Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_I14
(908 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O02328|IF38_CAEEL Probable eukaryotic translation initia... 134 5e-31
sp|Q99613|IF38_HUMAN Eukaryotic translation initiation fact... 129 1e-29
sp|O14164|IF38_SCHPO Probable eukaryotic translation initia... 96 1e-19
sp|Q9XHM1|IF38_MEDTR Eukaryotic translation initiation fact... 87 6e-17
sp|O49160|IF38_ARATH Eukaryotic translation initiation fact... 86 2e-16
sp|P32497|IF38_YEAST Eukaryotic translation initiation fact... 74 7e-13
sp|Q49V33|Y2232_STAS1 Hypothetical ATP:guanido phosphotrans... 31 4.2
sp|O13799|YE02_SCHPO Putative helicase C17H9.02 31 5.5
sp|P15090|FABPA_HUMAN Fatty acid-binding protein, adipocyte... 30 9.3
sp|P04117|FABPA_MOUSE Fatty acid-binding protein, adipocyte... 30 9.3
>sp|O02328|IF38_CAEEL Probable eukaryotic translation initiation factor 3 subunit 8 (eIF3
p110) (eIF3c)
Length = 898
Score = 134 bits (336), Expect = 5e-31
Identities = 73/177 (41%), Positives = 104/177 (58%), Gaps = 4/177 (2%)
Frame = +1
Query: 10 KILTYHDFSSDKEVEYRDKLHYETKMMSLCSVVSDYLNKKN----YGDDEKCRVYMRQLE 177
KIL D S+ +Y +KL E M SL Y+ +N + E C+VYM ++E
Sbjct: 432 KILQNADCHSN---DYIEKLKAEKDMCSLIEKAEKYVELRNDSGIFDKHEVCKVYMMRIE 488
Query: 178 HIYYRFDPTVDIKEEIPSYKEMRRLSGYITSRDETDRLRTRAILCHIYYLALHDYWFEAR 357
H YY++ + E + K M L I + D+ RLR RA+LCH+YYLA+HD W AR
Sbjct: 489 HAYYKYQD----QNEEDAGKLMDYLCNKIYTLDDEKRLRQRAMLCHVYYLAVHDKWHRAR 544
Query: 358 DMMAMSALTNLIDRADASTQILFNRVTVQLGLCAFRRGCIKEAHQALAEFARVRQSE 528
D++ MS + ++D +D TQIL+NR QLGLCAFR G I+EAHQ L+E ++++
Sbjct: 545 DLLLMSHMQAIVDHSDVDTQILYNRTICQLGLCAFRHGFIREAHQGLSEIQNTQRAK 601
Score = 105 bits (263), Expect = 1e-22
Identities = 50/116 (43%), Positives = 77/116 (66%)
Frame = +2
Query: 506 LQGSGRVKEILAQGTRLNRNEATAEELYREKMFLQPYHKHINVDVIECAYLVSAMLTDVN 685
+Q + R KE+LAQ ++E TAE+ ++ PYH HINV+++EC YL+ +ML ++
Sbjct: 594 IQNTQRAKELLAQAVGTRQHEKTAEQEKIDRSRQVPYHMHINVELMECVYLICSMLLEIP 653
Query: 686 HCHMQQADGRRVMISRNFHYVLKNNDRTTLNGRPDNLKEHVVAASKALFNW*LENC 853
H + + RR M+SR+FHY LK +++ +L G P+N +EHVVAASKA+ N + C
Sbjct: 654 HMASCEFEMRRRMLSRSFHYQLKQSEKASLTGPPENTREHVVAASKAMLNGDWKKC 709
Score = 30.4 bits (67), Expect = 7.1
Identities = 13/30 (43%), Positives = 17/30 (56%)
Frame = +3
Query: 798 RNMLLQHQKLYLIGDWKTAADYIFDDKMKE 887
R ++ K L GDWK DYI +DKM +
Sbjct: 691 REHVVAASKAMLNGDWKKCQDYIVNDKMNQ 720
>sp|Q99613|IF38_HUMAN Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c)
Length = 913
Score = 129 bits (323), Expect = 1e-29
Identities = 75/185 (40%), Positives = 105/185 (56%), Gaps = 18/185 (9%)
Frame = +1
Query: 4 YTKILTYHDFSSDKEVEYRDKLHYETKMMSLCSVVSDYLNKKNYGDDEKCRVYMRQLEHI 183
+TKI+ D S + VE+ L E ++ ++ V YL +K +E CR+Y+ ++ H
Sbjct: 455 FTKIMQNTDPHSQEYVEH---LKDEAQVCAIIERVQRYLEEKGT-TEEVCRIYLLRILHT 510
Query: 184 YYRFDPTVDIKEEIP------------------SYKEMRRLSGYITSRDETDRLRTRAIL 309
