Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_D22
(893 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5DRB5|PCDG5_PANTR Protocadherin gamma A5 precursor (PCD... 70 6e-12
sp|Q9Y5G8|PCDG5_HUMAN Protocadherin gamma A5 precursor (PCD... 70 1e-11
sp|Q5DRA9|PCDGE_PANTR Protocadherin gamma B2 precursor (PCD... 66 1e-10
sp|Q08174|PCDH1_HUMAN Protocadherin 1 precursor (Protocadhe... 66 1e-10
sp|Q14517|FATH_HUMAN Cadherin-related tumor suppressor homo... 65 2e-10
sp|Q9Y5G2|PCDGE_HUMAN Protocadherin gamma B2 precursor (PCD... 64 7e-10
sp|Q9NYQ6|CELR1_HUMAN Cadherin EGF LAG seven-pass G-type re... 63 1e-09
sp|Q9HCU4|CELR2_HUMAN Cadherin EGF LAG seven-pass G-type re... 62 2e-09
sp|O35161|CELR1_MOUSE Cadherin EGF LAG seven-pass G-type re... 62 2e-09
sp|Q91ZI0|CELR3_MOUSE Cadherin EGF LAG seven-pass G-type re... 62 3e-09
>sp|Q5DRB5|PCDG5_PANTR Protocadherin gamma A5 precursor (PCDH-gamma-A5)
Length = 931
Score = 70.5 bits (171), Expect = 6e-12
Identities = 65/265 (24%), Positives = 112/265 (42%), Gaps = 15/265 (5%)
Frame = +3
Query: 114 EGMCCEMRECVVEAKVVARDKSSDQSIYVXXXXXXXXXXXXWPRFFEPYKVTLVPENISI 293
E +C + CVV ++ +K + V +PRF + V EN +
Sbjct: 93 EELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDN----FPRFRDEELKVKVNENAAA 148
Query: 294 GSFICLEPAYDADVDPNN----QITEYFFEEPTGIFKLDQKKFPSIRLIVQKHLDYNVKS 461
G+ + L A DADV N+ Q++ + D +K+P L++++ LD ++
Sbjct: 149 GTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVIGTDGQKYPE--LVLEQPLDREKET 206
Query: 462 VFSASLEACS------TQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQA 608
V L A + T I V V D +F Y + + EN V +L + A
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTA 266
Query: 609 VYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMD 788
+ + K+ Y F + I +TF++ N G I + L ++ +F + V D
Sbjct: 267 TDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL---DYEESRFYLMEVVAQD 323
Query: 789 PMLPKAVANVSITVKDINDNSSVIV 863
A A V +TV+D+NDN+ ++
Sbjct: 324 GGALVASAKVVVTVQDVNDNAPEVI 348
>sp|Q9Y5G8|PCDG5_HUMAN Protocadherin gamma A5 precursor (PCDH-gamma-A5)
Length = 931
Score = 69.7 bits (169), Expect = 1e-11
Identities = 65/265 (24%), Positives = 112/265 (42%), Gaps = 15/265 (5%)
Frame = +3
Query: 114 EGMCCEMRECVVEAKVVARDKSSDQSIYVXXXXXXXXXXXXWPRFFEPYKVTLVPENISI 293
E +C + CVV ++ +K + V +PRF + V EN +
Sbjct: 93 EELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDN----FPRFRDEELKVKVNENAAA 148
Query: 294 GSFICLEPAYDADVDPNN----QITEYFFEEPTGIFKLDQKKFPSIRLIVQKHLDYNVKS 461
G+ + L A DADV N+ Q++ + D +K+P L++++ LD ++
Sbjct: 149 GTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPE--LVLEQPLDREKET 206
Query: 462 VFSASLEACS------TQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQVQA 608
V L A + T I V V D +F Y + + EN V +L + A
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTA 266
Query: 609 VYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMD 788
+ + K+ Y F + I +TF++ N G I + L ++ +F + V D
Sbjct: 267 TDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL---DYEESRFYLMEVVAQD 323
Query: 789 PMLPKAVANVSITVKDINDNSSVIV 863
A A V +TV+D+NDN+ ++
Sbjct: 324 GGALVASAKVVVTVQDVNDNAPEVI 348
>sp|Q5DRA9|PCDGE_PANTR Protocadherin gamma B2 precursor (PCDH-gamma-B2)
Length = 931
Score = 65.9 bits (159), Expect = 1e-10
Identities = 65/223 (29%), Positives = 102/223 (45%), Gaps = 17/223 (7%)
Frame = +3
Query: 249 FEPYKVTL-VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSIR- 422
F+ K+ L + E+ G+ L+PA D+DV PN+ + Y + F L +K+ P R
Sbjct: 133 FKQTKINLKIGESTKPGTTFPLDPALDSDVGPNS-LQRYHLND-NEYFDLAEKQTPDGRK 190
