Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_001_F06 (633 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo 44 3e-04 sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 (STE... 40 0.006 sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 (STE... 39 0.008 sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 (STE... 37 0.032 sp|Q92CH6|MUTS2_LISIN MutS2 protein 32 1.4 sp|Q8K9J9|RNE_BUCAP Ribonuclease E (RNase E) 30 3.9 sp|P52519|P100_HHV7J Large structural phosphoprotein homolo... 30 3.9 sp|Q9UTK5|ALM1_SCHPO Abnormal long morphology protein 1 (Sp8) 30 6.7 sp|P47459|P65H_MYCGE Proline-rich P65 protein homolog 30 6.7 sp|Q95ZG4|SPC98_DICDI Spindle pole body component 98 (Spc98... 30 6.7
>sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo Length = 669 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/69 (33%), Positives = 39/69 (56%) Frame = +3 Query: 330 LNPNSFVNVEEIYRNLETKSYSELQQLLNRIDSDLQSELNNLEIRYLHKRQPILDAINEK 509 ++ S VE + L+ ++ +L Q L ID +++ E+ L +Y KRQPI+DA+N K Sbjct: 596 MHTQSHAYVEGEFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAK 655 Query: 510 GKPIARVNS 536 K +N+ Sbjct: 656 RKRQQNINN 664
>sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1) Length = 491 Score = 39.7 bits (91), Expect = 0.006 Identities = 20/45 (44%), Positives = 27/45 (60%) Frame = +3 Query: 375 LETKSYSELQQLLNRIDSDLQSELNNLEIRYLHKRQPILDAINEK 509 L+ S ELQ L +D ++ E+ L RY KRQPILDA++ K Sbjct: 440 LKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAK 484
>sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) Length = 497 Score = 39.3 bits (90), Expect = 0.008 Identities = 20/45 (44%), Positives = 27/45 (60%) Frame = +3 Query: 375 LETKSYSELQQLLNRIDSDLQSELNNLEIRYLHKRQPILDAINEK 509 L+ S ELQ L +D ++ E+ L RY KRQPILDA++ K Sbjct: 446 LKNLSLEELQMRLKALDPMMEREIEELHQRYSAKRQPILDAMDAK 490
>sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2) Length = 487 Score = 37.4 bits (85), Expect = 0.032 Identities = 18/48 (37%), Positives = 29/48 (60%) Frame = +3 Query: 366 YRNLETKSYSELQQLLNRIDSDLQSELNNLEIRYLHKRQPILDAINEK 509 Y L++ + +LQ+ L +D ++ E+ + +Y KRQPILDAI K Sbjct: 433 YEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAK 480
>sp|Q92CH6|MUTS2_LISIN MutS2 protein Length = 785 Score = 32.0 bits (71), Expect = 1.4 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Frame = +3 Query: 339 NSFVNVEEIYRNLETKSYSELQQLLNRIDS---DLQSELNNLEIRYLHKRQPILDAINEK 509 N ++ E RNL + Y E ++L D+ DLQ E+ N Y ++ +L+ NEK Sbjct: 520 NDMISSLEEKRNLAEREYEEARELARGADALLKDLQKEITN----YYQQKDKLLEQANEK 575 Query: 510 GKPI 521 I Sbjct: 576 AAGI 579
>sp|Q8K9J9|RNE_BUCAP Ribonuclease E (RNase E) Length = 968 Score = 30.4 bits (67), Expect = 3.9 Identities = 21/88 (23%), Positives = 46/88 (52%), Gaps = 5/88 (5%) Frame = +3 Query: 174 KTHLNSIFSNLFHNLDFYNAFL*CFQNNFYQKYFSLISIFLQEPAAQSPCGAL--NPNSF 347 K + NSI + LF+N + + F+ +N+F +K+ + + + Q+ L F Sbjct: 553 KNYNNSIINALFNNKNLFFKFIVWIKNSFLKKHIFVKNESFKRNIFQNKKNILFAKKEEF 612 Query: 348 VNVEEIYR---NLETKSYSELQQLLNRI 422 ++EEI++ + + ++ +QLLN++ Sbjct: 613 NSIEEIHKKDNQVSSIDNNKKKQLLNKV 640
>sp|P52519|P100_HHV7J Large structural phosphoprotein homolog (PP100) Length = 755 Score = 30.4 bits (67), Expect = 3.9 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 13/97 (13%) Frame = +3 Query: 243 CFQNNFYQKYFSLISIFLQE-PAAQSPCGALNPNSFVNVEEIYRNL------------ET 383 CF + F++ SL + ++E P S C NS NV+ +Y NL + Sbjct: 17 CFLSRFFENISSLPVVDIRENPWILSQCIVKTGNSINNVKTLYNNLILWIYFHQTLCKKK 76 Query: 384 KSYSELQQLLNRIDSDLQSELNNLEIRYLHKRQPILD 494 Y E+ Q + ++ L+ YL +RQ I D Sbjct: 77 PDYEEVWQEILKVQKILKD--------YLEQRQMITD 105
>sp|Q9UTK5|ALM1_SCHPO Abnormal long morphology protein 1 (Sp8) Length = 1727 Score = 29.6 bits (65), Expect = 6.7 Identities = 17/46 (36%), Positives = 24/46 (52%) Frame = +3 Query: 330 LNPNSFVNVEEIYRNLETKSYSELQQLLNRIDSDLQSELNNLEIRY 467 L F +E + + SYSE + LL SDLQS+ +LE +Y Sbjct: 890 LEKQRFSTLEAKFTQQKNTSYSEREALLESSLSDLQSKHTSLESQY 935
>sp|P47459|P65H_MYCGE Proline-rich P65 protein homolog Length = 372 Score = 29.6 bits (65), Expect = 6.7 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Frame = +3 Query: 351 NVEEIYRNLETKSYSELQQLLNRIDSD-LQSELNNLEIRYLHKRQPILDAINEKGK 515 N+E I NLE K ++ +QL D+ L ++N LEIR + K ++++E K Sbjct: 243 NLEAIRHNLEQKIQNQSKQLRTNFDTQKLDDKINELEIR-MQKLTRNFESLSELSK 297
>sp|Q95ZG4|SPC98_DICDI Spindle pole body component 98 (Spc98) (DdSpc98) Length = 812 Score = 29.6 bits (65), Expect = 6.7 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = -2 Query: 149 KAFNNFINHIRKLTRIYIQNNYSISSE*IKQKV 51 K FN+F NH+ L + Y + Y SE +K KV Sbjct: 755 KEFNSFRNHLNNLYQEYTTSFYKFQSEILKVKV 787
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,258,280 Number of Sequences: 369166 Number of extensions: 1234038 Number of successful extensions: 3444 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3345 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3442 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5072399280 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)