YY+FD ++ P S M RL YI ++D TDR+RT AIL
Sbjct: 511 YYKFDYKAHQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAIL 570
Query: 310 CHIYYLALHDYWFEARDMMAMSALTNLIDRADASTQILFNRVTVQLGLCAFRRGCIKEAH 489
CHIY+ ALH W++ARD+M MS L + I AD QIL+NR VQLG+CAFR+G K+AH
Sbjct: 571 CHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAH 630
Query: 490 QALAE 504
AL +
Sbjct: 631 NALLD 635
Score = 97.4 bits (241), Expect = 5e-20
Identities = 49/110 (44%), Positives = 73/110 (66%), Gaps = 1/110 (0%)
Frame = +2
Query: 503 NLQGSGRVKEILAQGTRLNR-NEATAEELYREKMFLQPYHKHINVDVIECAYLVSAMLTD 679
++Q SGR KE+L QG L E E+ E+ P+H HIN++++EC YLVSAML +
Sbjct: 635 DIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLE 694
Query: 680 VNHCHMQQADGRRVMISRNFHYVLKNNDRTTLNGRPDNLKEHVVAASKAL 829
+ + ++D RR MIS+ FH+ L+ +R L G P++++EHVVAASKA+
Sbjct: 695 IPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAM 744
>sp|O14164|IF38_SCHPO Probable eukaryotic translation initiation factor 3 93 kDa subunit
(eIF3 p93)
Length = 918
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/172 (34%), Positives = 89/172 (51%), Gaps = 19/172 (11%)
Frame = +1
Query: 52 EYRDKLHYETKMMSLCSVVSDYLNKKNYGDDEKCRVYMRQLEHIYYRFDPTVDIKEEIPS 231
EY D+L ET + +L YL + ++ R+ MR+L+ +YY+ + + EE+
Sbjct: 475 EYIDRLKDETSLYTLLVRSQGYLERIGVVENT-ARLIMRRLDRVYYKPEQVIRANEEVAW 533
Query: 232 YKEMRRLSGYITSRDETDR-------------------LRTRAILCHIYYLALHDYWFEA 354
IT R T LRTRA+LCHIY+ AL + +++A
Sbjct: 534 RSFPPTFDLTITPRATTTTPDILIHSLCVYLYNNGVSLLRTRAMLCHIYHEALQNRFYKA 593
Query: 355 RDMMAMSALTNLIDRADASTQILFNRVTVQLGLCAFRRGCIKEAHQALAEFA 510
RDM+ MS L + + AD +TQIL NR VQ+GLCAFR G ++E AL + +
Sbjct: 594 RDMLLMSHLQDSVHAADIATQILHNRTMVQIGLCAFRNGMVQETQYALQDIS 645
Score = 75.5 bits (184), Expect = 2e-13
Identities = 40/114 (35%), Positives = 69/114 (60%), Gaps = 4/114 (3%)
Frame = +2
Query: 500 QNLQGSGRVKEILAQGTRLNR-NEATAEELYREKMFLQPYHKHINVDVIECAYLVSAMLT 676
Q++ +GRVKE+L QG + + + T ++ +K + P+H HIN++++EC YL +ML
Sbjct: 642 QDISTTGRVKELLGQGIQAPKFGQFTPDQDRLDKQLVLPFHMHINLELLECVYLTCSMLM 701
Query: 677 DV---NHCHMQQADGRRVMISRNFHYVLKNNDRTTLNGRPDNLKEHVVAASKAL 829
++ +D R+ +ISR F +L+ DR G P+N +E+++ ASKAL
Sbjct: 702 EIPAMAAASSTASDSRKRVISRPFRRMLEYIDRQLFVGPPENTREYIMQASKAL 755
>sp|Q9XHM1|IF38_MEDTR Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c)
Length = 935
Score = 87.0 bits (214), Expect = 6e-17
Identities = 44/111 (39%), Positives = 71/111 (63%), Gaps = 1/111 (0%)
Frame = +2
Query: 506 LQGSGRVKEILAQGTRLNR-NEATAEELYREKMFLQPYHKHINVDVIECAYLVSAMLTDV 682
L GRVKE+LAQG +R +E T E+ E+ PYH HIN++++E +L SAML +V
Sbjct: 587 LYSGGRVKELLAQGVSQSRYHEKTPEQERLERRRQMPYHMHINLELLESVHLTSAMLLEV 646
Query: 683 NHCHMQQADGRRVMISRNFHYVLKNNDRTTLNGRPDNLKEHVVAASKALFN 835
+ D +R +IS+NF +L+ +++ T G P+ +++HV+AA++ L N
Sbjct: 647 PNMAANVHDAKRKIISKNFRRLLEVSEKQTFTGPPETVRDHVMAATRVLIN 697
Score = 78.6 bits (192), Expect = 2e-14
Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 43/194 (22%)
Frame = +1
Query: 52 EYRDKLHYETKMMSLCSVVSDYLNKKNYGDDE-KCRVYMRQLEHIYYR------------ 192
EY ++L E + + L V +YL ++ GD + +V ++++E IYY+
Sbjct: 395 EYVERLRDEPQFVVLAQNVQEYL--ESIGDFKASSKVALKRVELIYYKPHEVYEATRKLA 452
Query: 193 --------------------------FDPTVDIKEEIPSYKE-MRRLSGYITS---RDET 282
F T+++ P++ E R L + S +
Sbjct: 453 EMTVEGDNGEMSEEPKGFEDTRIPAPFVVTLELVARKPTFPENSRTLMDVLVSLIYKYGD 512
Query: 283 DRLRTRAILCHIYYLALHDYWFEARDMMAMSALTNLIDRADASTQILFNRVTVQLGLCAF 462
+R + RA+LC IY+ AL D + ARD++ MS L + D STQILFNR QLGLCAF
Sbjct: 513 ERTKARAMLCDIYHHALLDEFAVARDLLLMSHLQENVHHMDISTQILFNRAMSQLGLCAF 572
Query: 463 RRGCIKEAHQALAE 504
R G + EAH L+E
Sbjct: 573 RAGLVSEAHGCLSE 586
>sp|O49160|IF38_ARATH Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110)
(eIF3c) (p105)
Length = 900
Score = 85.5 bits (210), Expect = 2e-16
Identities = 66/198 (33%), Positives = 93/198 (46%), Gaps = 41/198 (20%)
Frame = +1
Query: 52 EYRDKLHYETKMMSLCSVVSDYLNKKNYGDDEKC-RVYMRQLEHIYYRFDPTVD------ 210
EY ++L E ++L + DY + GD + +V +R++E IYY+ D
Sbjct: 380 EYVERLRDEPMFLALAQNIQDYFERM--GDFKAAAKVALRRVEAIYYKPQEVYDAMRKLA 437
Query: 211 -IKEEIPSYKEMRRLSGYITS------------------------------RDETDRLRT 297
+ EE +E + SG TS R+ +R +
Sbjct: 438 ELVEEEEETEEAKEESGPPTSFIVVPEVVPRKPTFPESSRAMMDILVSLIYRNGDERTKA 497
Query: 298 RAILCHIYYLALHDYWFEARDMMAMSALTNLIDRADASTQILFNRVTVQLGLCAFRRGCI 477
RA+LC I + AL D + ARD++ MS L + I D STQILFNR QLGLCAFR G I
Sbjct: 498 RAMLCDINHHALMDNFVTARDLLLMSHLQDNIQHMDISTQILFNRTMAQLGLCAFRAGMI 557
Query: 478 KEAHQALAEF---ARVRQ 522
E+H L+E RVR+
Sbjct: 558 TESHSCLSELYSGQRVRE 575
Score = 80.9 bits (198), Expect = 5e-15
Identities = 40/109 (36%), Positives = 69/109 (63%), Gaps = 1/109 (0%)
Frame = +2
Query: 506 LQGSGRVKEILAQGTRLNR-NEATAEELYREKMFLQPYHKHINVDVIECAYLVSAMLTDV 682
L RV+E+LAQG +R +E T E+ E+ PYH H+N++++E +L+ AML +V
Sbjct: 567 LYSGQRVRELLAQGVSQSRYHEKTPEQERMERRRQMPYHMHLNLELLEAVHLICAMLLEV 626
Query: 683 NHCHMQQADGRRVMISRNFHYVLKNNDRTTLNGRPDNLKEHVVAASKAL 829
+ D +R +IS+NF +L+ ++R P+N+++HV+AA++AL
Sbjct: 627 PNMAANSHDAKRRVISKNFRRLLEISERQAFTAPPENVRDHVMAATRAL 675
>sp|P32497|IF38_YEAST Eukaryotic translation initiation factor 3 93 kDa subunit (eIF3
p93) (Nuclear transport protein NIP1)
Length = 812
Score = 73.6 bits (179), Expect = 7e-13
Identities = 54/184 (29%), Positives = 86/184 (46%), Gaps = 22/184 (11%)
Frame = +1
Query: 13 ILTYHDFSSDKEVEYRDKLHYETKMMSLCSVVSDYLNKKNYGDDEKCRVYMRQLEHIYYR 192
+L SSD + RD+ ++ L ++ + R ++++L+HIYY+
Sbjct: 384 LLNIDPHSSDYLIRLRDEQSIYNLILRTQLYFEATLKDEHDLERALTRPFVKRLDHIYYK 443
Query: 193 FDPTVDIKEEIPSYKEMRRLSGYITSRDETDR----------------------LRTRAI 306
+ + I E + TS+D+ D ++ RAI
Sbjct: 444 SENLIKIMETAAWNIIPAQFKSKFTSKDQLDSADYVDNLIDGLSTILSKQNNIAVQKRAI 503
Query: 307 LCHIYYLALHDYWFEARDMMAMSALTNLIDRADASTQILFNRVTVQLGLCAFRRGCIKEA 486
L +IYY AL+ + A+DM+ S + I++ D+S QILFNRV VQLGL AF+ I+E