Query: 423 ---LIVQKHLDYNVKSVFSASLEACS------TQTLEIHVQVTDL-----VFLQKHYQME 560
LI+Q LD S+ L A + T +I V+VTD VF Q Y++
Sbjct: 191 YPELILQHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRVKVTDANDNPPVFSQDVYRVT 250
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAK 740
+ E+ +LQV A ++ + +I Y FH D ++ F ++ TG I K L +
Sbjct: 251 LREDVPPGFFVLQVTATDRDEGVNAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFE 310
Query: 741 FRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS-SVIVT 866
Y + A DP A ++ + + D ND + VIVT
Sbjct: 311 IASSYTLSIEA---KDPGDLAAHCSIQVEILDDNDCAPEVIVT 350
>sp|Q08174|PCDH1_HUMAN Protocadherin 1 precursor (Protocadherin 42) (PC42) (Cadherin-like
protein 1)
Length = 1026
Score = 65.9 bits (159), Expect = 1e-10
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 11/218 (5%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F P +PEN +IGS + A D D PN + Y + + + ++K P
Sbjct: 144 PNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNG-VASYELQ----VAEDQEEKQP-- 196
Query: 420 RLIVQKHLD--------YNVKSVFSASLEACSTQTLEIHVQVTD---LVFLQKHYQMEIL 566
+LIV +LD +K S ++ L + V T+ F + Y+ E+
Sbjct: 197 QLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFERPSYEAELS 256
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
EN + ++QV+A + + +I Y FH ++R R+ RNTG I ++ + +
Sbjct: 257 ENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDL 316
Query: 747 QKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSVI 860
+F V A A A V +TVKD+NDN+ I
Sbjct: 317 STLRFSVLAKD-RGTNPKSARAQVVVTVKDMNDNAPTI 353
Score = 33.9 bits (76), Expect = 0.63
Identities = 54/222 (24%), Positives = 86/222 (38%), Gaps = 15/222 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPT--GIFKLDQKKFP 413
P F + PEN G I A DAD N ++ EP G+F + +
Sbjct: 470 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE--- 526
Query: 414 SIRLIVQKHLD------YNVKSVF----SASLEACSTQTLEI-HVQVTDLVFLQKHYQME 560
+ + V+ LD Y +K V S SL+ +T + + D F+ Y
Sbjct: 527 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 586
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAK 740
++EN + V + + ++ ++ DN F I TG+I +
Sbjct: 587 VMENMPALSPVGMVTVIDGDKGENAQVQLSVE-QDN---GDFVIQNGTGTILSSLSFDRE 642
Query: 741 FRQKYKFRVYAVYLMDPMLP--KAVANVSITVKDINDNSSVI 860
+ Y F++ AV D +P A V+I V D NDN+ I
Sbjct: 643 QQSTYTFQLKAV---DGGVPPRSAYVGVTINVLDENDNAPYI 681
>sp|Q14517|FATH_HUMAN Cadherin-related tumor suppressor homolog precursor (Fat protein
homolog)
Length = 4590
Score = 65.5 bits (158), Expect = 2e-10
Identities = 60/214 (28%), Positives = 99/214 (46%), Gaps = 12/214 (5%)
Frame = +3
Query: 252 EPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSIRLIV 431
+PY +T+ EN G+ + A DAD N +I + G F +++ S + +
Sbjct: 3130 DPYAITVF-ENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINEL---SGIIQL 3185
Query: 432 QKHLDYNVKSVFSASLEACS-------TQTLEIHVQVTDL-----VFLQKHYQMEILENF 575
+K LD +++V++ SL+A T T + V V D+ VF + Y + E+
Sbjct: 3186 EKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDI 3245
Query: 576 TVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKY 755
V E+LQV A ++ + + +I Y G+ F I TG++ + L + +Y
Sbjct: 3246 LVGTEVLQVYAASRDIEANAEITYSIISGNE--HGKFSIDSKTGAVFIIENLDYESSHEY 3303
Query: 756 KFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
V A P L VA V++ V DINDN+ V
Sbjct: 3304 YLTVEATDGGTPSL-SDVATVNVNVTDINDNTPV 3336
Score = 56.6 bits (135), Expect = 9e-08
Identities = 53/217 (24%), Positives = 102/217 (47%), Gaps = 14/217 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTG-IFKLDQKKFPS 416
