Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_I09
(804 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O94446|MST1_SCHPO Protein mst1 40 0.007
sp|Q96D71|REPS1_HUMAN RalBP1 associated Eps domain containi... 38 0.028
sp|O54916|REPS1_MOUSE RalBP1 associated Eps domain containi... 38 0.028
sp|Q80XA6|REPS2_MOUSE RalBP1 associated Eps domain containi... 38 0.028
sp|Q8NFH8|REPS2_HUMAN RalBP1 associated Eps domain containi... 37 0.048
sp|O17972|NPHP1_CAEEL Nephrocystin-1-like protein 36 0.11
sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G) 34 0.53
sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-... 33 0.91
sp|Q90763|CADH7_CHICK Cadherin-7 precursor 33 1.2
sp|Q62245|SOS1_MOUSE Son of sevenless protein homolog 1 (SO... 32 1.6
>sp|O94446|MST1_SCHPO Protein mst1
Length = 463
Score = 40.0 bits (92), Expect = 0.007
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Frame = -3
Query: 640 DNETISSFIK---PEGPKKLLIEGESSTAVNNMDSQDSITDTTKLE--TDVVMKTPPVPP 476
DN +S I+ PE PKK +G+SS +D + SIT +K E T K P P
Sbjct: 70 DNIDLSKGIEYPPPEKPKKAHGKGKSSKRPKAVDRRRSITAPSKTEPSTPSTEKPEPSTP 129
Query: 475 RHRWSHKPIENSNSFSTFEEDAPPNEPLLDKQYLVNKSAFGIDFSQSP--VAIVMSLNSI 302
H + S EED P L K+ V + F Q+P +A + ++N I
Sbjct: 130 SGESDHGSNAGNESLPLLEEDHKPES--LSKEQEVERLRFSGSMVQNPHEIARIRNINKI 187
Query: 301 LDIDDRKEAYNY 266
D E + +
Sbjct: 188 CIGDHEIEPWYF 199
>sp|Q96D71|REPS1_HUMAN RalBP1 associated Eps domain containing protein 1
(RalBP1-interacting protein 1)
Length = 744
Score = 38.1 bits (87), Expect = 0.028
Identities = 19/51 (37%), Positives = 30/51 (58%)
Frame = -3
Query: 283 KEAYNYLISTTKMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMPLNY 131
K+A I K L LN E+ + LK + ++RISLE+QLE++ P ++
Sbjct: 693 KKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSH 743
>sp|O54916|REPS1_MOUSE RalBP1 associated Eps domain containing protein 1
(RalBP1-interacting protein 1)
Length = 743
Score = 38.1 bits (87), Expect = 0.028
Identities = 19/51 (37%), Positives = 30/51 (58%)
Frame = -3
Query: 283 KEAYNYLISTTKMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMPLNY 131
K+A I K L LN E+ + LK + ++RISLE+QLE++ P ++
Sbjct: 692 KKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLEVQLEQLRPFSH 742
>sp|Q80XA6|REPS2_MOUSE RalBP1 associated Eps domain containing protein 2
(RalBP1-interacting protein 2) (Partner of RalBP1)
Length = 521
Score = 38.1 bits (87), Expect = 0.028
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Frame = -3
Query: 409 PPNEPLLDKQYLVNKSAFGIDFSQSPVAIVMSLNSILDI----------DDRKEAYNYLI 260
PP++P+ K N++ SQ P A V S + +K+A I
Sbjct: 422 PPSKPIRRKFRPENQTTE----SQEPAAAVGGAVSAAMVKPHPTVQKQSSKQKKAIQTAI 477
Query: 259 STTKMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMPL 137
K L LN E+ + LK++ Q+RI+LE QLE++ P+
Sbjct: 478 RKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPV 518
>sp|Q8NFH8|REPS2_HUMAN RalBP1 associated Eps domain containing protein 2
(RalBP1-interacting protein 2) (Partner of RalBP1)
Length = 660
Score = 37.4 bits (85), Expect = 0.048
Identities = 19/50 (38%), Positives = 30/50 (60%)
Frame = -3
Query: 286 RKEAYNYLISTTKMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMPL 137
+K+A I K L LN E+ + LK++ Q+RI+LE QLE++ P+
Sbjct: 608 QKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPV 657