Sbjct: 504 LYNIYYTALNKDFQTAKDMLLTSQVQTNINQFDSSLQILFNRVVVQLGLSAFKLCLIEEC 563
Query: 487 HQAL 498
HQ L
Sbjct: 564 HQIL 567
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/127 (27%), Positives = 71/127 (55%), Gaps = 11/127 (8%)
Frame = +2
Query: 491 KLWQNLQGSGRVKEILAQGTRLNR------NEATAEELYREKMFLQPYHKHINVDVIECA 652
++ +L S ++EIL Q + L+R N A+A+E R+ + PYH+HIN+D+I+
Sbjct: 565 QILNDLLSSSHLREILGQQS-LHRISLNSSNNASADERARQCL---PYHQHINLDLIDVV 620
Query: 653 YLVSAMLTDVNH--CHMQQADGRRVMIS-RNFHYVLKNNDRTTLNGRPDNLKEHVVAASK 823
+L ++L ++ +R+ S ++ L++ D+ + G P+ L+++V+ A+K
Sbjct: 621 FLTCSLLIEIPRMTAFYSGIKVKRIPYSPKSIRRSLEHYDKLSFQGPPETLRDYVLFAAK 680
Query: 824 AL--FNW 838
++ NW
Sbjct: 681 SMQKGNW 687
>sp|Q49V33|Y2232_STAS1 Hypothetical ATP:guanido phosphotransferase SSP2232
Length = 336
Score = 31.2 bits (69), Expect = 4.2
Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Frame = +2
Query: 461 SEEDVLKKPTKLWQNLQGSGRVKEILAQGTRLNRNE--ATAEELYREKMFLQPYHKHINV 634
+EED+++ +++ Q + + E + RLNR+ T + +YR L+ Y + I++
Sbjct: 223 TEEDIIESLSEVVQQI-----INEEMQIRERLNRHNYTETLDRVYRSLGILK-YSRLISM 276
Query: 635 DVIECAYLVSAMLTDVNHCHMQQADGRRVMISRNFHYVLKNNDRTTLNG-RPDNLKEHV 808
+ + D+ + ++ +M++ ++L + D T+N R D L+EH+
Sbjct: 277 EEASLRLSEVKLGIDLEYIELEDFKFNELMVAIQSPFLLDDEDDRTVNEKRADILREHI 335
>sp|O13799|YE02_SCHPO Putative helicase C17H9.02
Length = 1030
Score = 30.8 bits (68), Expect = 5.5
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Frame = +2
Query: 458 LSEEDVLKKPTKLWQNLQGSGRVKEILAQ----GTRLN-RNEATAEELYREKMFLQPYHK 622
+S ED+LKK +QN++ +KE L Q T +N NE +E + K+ L+ Y +
Sbjct: 563 ISPEDILKKSFYQFQNMESLPLIKEELMQLKNEETSINIPNETAVKEFHDLKLQLEKYGE 622
Query: 623 HI 628
I
Sbjct: 623 EI 624
>sp|P15090|FABPA_HUMAN Fatty acid-binding protein, adipocyte (AFABP) (Adipocyte
lipid-binding protein) (ALBP) (A-FABP)
Length = 132
Score = 30.0 bits (66), Expect = 9.3
Identities = 11/23 (47%), Positives = 15/23 (65%)
Frame = +3
Query: 834 IGDWKTAADYIFDDKMKEISMGF 902
+G WK + FDD MKE+ +GF
Sbjct: 6 VGTWKLVSSENFDDYMKEVGVGF 28
>sp|P04117|FABPA_MOUSE Fatty acid-binding protein, adipocyte (AFABP) (Adipocyte
lipid-binding protein) (ALBP) (A-FABP) (P2 adipocyte
protein) (Myelin P2 protein homolog) (3T3-L1 lipid
binding protein) (422 protein) (P15)
Length = 132
Score = 30.0 bits (66), Expect = 9.3
Identities = 11/23 (47%), Positives = 15/23 (65%)
Frame = +3
Query: 834 IGDWKTAADYIFDDKMKEISMGF 902
+G WK + FDD MKE+ +GF
Sbjct: 6 VGTWKLVSSENFDDYMKEVGVGF 28
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,640,635
Number of Sequences: 369166
Number of extensions: 2096361
Number of successful extensions: 6317
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6088
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6309
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9222552960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)