P+F EP+ V E++ +G+ I L A + + + E F +D++ S
Sbjct: 2703 PKFSEPFYTFTVSEDVPVGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQ---S 2759
Query: 417 IRLIVQKHLDYNVKSVFSASLEACSTQ-------TLEIHVQVTDL-----VFLQKHYQME 560
RL ++K LD+ + S+ A TQ ++++ +QV D VF Y+
Sbjct: 2760 GRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAF 2819
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNI-IRDTFRISRNTGSIKLKRKLLA 737
I+EN ++Q++A +S + ++ Y ++ + ++F I+ TG I ++L
Sbjct: 2820 IVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDH 2879
Query: 738 KFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 848
+ R Y+ +V A + + + A V +TV D+ND+
Sbjct: 2880 EKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDS 2916
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 15/219 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F P V E++ G+ I A+D D+ + Q+ + G F +D K ++
Sbjct: 925 PTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVD-KLSGAV 983
Query: 420 RLIVQKHLDYNVKSVFSASLEA-------CSTQTLEIHVQVTDL-------VFLQKHYQM 557
R++ Q LD+ K V++ ++ A + T + V+V D+ VF +
Sbjct: 984 RIVQQ--LDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKG 1041
Query: 558 EILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLA 737
+ E+ V ++ V A +++ + +I Y G + F+I TG I+ +L
Sbjct: 1042 TVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGV--GVFKIGEETGVIETSDRLDR 1099
Query: 738 KFRQKYKFRVYAVYLMDPMLP-KAVANVSITVKDINDNS 851
+ Y V+A ++P + + I V+D+NDN+
Sbjct: 1100 ESTSHYWLTVFAT--DQGVVPLSSFIEIYIEVEDVNDNA 1136
Score = 45.1 bits (105), Expect = 3e-04
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 13/208 (6%)
Frame = +3
Query: 273 VPENISIGSFICLEPAYDADVDPNNQITEYFFE-EPTGIFKLDQKKFPSIRLIVQKHLDY 449
V E+I +G+ + A D++ N +IT G F +D K + + + ++LDY
Sbjct: 3241 VSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSK---TGAVFIIENLDY 3297
Query: 450 NVKSVFSASLEACSTQT------LEIHVQVTDL-----VFLQKHYQMEILENFTVDCEIL 596
+ ++EA T ++V VTD+ VF Q Y I E+ ++ ++
Sbjct: 3298 ESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVI 3357
Query: 597 QVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAV 776
V A + ++ I Y G+ +F I G +K+ + L + Y V A
Sbjct: 3358 TVMADDADGPSNSHIHYSIIDGNQ--GSSFTIDPVRGEVKVTKLLDRETISGYTLTVQAS 3415
Query: 777 YLMDPMLPKA-VANVSITVKDINDNSSV 857
P P+ V+I V D+NDN+ V
Sbjct: 3416 DNGSP--PRVNTTTVNIDVSDVNDNAPV 3441
Score = 43.1 bits (100), Expect = 0.001
Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 9/204 (4%)
Frame = +3
Query: 273 VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSIRLIVQKHLDYN 452
+PE++ G I A DAD+ N +IT FKL+ + L LD
Sbjct: 3034 IPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNP---DTGELKTSTPLDRE 3090
Query: 453 VKSVFSASLEA-------CSTQTLEIHVQVTDLV--FLQKHYQMEILENFTVDCEILQVQ 605
++V+ + A C + V D F Y + + EN + +VQ
Sbjct: 3091 EQAVYHLLVRATDGGGRFCQASIVVTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQ 3150
Query: 606 AVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLM 785
A ++ + KI Y + F I+ +G I+L++ L + + Y + AV
Sbjct: 3151 ATDADAGLNRKILYSL---IDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQG 3207
Query: 786 DPMLPKAVANVSITVKDINDNSSV 857
P A V ++V DINDN V
Sbjct: 3208 LPRRLTATGTVIVSVLDINDNPPV 3231
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 10/146 (6%)
Frame = +3
Query: 441 LDYNVKSVFSASLEACSTQT-----LEIHVQVTDL-----VFLQKHYQMEILENFTVDCE 590
LD+ + S+ A + T + + + V D+ VF Q+ Y + + E +
Sbjct: 2245 LDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTS 2304
