3 precurso...   220   3e-57
sp|P38658|ERP60_SCHMA  Probable protein disulfide-isomerase ...   207   2e-53
sp|P13667|PDIA4_HUMAN  Protein disulfide-isomerase A4 precur...   174   3e-43
sp|P38659|PDIA4_RAT  Protein disulfide-isomerase A4 precurso...   171   2e-42
sp|P08003|PDIA4_MOUSE  Protein disulfide-isomerase A4 precur...   170   4e-42
sp|P55059|PDI_HUMIN  Protein disulfide-isomerase precursor (...   162   1e-39
sp|P34329|PDIA4_CAEEL  Probable protein disulfide-isomerase ...   156   6e-38
>sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
           ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
           (58 kDa glucose regulated protein)
          Length = 505

 Score =  227 bits (578), Expect = 3e-59
 Identities = 109/188 (57%), Positives = 139/188 (73%), Gaps = 2/188 (1%)
 Frame = +1

Query: 1   FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMAEVFTME--AFEKFINDFLN 174
           FA+++ +  SHELS+FG+ES       +  R  K +KF M E F+ +  A E+F+ D+ +
Sbjct: 299 FAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFD 358

Query: 175 EQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEE 354
             +  YLKSE IPE ND PVKVVVA+NFD +VN+  KDVLIEFYAPWCGHCK+L PKY+E
Sbjct: 359 GNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKE 418

Query: 355 LAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLK 534
           L +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE+ D + 
Sbjct: 419 LGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFIS 478

Query: 535 YIASESTS 558
           Y+  E+T+
Sbjct: 479 YLQREATN 486

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
 Frame = +1

Query: 253 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 423
           NF++ ++D      +L+EF+APWCGHCK LAP+YE  A +L G   + +AK+D TAN + 
Sbjct: 34  NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91

Query: 424 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
            + Y V+G+PT+       +    +Y+G R  D ++ ++  ++
Sbjct: 92  CNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQA 132
>sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
           ER-60) (ERP60) (58 kDa microsomal protein) (P58) (ERp57)
          Length = 505

 Score =  227 bits (578), Expect = 3e-59
 Identities = 108/188 (57%), Positives = 138/188 (73%), Gaps = 2/188 (1%)
 Frame = +1

Query: 1   FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMAEVFTME--AFEKFINDFLN 174
           FA+++ +  SHELS+FG+ES       +  R  K +KF M E F+ +  A E+F+ D+ +
Sbjct: 299 FAVASRKTFSHELSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFD 358

Query: 175 EQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEE 354
             +  YLKSE IPE ND PVKVVVA+NFD +VN+  KDVLIEFYAPWCGHCK+L PKY+E
Sbjct: 359 GNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKE 418

Query: 355 LAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLK 534
           L +KL  + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE+ D + 
Sbjct: 419 LGEKLRKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFIS 478

Query: 535 YIASESTS 558
           Y+  E+T+
Sbjct: 479 YLKREATN 486

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
 Frame = +1

Query: 253 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 423
           NF++ + D      +L+EF+APWCGHCK LAP+YE  A +L G   + +AK+D TAN + 
Sbjct: 34  NFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91

Query: 424 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
            + Y V+G+PT+       ++   +Y+G R  D ++ ++  ++
Sbjct: 92  CNKYGVSGYPTLKIFRDGEESG--AYDGPRTADGIVSHLKKQA 132
>sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 precursor (Disulfide isomerase
           ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
          Length = 504

 Score =  222 bits (565), Expect = 9e-58
 Identities = 106/188 (56%), Positives = 139/188 (73%), Gaps = 2/188 (1%)
 Frame = +1

Query: 1   FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMAEVFTME--AFEKFINDFLN 174
           FA+++ +  SHELS+F +ES       +  R  K +KF M E F+ +  A E+F+ ++ +
Sbjct: 298 FAVASRKTFSHELSDFSLESTTGEVPVVAIRTAKGEKFVMQEEFSRDGKALEQFLQEYFD 357

Query: 175 EQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEE 354
             +  YLKSE IPE N+ PVKVVVA+NFD +VN+  KDVLIEFYAPWCGHCK+L PKY+E
Sbjct: 358 GNLKRYLKSEPIPESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKE 417

