Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_E21
(537 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RAL... 215 5e-56
sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RAL... 214 1e-55
sp|P51977|AL1A1_SHEEP Retinal dehydrogenase 1 (RalDH1) (RAL... 212 5e-55
sp|P48644|AL1A1_BOVIN Retinal dehydrogenase 1 (RalDH1) (RAL... 212 5e-55
sp|Q8HYE4|AL1A1_MACFA Retinal dehydrogenase 1 (RalDH1) (RAL... 210 2e-54
sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 (RalDH1) (RAL... 210 2e-54
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH... 209 3e-54
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RAL... 209 3e-54
sp|Q29491|ALDH2_MACPR Aldehyde dehydrogenase, cytosolic 2 (... 209 5e-54
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial... 208 6e-54
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 509
Score = 215 bits (548), Expect = 5e-56
Identities = 107/155 (69%), Positives = 120/155 (77%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQF KILDLIESGK EGAKL GG GN GYFIQPTVF +V D+MRIAKEEIFGPVQ
Sbjct: 355 DKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQ 414
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF T++EVI+RANN+ YGL A VFT DI+KA+ AL+AG+VWVNCY PF
Sbjct: 415 QIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPF 474
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YGL+ Y EVK VTI IPQ+NS
Sbjct: 475 GGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS 509
>sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 496
Score = 214 bits (545), Expect = 1e-55
Identities = 103/155 (66%), Positives = 123/155 (79%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ+NKILDLIESGK EGAKL GG GN GYFIQPTVF +V D MRIAKEEIFGPVQ
Sbjct: 342 DKEQYNKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEEIFGPVQ 401
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF ++++VI+RANN+ YGL AG+FT D++KA+ ++ AL+AG+VWVNCY V PF
Sbjct: 402 QIMKFKSLDDVIKRANNTTYGLSAGIFTKDLDKAVTVSSALQAGTVWVNCYSVVSAQVPF 461
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YGL+ Y EVK VT+ I Q+NS
Sbjct: 462 GGFKMSGNGRELGEYGLQQYTEVKTVTVKISQKNS 496
>sp|P51977|AL1A1_SHEEP Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 501
Score = 212 bits (539), Expect = 5e-55
Identities = 104/155 (67%), Positives = 122/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ+ KILDLIESGK EGAKL GG GN GYFIQPTVF DV D+MRIAKEEIFGPVQ
Sbjct: 347 DKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQ 406
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF ++++VI+RANN+ YGL AG+FT+DI+KAI ++ AL++G+VWVNCY V PF
Sbjct: 407 QIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPF 466
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YG Y EVK VTI I Q+NS
Sbjct: 467 GGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS 501
>sp|P48644|AL1A1_BOVIN Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 501
Score = 212 bits (539), Expect = 5e-55
Identities = 104/155 (67%), Positives = 122/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ+ KILDLIESGK EGAKL GG GN GYFIQPTVF DV D+MRIAKEEIFGPVQ
Sbjct: 347 DKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQ 406
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF ++++VI+RANN+ YGL AG+FT+DI+KAI ++ AL++G+VWVNCY V PF
Sbjct: 407 QIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPF 466
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YG Y EVK VTI I Q+NS
Sbjct: 467 GGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS 501
>sp|Q8HYE4|AL1A1_MACFA Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 501
Score = 210 bits (535), Expect = 2e-54
Identities = 102/155 (65%), Positives = 122/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ++KILDLIESGK EGAKL GG GN GYF+QPTVF +V D MRIAKEEIFGPVQ
Sbjct: 347 DKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQ 406
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF ++++VI+RANN+ YGL AGVFT+DI+KA+ ++ AL+AG+VWVNCY V PF