Query: 591 ILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVY 770
++QV+A +S+ + I+Y + D F + +TG I L R L + +++ V
Sbjct: 2305 VVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVR 2364
Query: 771 AVYLMDPMLPKAVANVSITVKDINDN 848
AV P L V V++ V D+N N
Sbjct: 2365 AVDGGMPTLSSDVI-VTVDVTDLNGN 2389
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/220 (21%), Positives = 94/220 (42%), Gaps = 17/220 (7%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F + V E+ + S I A D D+ PN +T Y T F +D S+
Sbjct: 820 PEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVT-YSILTDTDTFSID-----SV 873
Query: 420 RLIVQ--KHLDYNVKSVFSASLEACST--------QTLEIHVQVTDL-----VFLQKHYQ 554
+V + LD ++ S +EA T+ + V + D+ F+ +Y+
Sbjct: 874 TGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYR 933
Query: 555 MEILENFTVDCEILQVQAVYKNSKKSNKIAYGF--HLGDNIIRDTFRISRNTGSIKLKRK 728
+++ E+ I+ ++A + +S ++ Y H N F + + +G++++ ++
Sbjct: 934 VKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN-----FDVDKLSGAVRIVQQ 988
Query: 729 LLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 848
L + +Q Y V A P+ + V + V D+N+N
Sbjct: 989 LDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNEN 1028
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Frame = +3
Query: 534 FLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLG---DNIIRDTFRISRNT 704
F + Y + E+ V EI ++A + S + Y G ++ ++F I R +
Sbjct: 2705 FSEPFYTFTVSEDVPVGTEIDLIRAEH-----SGTVLYSLVKGNTPESNRDESFVIDRQS 2759
Query: 705 GSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
G +KL++ L + + Y+F + A D A +VSI VKD NDNS V
Sbjct: 2760 GRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPV 2810
Score = 38.1 bits (87), Expect = 0.033
Identities = 57/232 (24%), Positives = 102/232 (43%), Gaps = 17/232 (7%)
Frame = +3
Query: 240 PRFF-EPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFE--EPTGIFKLDQKKF 410
PRF E YK T V E+ G I + DAD + N+ YF +P G F ++ +
Sbjct: 2918 PRFTAEIYKGT-VSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQ- 2975
Query: 411 PSIRLIVQKHLDYNVKSVFSASLEACS---TQTLEIHVQVTDL-----VFLQKHYQMEIL 566
++ V+K LD + + ++ A + + V+V D V + Y I
Sbjct: 2976 NEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIP 3035
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
E+ I+Q+ A + + + +I Y LG + F+++ +TG +K L + +
Sbjct: 3036 EDVLPGKLIMQISATDADIRSNAEITYTL-LGSG--AEKFKLNPDTGELKTSTPLDREEQ 3092
Query: 747 QKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS------SVIVTIFGNSK 884
Y V A D A++ +T++D+NDN+ +T+F N++
Sbjct: 3093 AVYHLLVRAT---DGGGRFCQASIVVTLEDVNDNAPEFSADPYAITVFENTE 3141
Score = 31.6 bits (70), Expect = 3.1
Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 13/196 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQIT-------------EYFFEEPT 380
P F + EN+ IG+ I A D D N +T ++F +
Sbjct: 461 PEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVS 520
Query: 381 GIFKLDQKKFPSIRLIVQKHLDYNVKSVFSASLEACSTQTLEIHVQVTDLVFLQKHYQME 560
LD + P + + + D+ + + +E +T TL T L F + + +
Sbjct: 521 TSENLDYELMPRVYTLRIRASDWGLP--YRREVEVLATITLNNLNDNTPL-FEKINCEGT 577
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAK 740
I + V +I V A+ ++ + + Y G+ + D F ++ N+G + LKR L+
Sbjct: 578 IPRDLGVGEQITTVSAI--DADELQLVQYQIEAGNEL--DLFSLNPNSGVLSLKRSLMDG 633
Query: 741 FRQKYKFRVYAVYLMD 788
K F + D
Sbjct: 634 LGAKVSFHSLRITATD 649
>sp|Q9Y5G2|PCDGE_HUMAN Protocadherin gamma B2 precursor (PCDH-gamma-B2)
Length = 931
Score = 63.5 bits (153), Expect = 7e-10
Identities = 63/223 (28%), Positives = 102/223 (45%), Gaps = 17/223 (7%)
Frame = +3