Query: 355 LAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLK 534
           L +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE++D + 
Sbjct: 418 LGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFIS 477

Query: 535 YIASESTS 558
           Y+  E+T+
Sbjct: 478 YLQREATN 485

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 37/104 (35%), Positives = 63/104 (60%), Gaps = 3/104 (2%)
 Frame = +1

Query: 250 KNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-D 420
           +NF++ V+D      +L+EF+APWCGHCK LAP+YE  A +L     + +AK+D TAN +
Sbjct: 33  ENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL---KIVPLAKVDCTANTN 89

Query: 421 VPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
             + Y V+G+PT+      +     +Y+G R  D ++ ++  ++
Sbjct: 90  TCNKYGVSGYPTLKIF--RAGEEAGAYDGPRTADGIVSHLKKQA 131
>sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 precursor (Disulfide isomerase
           ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
           (HIP-70) (Q-2)
          Length = 505

 Score =  220 bits (561), Expect = 3e-57
 Identities = 106/188 (56%), Positives = 139/188 (73%), Gaps = 2/188 (1%)
 Frame = +1

Query: 1   FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMAEVFTME--AFEKFINDFLN 174
           FA+++ +  SHELS+FG+ES       +  R  K +KF M E F+ +  A E+F+ ++ +
Sbjct: 299 FAVASRKTFSHELSDFGLESTTGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQEYFD 358

Query: 175 EQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEE 354
             +  YLKSE IPE N+ PVKVVVA++FD +VN   KDVLIEFYAPWCGHCK+L PKY+E
Sbjct: 359 GNLKRYLKSEPIPETNEGPVKVVVAESFDDIVNAEDKDVLIEFYAPWCGHCKNLEPKYKE 418

Query: 355 LAKKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLK 534
           L +KLS + +IVIAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE++D + 
Sbjct: 419 LGEKLSKDPNIVIAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFIS 478

Query: 535 YIASESTS 558
           Y+  E+T+
Sbjct: 479 YLQREATN 486

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 43/127 (33%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
 Frame = +1

Query: 181 VPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEE 354
           V + L S  +   +D  V  +  +NF++ V+D      +L+EF+APWCGHCK LAP+YE 
Sbjct: 12  VALLLASALLASASD--VLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEA 69

Query: 355 LAKKLSGESDIVIAKMDATAN-DVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDML 531
            A +L G   + +AK+D TAN +  + Y V+G+PT+       +    +Y+G R  D ++
Sbjct: 70  AATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIV 125

Query: 532 KYIASES 552
            ++  ++
Sbjct: 126 SHLKKQA 132
>sp|P38658|ERP60_SCHMA Probable protein disulfide-isomerase ER-60 precursor (ERP60)
          Length = 484

 Score =  207 bits (527), Expect = 2e-53
 Identities = 100/202 (49%), Positives = 144/202 (71%)
 Frame = +1

Query: 1   FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMAEVFTMEAFEKFINDFLNEQ 180
           FA S + + S+E+S++GIE+   +K+  V    K++K+K+ E F+++AF  F+N F +  
Sbjct: 287 FAYSFADDFSYEISDYGIEA---DKLPAVVIQSKDKKYKL-EKFSLDAFSDFLNKFEDGL 342

Query: 181 VPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELA 360
           +  ++KSE +P  +   VK +VA NFD +VN+  KDV++ F+A WCGHCK+L PKYEE A
Sbjct: 343 LTPHVKSEPLPTDDSSAVKKLVALNFDEIVNNEEKDVMVVFHAGWCGHCKNLMPKYEEAA 402

Query: 361 KKLSGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYI 540
            K+  E ++V+A MDATANDVPSPY+V GFPTIYF PK  K+SP SY GGR+ +D++KY+
Sbjct: 403 SKVKNEPNLVLAAMDATANDVPSPYQVRGFPTIYFVPKGKKSSPVSYEGGRDTNDIIKYL 462