>sp|O17972|NPHP1_CAEEL Nephrocystin-1-like protein
Length = 682
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Frame = -3
Query: 661 PFKPALYDNETISSFIKPEGPKKLLIEGESSTAVNNMDSQDSITDTTKLETDVVMKTP-- 488
P K L + ++ S + E PK I ST N+ +S+DS D+ +ETDV + P
Sbjct: 94 PEKEQLSFSVSVDSQSEEEKPKMAAIGRRKSTMYNDDESEDSDNDSEIIETDVQLDDPLP 153
Query: 487 --PVPPRHR 467
P PP+ +
Sbjct: 154 SQPQPPQQQ 162
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 33.9 bits (76), Expect = 0.53
Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 3/157 (1%)
Frame = -3
Query: 601 PKKLLIEGESSTAVNNMDSQDSITDTTKLETDVVMKTPPVPPRHRWSHKPIENSNSFSTF 422
P +L + G ++ + S+ DT K+ T+ M T V +H+ + N +
Sbjct: 789 PNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNEVLDMSD 848
Query: 421 EEDAPPNEP--LLDKQYLVNKSAFGIDFSQSPVAIVMSLNSILDI-DDRKEAYNYLISTT 251
+E N P L D +Y+ + G D + + ++ DD A Y+ +
Sbjct: 849 DEVRKANAPEMLSDGEYISDVEE-GEDAMTGDTDKYLGPQDLKELGDDSLPAEGYMGFSL 907
Query: 250 KMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMP 140
+ SL S + + S L + R S+ I+ E ++P
Sbjct: 908 GARSASLRSFSSDRSYTLNRSSYARDSMMIE-ELLVP 943
>sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-associated, coiled-coil
containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2)
Length = 1388
Score = 33.1 bits (74), Expect = 0.91
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 7/56 (12%)
Frame = -3
Query: 298 DIDDRKEAYNYLISTTKMQ-------CESLTSLNQEMSRNLKQLQQQRISLEIQLE 152
++ D+ EA Y + K Q CE T L +E+ + ++LQ +R SL QLE
Sbjct: 861 ELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLE 916
>sp|Q90763|CADH7_CHICK Cadherin-7 precursor
Length = 785
Score = 32.7 bits (73), Expect = 1.2
Identities = 40/180 (22%), Positives = 67/180 (37%), Gaps = 9/180 (5%)
Frame = -3
Query: 646 LYDNETISSFIKPEGPKKLLIEGESSTAVNNMDSQDSITDTTKL--ETDVVMKTPPVPPR 473
LY + S K +G K ++ GE ++++ +D TK + T
Sbjct: 66 LYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQAH 125
Query: 472 HRWSHKPIENSNSFSTFEEDAPPNEP-LLDKQYLVNKSAFGIDFSQSPVAIVMSLNSILD 296
R ++KP+E + F +D NEP LD Y SPV + + D
Sbjct: 126 DRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP------EMSPVGTSVVQVTATD 179
Query: 295 IDD------RKEAYNYLISTTKMQCESLTSLNQEMSRNLKQLQQQRISLEIQLEKMMPLN 134
DD + Y+ L E T + + N+ + + + L IQ + M+ N
Sbjct: 180 ADDPTYGNSARVVYSILQGQPYFSVEPKTGIIKTALPNMDREAKDQYLLVIQAKDMVGQN 239
>sp|Q62245|SOS1_MOUSE Son of sevenless protein homolog 1 (SOS-1) (mSOS-1)
Length = 1319
Score = 32.3 bits (72), Expect = 1.6
Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 18/116 (15%)
Frame = -3
Query: 688 EGDKISYPVPFKPALYDNETISSFIKPEGPKKLLIEGESSTAVNNMD------------- 548
E KISY + ++ET S+ P P+ L +S +N D
Sbjct: 1059 EPRKISYS-----RIPESETESTASAPNSPRTPLTPPPASGTSSNTDVCSVFDSDHSASP 1113
Query: 547 --SQDSITDTTKLE--TDVVMKTPPVPPRHRWSHKPIENSNS-FSTFEEDAPPNEP 395
S+ + + L TD V PPVPPR R P E+S S + D+PP P
Sbjct: 1114 FHSRSASVSSISLSKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIP 1169
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,437,486
Number of Sequences: 369166
Number of extensions: 1667388
Number of successful extensions: 4852
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4689
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4846
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)