Query: 249 FEPYKVTL-VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSIR- 422
F+ K+ L + E+ G+ L+PA D+DV PN+ + Y + F L +K+ P R
Sbjct: 133 FKQTKINLKIGESTKPGTTFPLDPALDSDVGPNS-LQRYHLND-NEYFDLAEKQTPDGRK 190
Query: 423 ---LIVQKHLDYNVKSVFSASLEACS------TQTLEIHVQVTDL-----VFLQKHYQME 560
LI++ LD S+ L A + T +I ++VTD VF Q Y++
Sbjct: 191 YPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVT 250
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAK 740
+ E+ +LQV A ++ + +I Y FH D ++ F ++ TG I K L +
Sbjct: 251 LREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFE 310
Query: 741 FRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS-SVIVT 866
Y + A DP A ++ + + D ND + VIVT
Sbjct: 311 IASSYTLSIEA---KDPGDLAAHCSIQVEILDDNDCAPEVIVT 350
>sp|Q9NYQ6|CELR1_HUMAN Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo
homolog 2) (hFmi2)
Length = 3014
Score = 63.2 bits (152), Expect = 1e-09
Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 11/215 (5%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F + V E+ +G+ I A D D N +IT Y ++P F++D S
Sbjct: 787 PVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARIT-YVIQDPVPQFRIDPD---SG 842
Query: 420 RLIVQKHLDYNVKSVFSASLEA--------CSTQTLEIHV-QVTDLV--FLQKHYQMEIL 566
+ LDY + ++ ++ A T TLEI + D FL YQ I
Sbjct: 843 TMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIF 902
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
E+ ILQV A ++S + ++ Y F GD+ D F I +G I+ +R+L +
Sbjct: 903 EDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGD-FYIEPTSGVIRTQRRLDRENV 961
Query: 747 QKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS 851
Y AV P A + +T+ DINDN+
Sbjct: 962 AVYNLWALAVDRGSPTPLSASVEIQVTILDINDNA 996
Score = 48.1 bits (113), Expect = 3e-05
Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 37/244 (15%)
Frame = +3
Query: 237 WPRFFEPYKVTLVPENISIGSFICLEPAYDADVDPN----------NQITEYFFEEPTGI 386
+P+F E V VPE++ + + + A D D N N +++ +GI
Sbjct: 456 YPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGI 515
Query: 387 FKLDQKKFPSIRLIVQKHLDYNVKSVFSASLEACS-------TQTLEIHVQVTDL----- 530
L V LD+ +S S++A + + VQV D+
Sbjct: 516 ------------LDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEP 563
Query: 531 VFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAY-----------GFHLGDNIIR 677
+F+ +Q +LEN + ++ +QAV +S ++ ++ Y G G
Sbjct: 564 IFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPA 623
Query: 678 DT----FRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDIND 845
T F+I ++G I + +L + + Y F V AV P + + +VSITV D+ND
Sbjct: 624 PTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSS-TSVSITVLDVND 682
Query: 846 NSSV 857
N V
Sbjct: 683 NDPV 686
Score = 45.1 bits (105), Expect = 3e-04
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Frame = +3
Query: 528 LVFLQKHYQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFH-LGDNIIRDTFRISRNT 704
L F +YQ+ + EN ILQ+ A Y + +++Y L D R FRI T
Sbjct: 243 LKFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSAT 302
Query: 705 GSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
G++ L + ++ + RV AV P A +++ VKD ND+S V
Sbjct: 303 GAVSTDSVLDRETKETHVLRVKAVDYSTPP-RSATTYITVLVKDTNDHSPV 352
Score = 40.8 bits (94), Expect = 0.005
Identities = 43/208 (20%), Positives = 92/208 (44%), Gaps = 10/208 (4%)
Frame = +3
Query: 273 VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKK-FPSIRLIVQKHLDY 449
V EN+ +G + A D D N + +F+L++ S R ++ +
Sbjct: 362 VRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAA 421
Query: 450 NVKSVFSASLEACS----TQTLEIHVQVTDL-----VFLQKHYQMEILENFTVDCEILQV 602