Query: 541 ASESTSSLKSYDRQGRVRKSDL 606
           A E+T  L  YDR G  +KS+L
Sbjct: 463 AREATEELIGYDRSGNPKKSEL 484

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 2/89 (2%)
 Frame = +1

Query: 292 LIEFYAPWCGHCKSLAPKYEELAKKLSGE-SDIVIAKMDATAND-VPSPYEVTGFPTIYF 465
           L++FYAPWCGHCK LAP++   A+ +SG+ +D+ + K+D T  + + S + V+G+PT+  
Sbjct: 38  LVKFYAPWCGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQESICSEFGVSGYPTLKI 97

Query: 466 APKNSKNSPKSYNGGREVDDMLKYIASES 552
                 +    YNG R  + +  Y+ S +
Sbjct: 98  FRNGDLDG--EYNGPRNANGIANYMISRA 124
>sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
          Length = 645

 Score =  174 bits (440), Expect = 3e-43
 Identities = 89/188 (47%), Positives = 120/188 (63%), Gaps = 3/188 (1%)
 Frame = +1

Query: 1    FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMA-EVFTMEAFEKFINDFLNE 177
            FAI++ ++ + E+ + G+ S     V     DE  +KF M  E F  +   +F+  F   
Sbjct: 450  FAIADEEDYAGEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKG 508

Query: 178  QVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEEL 357
            ++   +KS+ +P+ N  PVKVVV K FD++V DP KDVLIEFYAPWCGHCK L P Y  L
Sbjct: 509  KLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSL 568

Query: 358  AKKLSGESDIVIAKMDATANDVPSP-YEVTGFPTIYFAPKNSKNSPKSYNGG-REVDDML 531
            AKK  G+  +VIAKMDATANDVPS  Y+V GFPTIYFAP   K +P  + GG R+++ + 
Sbjct: 569  AKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLS 628

Query: 532  KYIASEST 555
            K+I   +T
Sbjct: 629  KFIEEHAT 636

 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 51/111 (45%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
 Frame = +1

Query: 226 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 402
           E   V+  +NFD +VND    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+
Sbjct: 177 EVTLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235

Query: 403 DATA-NDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
           DATA  D+   ++V+G+PT+       K  P  YNG RE   ++ Y+  +S
Sbjct: 236 DATAETDLAKRFDVSGYPTLKIF---RKGRPYDYNGpreKYGIVDYMIEQS 283

 Score = 76.6 bits (187), Expect = 6e-14
 Identities = 47/122 (38%), Positives = 70/122 (57%), Gaps = 3/122 (2%)
 Frame = +1

Query: 196 KSETIPEKNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKLS 372
           + + +  K +  V V+   NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L 
Sbjct: 52  EEDDLEVKEENGVLVLNDANFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIANILK 109

Query: 373 G-ESDIVIAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIAS 546
             +  I +AK+DAT A+ + S ++V+G+PTI       K     Y G R  ++++  +  
Sbjct: 110 DKDPPIPVAKIDATSASVLASRFDVSGYPTIKIL---KKGQAVDYEGSRTQEEIVAKVRE 166

Query: 547 ES 552
            S
Sbjct: 167 VS 168
>sp|P38659|PDIA4_RAT Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
            (Calcium-binding protein 2) (CaBP2)
          Length = 643

 Score =  171 bits (432), Expect = 2e-42
 Identities = 87/188 (46%), Positives = 121/188 (64%), Gaps = 3/188 (1%)
 Frame = +1

Query: 1    FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMA-EVFTMEAFEKFINDFLNE 177
            FAI++ ++ + E+ + G+ S     V     DE  +KF M  E F  +A ++F+  F   
Sbjct: 448  FAIADEEDYATEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDALQEFVMAFKKG 506

Query: 178  QVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEEL 357
            ++   +KS+ +P+ N  PV+VVV K FDA+V DP KDVLIEFYAPWCGHCK L P Y  L
Sbjct: 507  KLKPVIKSQPVPKNNKGPVRVVVGKTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPVYTSL 566

Query: 358  AKKLSGESDIVIAKMDATANDVPSP-YEVTGFPTIYFAPKNSKNSPKSYNGG-REVDDML 531
             KK  G+ D+VIAKMDATAND+ +  Y+V GFPTIYFAP   K +P  + GG R+++ + 
Sbjct: 567  GKKYKGQKDLVIAKMDATANDITNDRYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLS 626

