Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_G12
(885 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 359 6e-99
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 357 3e-98
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 352 6e-97
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 352 8e-97
sp|Q27257|DIF1_CAEEL Protein dif-1 317 2e-86
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 316 6e-86
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 193 5e-49
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 161 2e-39
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 160 6e-39
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 158 2e-38
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 359 bits (921), Expect = 6e-99
Identities = 175/267 (65%), Positives = 203/267 (76%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C V VG PLDT+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGV
Sbjct: 23 CLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGV 82
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQG 362
TPMFAVCFFG+ LG+KLQ K L+ PQ+FAAGMLSGVFTT IMTPGERIKCLLQ+Q
Sbjct: 83 TPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQA 142
Query: 363 ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 542
+S E KY G D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEWLK I TPEG
Sbjct: 143 SSGES-KYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEG 201
Query: 543 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEG 722
S LS R L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG
Sbjct: 202 KRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEG 261
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGYE 803
+ LY+G + V+IRAFPANAACFLG+E
Sbjct: 262 VTSLYKGFNAVMIRAFPANAACFLGFE 288
Score = 63.2 bits (152), Expect = 1e-09
Identities = 37/86 (43%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Frame = +3
Query: 558 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 722
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGY 800
I GLYRG++ +I P A CF G+
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGF 93
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +3
Query: 15 VGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMF 194
V P D LK R Q P PG+ P G D + + +EG YKG A +I P
Sbjct: 226 VAIPPDVLKSRFQTAP---PGKYP--NGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPAN 280
Query: 195 AVCFFGYNLGRK 230
A CF G+ + K
Sbjct: 281 AACFLGFEVAMK 292
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 357 bits (915), Expect = 3e-98
Identities = 173/267 (64%), Positives = 203/267 (76%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C V VG PLDT+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGV
Sbjct: 23 CLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPIIGV 82
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQG 362
TPMFAVCFFG+ LG+KLQ K L+ PQ+FAAGMLSG+FTT IMTPGERIKCLLQ+Q
Sbjct: 83 TPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQA 142
Query: 363 ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 542
+S E KY G D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEW+K I TPEG
Sbjct: 143 SSGET-KYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPEG 201
Query: 543 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEG 722
S LS R L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG
Sbjct: 202 KRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEG 261
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGYE 803
+ LY+G + V+IRAFPANAACFLG+E
Sbjct: 262 VTSLYKGFNAVMIRAFPANAACFLGFE 288
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/86 (43%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Frame = +3
Query: 558 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 722
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREG 67
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGY 800
I GLYRG++ +I P A CF G+
Sbjct: 68 IRGLYRGMAAPIIGVTPMFAVCFFGF 93
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +3
Query: 15 VGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMF 194
V P D LK R Q P PG+ P G D + + +EG YKG A +I P
Sbjct: 226 VAIPPDVLKSRFQTAP---PGKYP--NGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPAN 280
Query: 195 AVCFFGYNLGRK 230
A CF G+ + K
Sbjct: 281 AACFLGFEVAMK 292
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 352 bits (904), Expect = 6e-97
Identities = 169/267 (63%), Positives = 199/267 (74%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C V VG PLDT+KVRLQ P PG+PP+Y G +DCF +TL EG G Y+GMAAP+IGV