+ + A+ + + + T ++++V D F +++Y +++ E+ ++ +L+V
Sbjct: 422 EYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRV 481
Query: 603 QAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYL 782
QA ++ ++ I Y G+ + F + +G + + L + QKY + A
Sbjct: 482 QATDRDQGQNAAIHYSILSGN--VAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDG 539
Query: 783 MDPMLPKAVANVSITVKDINDNSSVIVT 866
P L + VS+ V D+NDN + V+
Sbjct: 540 GRPPLINSSGVVSVQVLDVNDNEPIFVS 567
>sp|Q9HCU4|CELR2_HUMAN Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal
growth factor-like 2) (Multiple epidermal growth
factor-like domains 3) (Flamingo 1)
Length = 2923
Score = 62.4 bits (150), Expect = 2e-09
Identities = 59/219 (26%), Positives = 100/219 (45%), Gaps = 13/219 (5%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F + V E+ G+ + L A D D N +IT YF E+ F++D +
Sbjct: 710 PVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARIT-YFMEDSIPQFRIDAD---TG 765
Query: 420 RLIVQKHLDYNVKSVFSASLEACS------TQTLEIHVQVTDL-----VFLQKHYQMEIL 566
+ Q LDY + ++ ++ A + T + + V D+ FL+ YQ +
Sbjct: 766 AVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVY 825
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
E+ +LQ+ A ++S + ++ Y F GD+ D F + +G ++ R+L +
Sbjct: 826 EDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGD-FIVESTSGIVRTLRRLDRENV 884
Query: 747 QKYKFRVYAVYLMDPMLPKA--VANVSITVKDINDNSSV 857
+Y R YAV D +P A V++TV D+NDN V
Sbjct: 885 AQYVLRAYAV---DKGMPPARTPMEVTVTVLDVNDNPPV 920
Score = 49.7 bits (117), Expect = 1e-05
Identities = 52/222 (23%), Positives = 95/222 (42%), Gaps = 17/222 (7%)
Frame = +3
Query: 252 EPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFE----EPTGIFKLDQKKFPSI 419
+ YK +L EN+ +G + A D D PN I E P+ +F++D + S
Sbjct: 292 QEYKESL-RENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPR---SG 347
Query: 420 RLIVQKHLDYNVKSVFSASLEACS--------TQTLEIHVQVTD-----LVFLQKHYQME 560
+ + +D + ++EA + T + + V D F +K Y ++
Sbjct: 348 VIRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQ 407
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAK 740
+ E+ T +L+V A ++ + + Y G+ R F + TG++ + L +
Sbjct: 408 VREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGN--ARGQFYLDAQTGALDVVSPLDYE 465
Query: 741 FRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSVIVT 866
++Y RV A P L V++ V DINDN+ + V+
Sbjct: 466 TTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVS 507
Score = 47.0 bits (110), Expect = 7e-05
Identities = 59/219 (26%), Positives = 98/219 (44%), Gaps = 15/219 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPT--GIFKLDQKKFP 413
P+F E V V E+++ G+ + A D D +N + Y G F LD +
Sbjct: 397 PQFSEKRYVVQVREDVTPGAPVLRVTASDRDKG-SNAVVHYSIMSGNARGQFYLDAQ--- 452
Query: 414 SIRLIVQKHLDYNVKSVFSASLEA-------CSTQTLEIHVQVTDL-----VFLQKHYQM 557
+ L V LDY ++ + A S + + VQV D+ +F+ +Q
Sbjct: 453 TGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQA 512
Query: 558 EILENFTVDCEILQVQAVYKNSKKSNKIAYGFH-LGDNIIRDTFRISRNTGSIKLKRKLL 734
+LE+ + +L VQA+ ++ + ++ Y +G + F I+ TG I + +L
Sbjct: 513 TVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDF---PFTINNGTGWISVAAELD 569
Query: 735 AKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNS 851
+ Y F V A P L A A+VS+TV D+NDN+
Sbjct: 570 REEVDFYSFGVEARDHGTPALT-ASASVSVTVLDVNDNN 607
>sp|O35161|CELR1_MOUSE Cadherin EGF LAG seven-pass G-type receptor 1 precursor
Length = 3034
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/217 (25%), Positives = 94/217 (43%), Gaps = 11/217 (5%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F + V E+ +G+ I A D D N +IT Y E+P F++D +