Query: 532  KYIASEST 555
            K+I   +T
Sbjct: 627  KFIDEHAT 634

 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 48/111 (43%), Positives = 69/111 (62%), Gaps = 2/111 (1%)
 Frame = +1

Query: 226 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 402
           E    +  +NFD +VN+    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+
Sbjct: 175 EVTLTLTKENFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 233

Query: 403 DAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
           DAT   D+   ++V+G+PT+       K  P  YNG RE   ++ Y+  +S
Sbjct: 234 DATEQTDLAKRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMVEQS 281

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 47/115 (40%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
 Frame = +1

Query: 217 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 390
           K +  V V+  +NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L   +  I 
Sbjct: 57  KEENGVWVLNDENFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 114

Query: 391 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
           +AK+DAT A+ + S ++V+G+PTI       K     Y+G R  ++++  +   S
Sbjct: 115 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 166
>sp|P08003|PDIA4_MOUSE Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
          Length = 638

 Score =  170 bits (430), Expect = 4e-42
 Identities = 87/188 (46%), Positives = 119/188 (63%), Gaps = 3/188 (1%)
 Frame = +1

Query: 1    FAISNSQEQSHELSEFGIESPDSNKVYIVARDEKNQKFKMA-EVFTMEAFEKFINDFLNE 177
            FAI++ ++ + E+ + G+ S     V     DE  +KF M  E F  +   +F+  F   
Sbjct: 443  FAIADEEDYATEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKG 501

Query: 178  QVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEEL 357
            ++   +KS+ +P+ N  PVKVVV K FDA+V DP KDVLIEFYAPWCGHCK L P Y  L
Sbjct: 502  KLKPVIKSQPVPKNNKGPVKVVVGKTFDAIVMDPKKDVLIEFYAPWCGHCKQLEPIYTSL 561

Query: 358  AKKLSGESDIVIAKMDATANDVPS-PYEVTGFPTIYFAPKNSKNSPKSYNGG-REVDDML 531
             KK  G+ D+VIAKMDATAND+ +  Y+V GFPTIYFAP   K +P  + GG R+++ + 
Sbjct: 562  GKKYKGQKDLVIAKMDATANDITNDQYKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLS 621

Query: 532  KYIASEST 555
            K+I   +T
Sbjct: 622  KFIDEHAT 629

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 2/102 (1%)
 Frame = +1

Query: 253 NFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKMDAT-ANDVP 426
           NFD +VN+    +L+EFYAPWCGHCK LAP+YE+ AK+LS  S  I +AK+DAT   D+ 
Sbjct: 179 NFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLA 237

Query: 427 SPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
             ++V+G+PT+       K  P  YNG RE   ++ Y+  +S
Sbjct: 238 KRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMIEQS 276

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 3/115 (2%)
 Frame = +1

Query: 217 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 390
           K +  V V+   NFD  V D  KD VL+EFYAPWCGHCK  AP+YE++A  L   +  I 
Sbjct: 52  KEENGVWVLNDGNFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 109

Query: 391 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 552
           +AK+DAT A+ + S ++V+G+PTI       K     Y+G R  ++++  +   S
Sbjct: 110 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 161
>sp|P55059|PDI_HUMIN Protein disulfide-isomerase precursor (PDI)
          Length = 505

 Score =  162 bits (409), Expect = 1e-39
 Identities = 84/165 (50%), Positives = 110/165 (66%), Gaps = 5/165 (3%)
 Frame = +1

Query: 64  DSNKVYIVARDEKNQKFKMAEV--FTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVK 237
           D    + +    KNQKF   +    T EA + F++DF+  ++   +KSE IPEK + PV 
Sbjct: 299 DKFPAFAIQEVAKNQKFPFDQEKEITFEAIKAFVDDFVAGKIEPSIKSEPIPEKQEGPVT 358

Query: 238 VVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELA---KKLSGESDIVIAKMDA 408
           VVVAKN++ +V D TKDVLIEFYAPWCGHCK+LAPKYEEL     K   +  +VIAK+DA
Sbjct: 359 VVVAKNYNEIVLDDTKDVLIEFYAPWCGHCKALAPKYEELGALYAKSEFKDRVVIAKVDA 418