Sbjct: 23 CLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIGV 82
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQG 362
TPMFAVCFFG+ LG++LQ K LT PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q
Sbjct: 83 TPMFAVCFFGFGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQ- 141
Query: 363 ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 542
AS KY G D +KLY+E GIR YKGTA TL+RD+PA+G YFM+YEWLK + TP+G
Sbjct: 142 ASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQG 201
Query: 543 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEG 722
LS R L AGG G+ NW+V IPPD LKSR QTAP GKYP+G R V RE++ EG
Sbjct: 202 KSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEG 261
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGYE 803
+ LY+G + V+IRAFPANAACFLG+E
Sbjct: 262 VTSLYKGFNAVMIRAFPANAACFLGFE 288
Score = 73.2 bits (178), Expect = 9e-13
Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 2/149 (1%)
Frame = +3
Query: 90 YKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENT--PLT 263
Y G +DC + G GFYKG A L+ P + F Y + L + L+
Sbjct: 149 YSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLS 208
Query: 264 KPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSI 443
P++ AG G+F + P + +K Q K P ++ DV+R+L +E G+ S+
Sbjct: 209 VPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFR---DVLRELIREEGVTSL 265
Query: 444 YKGTAATLLRDIPATGTYFMSYEWLKEIL 530
YKG A ++R PA F+ +E +IL
Sbjct: 266 YKGFNAVMIRAFPANAACFLGFEIPMKIL 294
Score = 63.2 bits (152), Expect = 1e-09
Identities = 37/86 (43%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Frame = +3
Query: 558 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 722
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGY 800
I GLYRG++ +I P A CF G+
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGF 93
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 352 bits (903), Expect = 8e-97
Identities = 170/267 (63%), Positives = 199/267 (74%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C V VG PLDT+KVRLQ P G+PP+Y G +DCF +TL EG G Y+GMAAP+IGV
Sbjct: 23 CLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGV 82
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQG 362
TPMFAVCFFG+ LG+KLQ K L+ PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q
Sbjct: 83 TPMFAVCFFGFGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQA 142
Query: 363 ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 542
+S E KY G D +KLY+E GIR YKGT TL+RD+PA+G YFM+YEWLK + TPEG
Sbjct: 143 SSGEN-KYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEG 201
Query: 543 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEG 722
S LS R L AGG AG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ EG
Sbjct: 202 KSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEG 261
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGYE 803
+ LY+G + V+IRAFPANAACFLG+E
Sbjct: 262 VTSLYKGFNAVMIRAFPANAACFLGFE 288
Score = 66.2 bits (160), Expect = 1e-10
Identities = 38/86 (44%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Frame = +3
Query: 558 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 722
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGY 800
I GLYRG++ +I P A CF G+
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGF 93
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/72 (36%), Positives = 32/72 (44%)
Frame = +3
Query: 15 VGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMF 194
V P D LK R Q P PG+ P G D + + EG YKG A +I P
Sbjct: 226 VAIPPDVLKSRFQTAP---PGKYP--NGFRDVLRELIREEGVTSLYKGFNAVMIRAFPAN 280
Query: 195 AVCFFGYNLGRK 230
A CF G+ + K
Sbjct: 281 AACFLGFEIAMK 292
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 317 bits (813), Expect = 2e-86
Identities = 159/269 (59%), Positives = 197/269 (73%), Gaps = 2/269 (0%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
CTV+VG P DT+KVR+Q MP+PKPGE P + G +DC +T+S EG YKGMAAPL+GV
Sbjct: 17 CTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGMAAPLVGV 76
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQ- 359
+P+FAV F G +G+ LQ D + +T Q AG L+GVFTT +M PGERIKCLLQVQ
Sbjct: 77 SPLFAVFFGGCAVGKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQ 136
Query: 360 -GASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTP 536
G++ Y GP DV++KLYK+GGI SIY+GT ATLLRDIPA+ Y YE+LK+ +
Sbjct: 137 AGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYLSVYEYLKKKFSG 196
Query: 537 EGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMAN 716
EG ++ LSPG TL AGG+AG+ NW VCIP D LKSRLQTAPEGKYP G+R V RE++
Sbjct: 197 EGAQRT-LSPGATLMAGGLAGIANWGVCIPADVLKSRLQTAPEGKYPDGIRGVLREVLRE 255
Query: 717 EGIVGLYRGVSPVLIRAFPANAACFLGYE 803
EG L++G PV++RAFPANAACF G E
Sbjct: 256 EGPRALFKGFWPVMLRAFPANAACFFGLE 284
Score = 44.3 bits (103), Expect = 5e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Frame = +3
Query: 582 AGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYPH--GLRSVFREMMANEGIVGLYRGV 746
AGG+ G C +V P DT+K R+QT P G+ P G + ++ EG LY+G+
Sbjct: 10 AGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGM 69
Query: 747 SPVLIRAFPANAACFLG 797
+ L+ P A F G
Sbjct: 70 AAPLVGVSPLFAVFFGG 86
Score = 38.1 bits (87), Expect = 0.033
Identities = 24/66 (36%), Positives = 30/66 (45%)
Frame = +3
Query: 24 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMFAVC 203
P D LK RLQ P G+ P G+ + L EGP +KG ++ P A C
Sbjct: 225 PADVLKSRLQTAP---EGKYP--DGIRGVLREVLREEGPRALFKGFWPVMLRAFPANAAC 279
Query: 204 FFGYNL 221
FFG L
Sbjct: 280 FFGLEL 285
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 316 bits (809), Expect = 6e-86
Identities = 149/267 (55%), Positives = 194/267 (72%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C V+ G PLDT+KVRLQ MP P PGE P+Y+G DC +T+ NEG G YKGM+APL GV
Sbjct: 28 CNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGV 87
Query: 183 TPMFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQG 362
P+FA+CF GY LG++LQ + E+ LT PQIF AG SG+F+T IM PGERIK LLQ Q
Sbjct: 88 APIFAMCFAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQ 147
Query: 363 ASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEG 542
KY G D KLYKEGG+RS++KG+ AT+LRD+PA G YF+ YE L+++ +
Sbjct: 148 GQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSK- 206
Query: 543 GDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEG 722
+ +S T+FAGG+AGM W++ +P D LKSRLQ+APEG Y HG+RSVF++++ +G
Sbjct: 207 SETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDG 266
Query: 723 IVGLYRGVSPVLIRAFPANAACFLGYE 803
+ LYRGV+P+++RAFPANAACF G E
Sbjct: 267 PLALYRGVTPIMLRAFPANAACFFGIE 293
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Frame = +3
Query: 561 SPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEGI 725
+P ++ GG G+CN L P DT+K RLQT P G+ P G + + NEG+
Sbjct: 14 NPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGV 73
Query: 726 VGLYRGVSPVLIRAFPANAACFLGY 800
GLY+G+S L P A CF GY
Sbjct: 74 RGLYKGMSAPLTGVAPIFAMCFAGY 98
Score = 46.6 bits (109), Expect = 9e-05
Identities = 24/73 (32%), Positives = 35/73 (47%)
Frame = +3
Query: 12 VVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPM 191
++G P D LK RLQ+ P E G+ F + +GP+ Y+G+ ++ P
Sbjct: 230 ILGMPADVLKSRLQSAP-----EGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPA 284
Query: 192 FAVCFFGYNLGRK 230
A CFFG L K
Sbjct: 285 NAACFFGIELANK 297
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 193 bits (491), Expect = 5e-49
Identities = 116/277 (41%), Positives = 147/277 (53%), Gaps = 12/277 (4%)
Frame = +3
Query: 9 VVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTP 188
+VVG P DT+KV+LQ+ P P PG+ P Y G +D QT+++EG G YKGM APL V
Sbjct: 19 LVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAA 78
Query: 189 MFAVCFFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGAS 368
AV F L + PLT Q F AG +G + + P E IKC LQ QGA
Sbjct: 79 FNAVLFTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSFLACPTELIKCRLQAQGAL 138
Query: 369 K---------EPPKYKGPGDVIRK-LYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWL 518
KY GP DV R L EGG R ++KG T R++P T F +YE
Sbjct: 139 AGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAF 198
Query: 519 KEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPH--GLRS 692
K L G D S L G + AGG+AG W + P D +KS LQ + K P G
Sbjct: 199 KRFLA-GGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVLQ-VDDYKNPRYTGSMD 256
Query: 693 VFREMMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 803
FR+++ +EG+ GLY+G P + R+ PANAACFL YE
Sbjct: 257 AFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYE 293
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 2/149 (1%)
Frame = +3
Query: 90 YKGLVDCFLQTLSNEGPV-GFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTP-LT 263
Y G +D L +EG G +KG+ P A F Y ++ +T L
Sbjct: 153 YGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLG 212
Query: 264 KPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSI 443
+ + AG ++G I+ P + +K +LQV P+Y G D RK+ K G++ +