Sbjct: 802 PVFQSSHYTVSVSEDRPVGTSIATISATDEDTGENARIT-YVLEDPVPQFRIDPD---TG 857
Query: 420 RLIVQKHLDYNVKSVFSASLEACS------TQTLEIHVQVTDLV-----FLQKHYQMEIL 566
+ LDY ++ ++ ++ A + T + + + D FL+ YQ +
Sbjct: 858 TIYTMTELDYEDQAAYTLAITAQDNGIPQKSDTTSLEILILDANDNAPRFLRDFYQGSVF 917
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
E+ +LQV A ++S + ++ Y F GD+ D F I +G I+ +R+L +
Sbjct: 918 EDAPPSTSVLQVSATDRDSGPNGRLLYTFQGGDDGDGD-FYIEPTSGVIRTQRRLDRENV 976
Query: 747 QKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
Y AV P A + ++V DINDN V
Sbjct: 977 AVYNLWALAVDRGSPNPLSASVGIQVSVLDINDNPPV 1013
Score = 53.1 bits (126), Expect = 1e-06
Identities = 47/208 (22%), Positives = 94/208 (45%), Gaps = 10/208 (4%)
Frame = +3
Query: 273 VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKK-FPSIRLIVQKHLDY 449
+ EN+ +G + A D D N + E G+F++D + R +V +
Sbjct: 377 IRENLEVGYEVLTIRATDGDAPSNANMRYRLLEGAGGVFEIDARSGVVRTRAVVDREEAA 436
Query: 450 NVKSVFSASLEACSTQTLE----IHVQVTDL-----VFLQKHYQMEILENFTVDCEILQV 602
+ + A+ + + L +H+ V D F +K Y +++ E+ V+ +L+V
Sbjct: 437 EYQLLVEANDQGRNPGPLSASATVHIVVEDENDNYPQFSEKRYVVQVPEDVAVNTAVLRV 496
Query: 603 QAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFRQKYKFRVYAVYL 782
QA ++ ++ I Y G+ ++ F + +GS+ + L + ++Y R+ A
Sbjct: 497 QATDRDQGQNAAIHYSIVSGN--LKGQFYLHSLSGSLDVINPLDFEAIREYTLRIKAQDG 554
Query: 783 MDPMLPKAVANVSITVKDINDNSSVIVT 866
P L + VS+ V D+NDN+ + V+
Sbjct: 555 GRPPLINSSGLVSVQVLDVNDNAPIFVS 582
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/233 (23%), Positives = 100/233 (42%), Gaps = 29/233 (12%)
Frame = +3
Query: 237 WPRFFEPYKVTLVPENISIGSFICLEPAYDADVDPN----------NQITEYFFEEPTG- 383
+P+F E V VPE++++ + + A D D N N +++ +G
Sbjct: 471 YPQFSEKRYVVQVPEDVAVNTAVLRVQATDRDQGQNAAIHYSIVSGNLKGQFYLHSLSGS 530
Query: 384 ---IFKLDQKKFPSIRLIVQKHLDYNVKSVFSASLEACSTQTLEIHVQVTDLVFLQKHYQ 554
I LD + L ++ + S+ L S Q L+++ +F+ +Q
Sbjct: 531 LDVINPLDFEAIREYTLRIKAQDGGRPPLINSSGL--VSVQVLDVNDNAP--IFVSSPFQ 586
Query: 555 MEILENFTVDCEILQVQAVYKNSKKSNKIAYGF-HLGDNIIRDT--------------FR 689
+LEN + +L +QAV ++ ++ ++ Y I+ + F+
Sbjct: 587 AAVLENVPLGHSVLHIQAVDADAGENARLQYRLVDTASTIVGGSSVDSENPASAPDFPFQ 646
Query: 690 ISRNTGSIKLKRKLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 848
I ++G I + +L + + Y F V AV P + + A+VSITV D+NDN
Sbjct: 647 IHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPAMSSS-ASVSITVLDVNDN 698
Score = 33.9 bits (76), Expect = 0.63
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Frame = +3
Query: 549 YQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFH-LGDNIIRDTFRISRNTGSIKLKR 725
YQ+ + EN +++++A + + +++Y L D F I TG++ R
Sbjct: 265 YQVSVPENEPAGTAVIELRAHDPDEGDAGRLSYQMEALFDERSNGYFLIDAATGAVTTAR 324
Query: 726 KLLAKFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
L + + + +V AV P A +++TV D ND+S V
Sbjct: 325 SLDRETKDTHVLKVSAVDHGSPRR-SAATYLTVTVSDTNDHSPV 367
Score = 31.2 bits (69), Expect = 4.1
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Frame = +3
Query: 240 PRFFEPYKVTL-VPENISIGSFICLEPAYDADVDPNNQITEYFFE-EPTGIFKLDQKKFP 413
P FE ++ L V EN +GS + A D D PN QI E +F+LD
Sbjct: 1011 PPVFEKDELELFVEENSPVGSVVARIRANDPDEGPNAQIIYQIVEGNVPEVFQLDLLS-G 1069
Query: 414 SIRLIVQKHLDYNVKSVFSASLEACSTQTLE---IHVQVTD 527
+R +V+ LD+ V+ + ++A S + +H+++ D
Sbjct: 1070 DLRALVE--LDFEVRRDYMLVVQATSAPLVSRATVHIRLLD 1108
>sp|Q91ZI0|CELR3_MOUSE Cadherin EGF LAG seven-pass G-type receptor 3 precursor
Length = 3301
Score = 61.6 bits (148), Expect = 3e-09
