Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_E18
(893 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5Y171|Spre2_XENTR Sprouty-related, EVH1 domain containi... 46 1e-04
sp|Q924S7|Spre2_MOUSE Sprouty-related, EVH1 domain containi... 46 2e-04
sp|Q7Z698|Spre2_HUMAN Sprouty-related, EVH1 domain containi... 46 2e-04
sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containi... 46 2e-04
sp|Q7Z699|Spre1_HUMAN Sprouty-related, EVH1 domain containi... 45 2e-04
sp|Q66JG9|Spre1_XENTR Sprouty-related, EVH1 domain containi... 45 2e-04
sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containi... 45 3e-04
sp|Q6P6N5|SPD3_MOUSE Sprouty-related, EVH1 domain containin... 44 6e-04
sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein ... 33 0.82
sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein ... 32 3.1
>sp|Q5Y171|Spre2_XENTR Sprouty-related, EVH1 domain containing protein 2 (Spred-2)
Length = 409
Score = 46.2 bits (108), Expect = 1e-04
Identities = 22/61 (36%), Positives = 33/61 (54%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLEKE 180
D+ + LEC L D Y++ PTFH W N + GLTF + A F+R + ++ L +
Sbjct: 65 DKLVLLECYLKKDLVYWKATPTFHHWLVDNRRFGLTFQSPADARAFDRGVRKAIEDLTEG 124
Query: 181 S 183
S
Sbjct: 125 S 125
Score = 33.1 bits (74), Expect = 1.1
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Frame = +1
Query: 712 SNEGASGDNMMSWI--PPKRARNSHRPGILI-CVYCRRRFRPQSNPPGSCELAPDRARQL 882
+N G S D S I P R + + G C+YCR F N G C+ APD R
Sbjct: 268 TNFGISKDLKTSVINTQPSRCSSRRKDGERSRCIYCRDMFNHDENRRGQCQDAPDSVRNC 327
Query: 883 V 885
+
Sbjct: 328 I 328
>sp|Q924S7|Spre2_MOUSE Sprouty-related, EVH1 domain containing protein 2 (Spred-2)
Length = 410
Score = 45.8 bits (107), Expect = 2e-04
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRL 171
D+ + LEC + D Y + NPTFH W N K GLTF + A F+R + ++ L
Sbjct: 66 DKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 122
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYCR F + N G C+ APD R +
Sbjct: 301 CVYCRDMFNHEENRRGHCQDAPDAVRTCI 329
>sp|Q7Z698|Spre2_HUMAN Sprouty-related, EVH1 domain containing protein 2 (Spred-2)
Length = 418
Score = 45.8 bits (107), Expect = 2e-04
Identities = 22/57 (38%), Positives = 31/57 (54%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRL 171
D+ + LEC + D Y + NPTFH W N K GLTF + A F+R + ++ L
Sbjct: 66 DKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL 122
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYCR F + N G C+ APD R +
Sbjct: 309 CVYCRDMFNHEENRRGHCQDAPDSVRTCI 337
>sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containing protein 2 (Spred-2)
Length = 413
Score = 45.8 bits (107), Expect = 2e-04
Identities = 23/61 (37%), Positives = 32/61 (52%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLEKE 180
D+ + LEC + D Y + PTFH W N K GLTF + A F+R + L+ L +
Sbjct: 66 DKQVILECFVRKDLIYTKATPTFHHWKVDNKKCGLTFQSPADARAFDRGVRKALEDLTEG 125
Query: 181 S 183
S
Sbjct: 126 S 126
Score = 31.6 bits (70), Expect = 3.1
Identities = 13/29 (44%), Positives = 15/29 (51%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYCR F + N G C APD R +
Sbjct: 304 CVYCRDMFNHEENRRGQCHDAPDPIRTCI 332
>sp|Q7Z699|Spre1_HUMAN Sprouty-related, EVH1 domain containing protein 1 (Spred-1)
Length = 444
Score = 45.4 bits (106), Expect = 2e-04
Identities = 20/59 (33%), Positives = 32/59 (54%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLEK 177
D+ + LEC L D Y ++ PTFH W + K GLTF + A F+R + ++ + +
Sbjct: 67 DKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISQ 125
Score = 33.5 bits (75), Expect = 0.82
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYC+ RF + N G C+ APD ++ +
Sbjct: 335 CVYCQERFNHEENVRGKCQDAPDPIKRCI 363
>sp|Q66JG9|Spre1_XENTR Sprouty-related, EVH1 domain containing protein 1 (Spred-1)
Length = 406
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/59 (35%), Positives = 32/59 (54%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLEK 177
D+ + LEC L D Y ++ PTFH W + K GLTF + A F+R + ++ L +
Sbjct: 64 DKTVVLECVLRRDLVYNKVTPTFHHWRIGDKKFGLTFQSPADARAFDRGIRRAIEDLSQ 122
Score = 33.1 bits (74), Expect = 1.1
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYC+ RF + N G C+ APD ++ +
Sbjct: 297 CVYCQERFNHEENGRGKCQDAPDPIQRCI 325
>sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containing protein 1 (Spred-1)
Length = 444
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/48 (41%), Positives = 27/48 (56%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFER 144
D+ + LEC L D Y ++ PTFH W + K GLTF + A F+R
Sbjct: 67 DKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDR 114
Score = 34.3 bits (77), Expect = 0.48
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +1
Query: 799 CVYCRRRFRPQSNPPGSCELAPDRARQLV 885
CVYC+ RF + N G C+ APD ++ +
Sbjct: 335 CVYCQERFNHEENARGKCQDAPDPVKRCI 363
>sp|Q6P6N5|SPD3_MOUSE Sprouty-related, EVH1 domain containing protein 3 (Spred-3)
Length = 408
Score = 43.9 bits (102), Expect = 6e-04
Identities = 21/61 (34%), Positives = 32/61 (52%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLEKE 180
D+ +LEC L Y ++NP FH W+ + K GLTF + A+ F++ L L +
Sbjct: 57 DQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALSRG 116
Query: 181 S 183
S
Sbjct: 117 S 117
>sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein (VASP)
Length = 384
Score = 33.5 bits (75), Expect = 0.82
Identities = 17/58 (29%), Positives = 24/58 (41%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLE 174
D+ + + C + Y + PTFH W GL F + E A F L+ LE
Sbjct: 57 DQQVVINCAIVRGIKYNQATPTFHQWRDARQVWGLNFGSKEDATQFAAAMASALEALE 114
>sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein (VASP)
Length = 380
Score = 31.6 bits (70), Expect = 3.1
Identities = 16/58 (27%), Positives = 23/58 (39%)
Frame = +1
Query: 1 DRNLSLECKLDSDTSYYRINPTFHCWTTKNDKIGLTFDTYEAAENFERFFNQILKRLE 174
D+ + + C + Y + P FH W GL F + E A F L+ LE
Sbjct: 57 DQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE 114
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,884,824
Number of Sequences: 369166
Number of extensions: 1874109
Number of successful extensions: 4569
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4439
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4568
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)