Sbjct: 213 QGSLIMAGGVAGASFWGIVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGL 270
Query: 444 YKGTAATLLRDIPATGTYFMSYEWLKEIL 530
YKG + R +PA F++YE + L
Sbjct: 271 YKGFGPAMARSVPANAACFLAYEMTRSSL 299
Score = 59.7 bits (143), Expect = 1e-08
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 16/193 (8%)
Frame = +3
Query: 279 AAGMLSGVFTTAIMTPGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 452
A+G + G + P + IK LQ Q A + P+Y G D +++ G + +YKG
Sbjct: 9 ASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKG 68
Query: 453 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 632
A L F ++ +L E G +S + AG AG + P +
Sbjct: 69 MGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTE 126
Query: 633 TLKSRLQT-------------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAF 770
+K RLQ KY G V R ++ +EG GL++G+ P R
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREV 185
Query: 771 PANAACFLGYEGF 809
P NA F YE F
Sbjct: 186 PGNATMFAAYEAF 198
Score = 40.0 bits (92), Expect = 0.009
Identities = 23/68 (33%), Positives = 29/68 (42%)
Frame = +3
Query: 24 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTPMFAVC 203
P D +K LQ P Y G +D F + L +EG G YKG + P A C
Sbjct: 233 PTDVVKSVLQVDDYKNPR----YTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAAC 288
Query: 204 FFGYNLGR 227
F Y + R
Sbjct: 289 FLAYEMTR 296
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 161 bits (408), Expect = 2e-39
Identities = 97/273 (35%), Positives = 138/273 (50%), Gaps = 8/273 (2%)
Frame = +3
Query: 9 VVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTP 188
V+ GQP DT+KV++Q P +Y+GL DC L+T S G GFYKG + LI
Sbjct: 24 VLTGQPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIA 76
Query: 189 MFAVCFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ- 353
+V F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ
Sbjct: 77 ENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQT 136
Query: 354 ---VQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKE 524
++ + K V+++++++ G Y G ++TLLR++P +F YE L
Sbjct: 137 MYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSR 195
Query: 525 ILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFRE 704
G K L P + +GG G+C WL P D +KSR+Q GL F
Sbjct: 196 SFFASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLS 255
Query: 705 MMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 803
++ NEGI LY G+ P +IRAFPAN A FL YE
Sbjct: 256 IVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288
Score = 63.9 bits (154), Expect = 6e-10
Identities = 47/175 (26%), Positives = 83/175 (47%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 PLDTLKVRLQAM-PIPKPGEPPVYKGLVDCFLQTL-SNEGPVGFYKGMAAPLIGVTPMFA 197
P + +K RLQ M + G+ + V ++ + +GP+GFY G+++ L+ P +
Sbjct: 126 PTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYF 185
Query: 198 VCFFGYNLGRKL----QVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGA 365
F GY L R + KDE P+ + +G G+ + P + IK +QV
Sbjct: 186 FFFGGYELSRSFFASGRSKDELGPVP---LMLSGGFGGICLWLAVYPVDCIKSRIQVLSM 242
Query: 366 SKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEIL 530
+ K G + K GI ++Y G T++R PA G F++YE+ ++++
Sbjct: 243 TG---KQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/79 (29%), Positives = 33/79 (41%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C + P+D +K R+Q + + GLV FL + NEG Y G+ +I
Sbjct: 222 CLWLAVYPVDCIKSRIQVLSMTGK-----QTGLVRTFLSIVKNEGITALYSGLKPTMIRA 276
Query: 183 TPMFAVCFFGYNLGRKLQV 239
P F Y RKL +
Sbjct: 277 FPANGALFLAYEYSRKLMM 295
Score = 38.9 bits (89), Expect = 0.019
Identities = 25/75 (33%), Positives = 34/75 (45%)
Frame = +3
Query: 576 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 755
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 756 LIRAFPANAACFLGY 800
LI N+ F+ Y
Sbjct: 71 LIANIAENSVLFMCY 85
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 160 bits (404), Expect = 6e-39
Identities = 97/273 (35%), Positives = 136/273 (49%), Gaps = 8/273 (2%)
Frame = +3
Query: 9 VVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGVTP 188
V+ GQP DT+KV++Q P +Y+GL DC L+T S G GFYKG + LI
Sbjct: 24 VLTGQPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIA 76
Query: 189 MFAVCFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ- 353
+V F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ
Sbjct: 77 ENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQT 136
Query: 354 ---VQGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKE 524
++ + K VI+ + ++ G Y G ++TLLR++P +F YE L