Identities = 55/217 (25%), Positives = 100/217 (46%), Gaps = 11/217 (5%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSI 419
P F + + E+ +GS + + A D DV N +IT Y E+ F++D S
Sbjct: 847 PVFQSAHYSVSMNEDRPVGSTVVVISASDDDVGENARIT-YLLEDNLPQFRIDAD---SG 902
Query: 420 RLIVQKHLDYNVKSVFSASLEACST------QTLEIHVQVTDL-----VFLQKHYQMEIL 566
+ +Q LDY + ++ ++ A T + V V D+ F+ HY +
Sbjct: 903 AITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVS 962
Query: 567 ENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKLLAKFR 746
E+ +LQ+ A +++ + ++ Y F G++ D F I +G ++ R+L +
Sbjct: 963 EDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGD-FTIEPTSGIVRTVRRLDREAV 1021
Query: 747 QKYKFRVYAVYLMDPMLPKAVANVSITVKDINDNSSV 857
Y+ YAV P L + ++ +TV+D+NDN+ V
Sbjct: 1022 PVYELTAYAVDRGVPPL-RTPVSIQVTVQDVNDNAPV 1057
Score = 50.1 bits (118), Expect = 8e-06
Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 14/217 (6%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDPNNQITEYFFE-EPTGIFKLDQKKFPS 416
P+F E V V E++ + + A D D D N + G F +D +
Sbjct: 534 PQFGEKRYVAQVREDVRPHTVVLRVTATDKDKDANGLVHYNIISGNSRGHFAIDSL---T 590
Query: 417 IRLIVQKHLDYNVKSVFSASLEA-------CSTQTLEIHVQVTDL-----VFLQKHYQME 560
+ V LD+ + ++ + A S T +QV D+ +F+ +Q+
Sbjct: 591 GEIQVMAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHAPIFVSTPFQVS 650
Query: 561 ILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDT-FRISRNTGSIKLKRKLLA 737
+LEN + ++ +QAV + +++++ Y + DT F I+ TG + + L
Sbjct: 651 VLENAPLGHSVIHIQAVDADHGENSRLEYSL---TGVASDTPFVINSATGWVSVSGPLDR 707
Query: 738 KFRQKYKFRVYAVYLMDPMLPKAVANVSITVKDINDN 848
+ + Y F V A P L A A+V++TV D+NDN
Sbjct: 708 ESVEHYFFGVEARDHGSPPL-SASASVTVTVLDVNDN 743
Score = 37.7 bits (86), Expect = 0.044
Identities = 55/226 (24%), Positives = 92/226 (40%), Gaps = 22/226 (9%)
Frame = +3
Query: 240 PRFFEPYKVTLVPENISIGSFICLEPAYDADVDP------------NNQITEYFFEEP-T 380
P+F + TLVPEN + G+ + A D D N++ E F +P +
Sbjct: 314 PQFPQYNYQTLVPENEAAGTSVLRVVAQDPDPGEAGRLIYSLAALMNSRSLELFSIDPQS 373
Query: 381 GIFK----LDQKKFPSIRLIVQKHLDYNVKSVFSASLEACSTQTLEIHVQVTDLVFLQKH 548
G+ + LD++ L V D+ + + ++ A + H VF Q
Sbjct: 374 GLIRTAAALDRESMERHYLRVTAQ-DHGSPRLSATTMVAVTVADRNDHAP----VFEQAQ 428
Query: 549 YQMEILENFTVDCEILQVQAVYKNSKKSNKIAYGFHLGDNIIRD----TFRISRNTGSIK 716
Y+ + EN ILQ++A ++ + + Y F +G +R F I +G I
Sbjct: 429 YRETLRENVEEGYPILQLRATDGDAPPNANLRYRF-VGSPAVRTAAAAAFEIDPRSGLIS 487
Query: 717 LKRKLLAKFRQKYKFRVYAV-YLMDPMLPKAVANVSITVKDINDNS 851
++ + + Y+ V A +P A V ITV D NDN+
Sbjct: 488 TSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNA 533
Score = 31.6 bits (70), Expect = 3.1
Identities = 41/169 (24%), Positives = 66/169 (39%), Gaps = 16/169 (9%)
Frame = +3
Query: 273 VPENISIGSFICLEPAYDADVDPNNQITEYFFEEPTGIFKLDQKKFPSIRLIVQKHLDYN 452
V EN +GS + A D D PN I E I +L Q S L LDY
Sbjct: 1067 VKENSIVGSVVAQITAVDPDDGPNAHIMYQIVE--GNIPELFQMDIFSGELTALIDLDYE 1124
Query: 453 VKSVFSASLEACSTQTLE---IHVQVTDLVFLQKHYQMEILENF-------------TVD 584
+ + ++A S + +HV++ D ++ +L NF T
Sbjct: 1125 ARQEYVIVVQATSAPLVSRATVHVRLVD-----QNDNSPVLNNFQILFNNYVSNRSDTFP 1179
Query: 585 CEILQVQAVYKNSKKSNKIAYGFHLGDNIIRDTFRISRNTGSIKLKRKL 731
I+ Y + S+ + Y F G+ + ++R +G ++L RKL
Sbjct: 1180 SGIIGRIPAY-DPDVSDHLFYSFERGNEL--QLLVVNRTSGELRLSRKL 1225
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,217,654
Number of Sequences: 369166
Number of extensions: 1748187
Number of successful extensions: 4696
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4038
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4555
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)