Sbjct: 407 QIMKFKSLDDVIKRANNTFYGLSAGVFTNDIDKAVTISSALQAGTVWVNCYGVVTAQCPF 466
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YG Y EVK VT+ I Q+NS
Sbjct: 467 GGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS 501
>sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 501
Score = 210 bits (534), Expect = 2e-54
Identities = 103/155 (66%), Positives = 121/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ++KILDLIESGK EGAKL GG GN GYF+QPTVF +V D MRIAKEEIFGPVQ
Sbjct: 347 DKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQ 406
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF ++++VI+RANN+ YGL AGVFT DI+KAI ++ AL+AG+VWVNCY V PF
Sbjct: 407 QIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPF 466
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YG Y EVK VT+ I Q+NS
Sbjct: 467 GGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS 501
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 209 bits (533), Expect = 3e-54
Identities = 99/155 (63%), Positives = 126/155 (81%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DK+Q+NKIL+LI+SG EGAKL GG +G G+FI+PTVF +V D+MRIAKEEIFGPVQ
Sbjct: 345 DKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQ 404
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ +F TM+EVIERANNSD+GL A VFT+DINKA+M++ A++AG+VW+NCY+ +PF
Sbjct: 405 EILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPF 464
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRE+G +GL Y EVK VT+ IPQ+NS
Sbjct: 465 GGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 209 bits (532), Expect = 3e-54
Identities = 98/155 (63%), Positives = 126/155 (81%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DK+Q+NK+L+LI+SG EGAKL GG +G G+FI+PTVF +V D+MRIAKEEIFGPVQ
Sbjct: 345 DKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQ 404
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ +F TM+EVIERANNSD+GL A VFT+DINKA+M++ A++AG+VW+NCY+ +PF
Sbjct: 405 EILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPF 464
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRE+G +GL Y EVK VT+ IPQ+NS
Sbjct: 465 GGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|Q29491|ALDH2_MACPR Aldehyde dehydrogenase, cytosolic 2 (ALDH class 1) (Non-lens ALDH1)
(ALDH1-NL)
Length = 240
Score = 209 bits (531), Expect = 5e-54
Identities = 102/155 (65%), Positives = 122/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
DKEQ++KI+DLIESGK EGAKL GG GN GYFIQPTVF +V D MRIAKEEIFGPVQ
Sbjct: 86 DKEQYDKIIDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEEIFGPVQ 145
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF +++EVI+RANN+ YGL AGVFT D++KA+ ++ AL+AG+VWVNCY V PF
Sbjct: 146 QIMKFKSLDEVIKRANNTFYGLAAGVFTKDLDKAVTVSAALQAGTVWVNCYMANSVQCPF 205
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GGFK SG GRELG YGL Y EVK VT+ I ++NS
Sbjct: 206 GGFKMSGNGRELGEYGLHEYTEVKTVTMKISKKNS 240
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDHI)
(ALDH-E2)
Length = 500
Score = 208 bits (530), Expect = 6e-54
Identities = 100/155 (64%), Positives = 121/155 (78%)
Frame = +1
Query: 1 DKEQFNKILDLIESGKHEGAKLVTGGNRIGNVGYFIQPTVFGDVKDNMRIAKEEIFGPVQ 180
D+ QFNK+L I+SGK EGAKL+ GG + GYFIQPTVFGDV+D M IAKEEIFGPV
Sbjct: 346 DETQFNKVLGYIKSGKEEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVM 405
Query: 181 SVFKFNTMEEVIERANNSDYGLGAGVFTSDINKAIMMTQALEAGSVWVNCYDVGLVTAPF 360
+ KF T+EEV+ RANNS YGL A VFT D++KA ++QAL+AG+VW+NCYDV +PF
Sbjct: 406 QILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPF 465
Query: 361 GGFKQSGVGRELGCYGLEPYIEVKGVTIAIPQRNS 465
GG+K SG GRELG YGL+ Y EVK VTI +PQ+NS
Sbjct: 466 GGYKMSGNGRELGEYGLQAYTEVKTVTIKVPQKNS 500
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,977,019
Number of Sequences: 369166
Number of extensions: 1145568
Number of successful extensions: 2859
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2743
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3699545625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)