Query: 409 TANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIA 543
           TANDVP   E+ GFPTI   P  +K  P +Y+G R V+D++K+IA
Sbjct: 419 TANDVPD--EIQGFPTIKLYPAGAKGQPVTYSGSRTVEDLIKFIA 461

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
 Frame = +1

Query: 289 VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDAT-ANDVPSPYEVTGFPTIYF 465
           VL EF+APWCGHCK+LAP+YEE A  L  E +I +AK+D T   D+   + V G+PT+  
Sbjct: 41  VLAEFFAPWCGHCKALAPEYEEAATTLK-EKNIKLAKVDCTEETDLCQQHGVEGYPTLKV 99

Query: 466 APKNSKNSPKSYNGGREVDDMLKYIASESTSSLK--SYDRQGRVRKSDL*KIKIVEY 630
                  SP  Y G R+   +  Y+  +S  ++   + D     +K+D  K  +V Y
Sbjct: 100 FRGLDNVSP--YKGQRKAAAITSYMIKQSLPAVSEVTKDNLEEFKKAD--KAVLVAY 152
>sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase A4 precursor (ERp-72 homolog)
          Length = 618

 Score =  156 bits (394), Expect = 6e-38
 Identities = 82/196 (41%), Positives = 115/196 (58%), Gaps = 4/196 (2%)
 Frame = +1

Query: 1    FAISNSQEQSHELSEFGI-ESPDSNKVYIVARDEKNQKFKMAEVFTM--EAFEKFINDFL 171
            FA+++ +E + EL E G+ +S   + V +   D K       E      E  E F+    
Sbjct: 421  FAVADEEEFAKELEELGLGDSGLEHNVVVFGYDGKKYPMNPDEFDGELDENLEAFMKQIS 480

Query: 172  NEQVPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYE 351
            + +   ++KS   P+ +  PVK VV  NFD +VND +KDVLIEFYAPWCGHCKS   KY 
Sbjct: 481  SGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYV 540

Query: 352  ELAKKL-SGESDIVIAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDM 528
            ELA+ L   + ++V+AKMDAT ND PS + V GFPTIYFAP   K+ P  Y+G R+++D+
Sbjct: 541  ELAQALKKTQPNVVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDL 600

Query: 529  LKYIASESTSSLKSYD 576
             K++      S +  D
Sbjct: 601  KKFMTKHGVKSFQKKD 616

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 51/131 (38%), Positives = 80/131 (61%), Gaps = 5/131 (3%)
 Frame = +1

Query: 190 YLKSETIPEKNDEPVKVVV--AKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAK 363
           +++S   P     P +VV    +NFD  +++  + VL+EFYAPWCGHCK LAP+YE+ A+
Sbjct: 133 WVESRVDPNYKPPPEEVVTLTTENFDDFISN-NELVLVEFYAPWCGHCKKLAPEYEKAAQ 191

Query: 364 KLSGE-SDIVIAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPK-SYNGGREVDDMLK 534
           KL  + S + + K+DAT   D+ + Y V+G+PT+    K  +N  +  YNG RE   ++K
Sbjct: 192 KLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTM----KIIRNGRRFDYNGpreAAGIIK 247

Query: 535 YIASESTSSLK 567
           Y+  +S  + K
Sbjct: 248 YMTDQSKPAAK 258

 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 48/116 (41%), Positives = 73/116 (62%), Gaps = 1/116 (0%)
 Frame = +1

Query: 223 DEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKM 402
           DE V V+  KNFDA +      VL++FYAPWCGHCK LAP+YE+ + K+S    I +AK+
Sbjct: 35  DEGVVVLTDKNFDAFLKK-NPSVLVKFYAPWCGHCKHLAPEYEKASSKVS----IPLAKV 89

Query: 403 DATA-NDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTSSLK 567
           DAT   ++   +E+ G+PT+ F  K+ K  P  Y+GGR+   +++++ S    + K
Sbjct: 90  DATVETELGKRFEIQGYPTLKFW-KDGK-GPNDYDGGRDEAGIVEWVESRVDPNYK 143
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,327,857
Number of Sequences: 369166
Number of extensions: 1608872
Number of successful extensions: 5177
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4871
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5081
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)