Sbjct: 137 MYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSR 195
Query: 525 ILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFRE 704
G K L P + +GG+ G+C WL P D +KSR+Q G F
Sbjct: 196 SFFASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFIN 255
Query: 705 MMANEGIVGLYRGVSPVLIRAFPANAACFLGYE 803
++ NEGI LY G+ P +IRAFPAN A FL YE
Sbjct: 256 VVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288
Score = 65.1 bits (157), Expect = 3e-10
Identities = 49/175 (28%), Positives = 85/175 (48%), Gaps = 6/175 (3%)
Frame = +3
Query: 24 PLDTLKVRLQAM-PIPKPGEPPVYKGLVDCFLQT-LSNEGPVGFYKGMAAPLIGVTPMFA 197
P + +K RLQ M + G+ + V +++ L +GP+GFY G+++ L+ P +
Sbjct: 126 PTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYF 185
Query: 198 VCFFGYNLGRKL----QVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGA 365
F GY L R + KDE P+ + +G + G+ + P + IK +QV
Sbjct: 186 FFFGGYELSRSFFASGRSKDELGPVP---LMLSGGVGGICLWLAVYPVDCIKSRIQVLSM 242
Query: 366 SKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEIL 530
S K G + K GI ++Y G T++R PA G F++YE+ ++++
Sbjct: 243 SG---KQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 38.9 bits (89), Expect = 0.019
Identities = 25/75 (33%), Positives = 34/75 (45%)
Frame = +3
Query: 576 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 755
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 756 LIRAFPANAACFLGY 800
LI N+ F+ Y
Sbjct: 71 LIANIAENSVLFMCY 85
Score = 37.0 bits (84), Expect = 0.073
Identities = 20/79 (25%), Positives = 32/79 (40%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVGFYKGMAAPLIGV 182
C + P+D +K R+Q + + G + F+ + NEG Y G+ +I
Sbjct: 222 CLWLAVYPVDCIKSRIQVLSMSGK-----QAGFIRTFINVVKNEGITALYSGLKPTMIRA 276
Query: 183 TPMFAVCFFGYNLGRKLQV 239
P F Y RKL +
Sbjct: 277 FPANGALFLAYEYSRKLMM 295
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 158 bits (399), Expect = 2e-38
Identities = 105/280 (37%), Positives = 144/280 (51%), Gaps = 13/280 (4%)
Frame = +3
Query: 3 CTVVVGQPLDTLKVRLQAMPIPKPGEP--PVYKGLVDCFLQTLSNEGPVGFYKGMAAPLI 176
C V G P D +KVR Q + K TL GFYKG+ PL+
Sbjct: 48 CAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVKGFYKGVIPPLL 107
Query: 177 GVTPMFAVCFFGYNLGRKL----QVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKC 344
GVTP+FAV F+GY++G+KL + + LT Q+ AAG +S + TT + P ER+K
Sbjct: 108 GVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPTTLVTAPTERVKV 167
Query: 345 LLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLK 521
+LQ KG + + KEGGI S++KG+ ATL RD P + YF SYE K
Sbjct: 168 VLQTSS--------KGSFIQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISK 219
Query: 522 EILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGL 686
L + G ++ AGGIAGM WL P DT+K++LQ + + +
Sbjct: 220 NYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQ---NM 276
Query: 687 RSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLGYE 803
S +E+ + GI G + G+ P L+R+FPANAA FLG E
Sbjct: 277 LSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVE 316
Score = 42.7 bits (99), Expect = 0.001
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Frame = +3
Query: 570 RTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFRE-------MMANEGIV 728
++ AGG+ G+C P D +K R Q H + ++ +E + +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 729 GLYRGVSPVLIRAFPANAACFLGYE 803
G Y+GV P L+ P A F GY+
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYD 121
Score = 40.0 bits (92), Expect = 0.009
Identities = 43/188 (22%), Positives = 71/188 (37%), Gaps = 9/188 (4%)
Frame = +3
Query: 6 TVVVGQPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLSNEGPVG-FYKGMAAPLIGV 182
T +V P + +KV LQ KG +T+ EG + +KG A L
Sbjct: 155 TTLVTAPTERVKVVLQTSS----------KGSFIQAAKTIVKEGGIASLFKGSLATLARD 204
Query: 183 TPMFAVCFFGYNLGRKL-------QVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIK 341
P A+ F Y + + Q ++ P+ + AG ++G+ + P + IK
Sbjct: 205 GPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIK 264
Query: 342 CLLQVQGASKEPPKYKGPGDVIRKLY-KEGGIRSIYKGTAATLLRDIPATGTYFMSYEWL 518
LQ + +++Y + GGI+ + G LLR PA F+ E
Sbjct: 265 TKLQASSTRQNMLS------ATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEMT 318
Query: 519 KEILTPEG 542
+ G
Sbjct: 319 HSLFKKYG 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 108,451,973
Number of Sequences: 369166
Number of extensions: 2491076
Number of successful extensions: 7214
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6005
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6564
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)