Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_001_D14 (858 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8K9B9|SYL_BUCAP Leucyl-tRNA synthetase (Leucine--tRNA l... 37 0.092 sp|Q7VLK4|SSPA_HAEDU Stringent starvation protein A homolog 32 3.0 sp|P59057|SYFB_BUCAP Phenylalanyl-tRNA synthetase beta chai... 31 3.9 sp|O70167|P3C2G_MOUSE Phosphatidylinositol-4-phosphate 3-ki... 31 5.0 sp|Q7V0W1|SYC_PROMP Cysteinyl-tRNA synthetase (Cysteine--tR... 30 8.6 sp|O15078|CE29_HUMAN Centrosomal protein Cep290 30 8.6 sp|Q64654|CP51A_RAT Cytochrome P450 51A1 (CYPLI) (P450LI) (... 30 8.6 sp|P59523|UPPP_BUCBP Undecaprenyl-diphosphatase (Undecapren... 30 8.6
>sp|Q8K9B9|SYL_BUCAP Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS) Length = 861 Score = 36.6 bits (83), Expect = 0.092 Identities = 44/205 (21%), Positives = 83/205 (40%), Gaps = 2/205 (0%) Frame = -3 Query: 658 IQKKLIGKEQSMNILTQKAKEQMFFLHNERHFSVDDLLENFPSTRKSCEYVVTRPLPILS 479 I+ K I K+ + +IL +K K+ LH DD+ RKS ++ + +++ Sbjct: 682 IEVKKINKKVNFDILNKKQKKMYCLLHKTIIKVSDDI-----GRRKSFNTAISSIMELVN 736 Query: 478 LVELIRFNERIINRLIQVKSLSIKNKLDRYEQFLWIVEQNMYSLIQYANGNDKFEYPNKS 299 + + + +I+ +SI L + + L QY N N +Y Sbjct: 737 ELSIFKIENEEDKSIIKESLMSIIKMLYPFTPHF------CFRLWQYLNKNCCIDYETWP 790 Query: 298 LLQLHDENEAKRIPGEMETLYNFTVLGKSFKCLPSSEKKPLILEKQNHQLETLLLYFKPE 119 E K + + TL + + KK +E +NH + +L + Sbjct: 791 TF------EKKILSSDKNTLI-----------IQINGKKQCAIEVKNHLNKEEILSYIEN 833 Query: 118 SDIIRERLNTKKIIK--FIPKQLPN 50 II++++ KIIK +IP+++ N Sbjct: 834 QSIIQKKIKNLKIIKIIYIPQKVIN 858
>sp|Q7VLK4|SSPA_HAEDU Stringent starvation protein A homolog Length = 214 Score = 31.6 bits (70), Expect = 3.0 Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 14/104 (13%) Frame = -3 Query: 547 LENFPSTRKSCEYVVTRP---LPILSLVELIRFNERIINRLIQVKS-----------LSI 410 LEN S +++ P +P L +L+ FN RII + + L Sbjct: 38 LENINPNTISEDFLELNPYANIPTLVDRDLVLFNSRIIMEYLDERFPHPPLMPVYPVLRG 97 Query: 409 KNKLDRYEQFLWIVEQNMYSLIQYANGNDKFEYPNKSLLQLHDE 278 K++L + +EQ+ YSLI N N + + K+L QL +E Sbjct: 98 KSRLTMHR-----IEQDWYSLIDIVNKNPESKEAKKALSQLREE 136
>sp|P59057|SYFB_BUCAP Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS) Length = 798 Score = 31.2 bits (69), Expect = 3.9 Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 5/126 (3%) Frame = -3 Query: 415 SIKNKLDRYEQFLWIVEQNMYSLIQYANGNDKFEYPNKSLLQLHDENEAKRIPGEMETLY 236 S++ K+D Y+ ++ ++ SL++ G +KFE ++++L LH E AK ++ Y Sbjct: 610 SVRRKVDFYD-----LKGDLESLLEVICGLNKFEIRHQNILGLHPEQSAKIY---LDNKY 661 Query: 235 NFTVLGKSFKCLPSSEKKPLILEKQNHQLETLLLY-----FKPESDIIRERLNTKKIIKF 71 +G K P EKK L L E L Y F +I + + + I Sbjct: 662 ----IGSLGKIHPKIEKK-LNLYNSTFLFELSLNYISKLKFYNTEEISKYPTSRRDIAIL 716 Query: 70 IPKQLP 53 + K +P Sbjct: 717 VSKDIP 722
>sp|O70167|P3C2G_MOUSE Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma) Length = 1506 Score = 30.8 bits (68), Expect = 5.0 Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 13/136 (9%) Frame = -3 Query: 457 NERIINRLIQVKSLSIKNKLDRYEQFLWIVEQNMYSLIQYANGNDKFEYPNKSLLQLH-- 284 N + + + ++ L L E L + + + ++ G+ K NKS++QLH Sbjct: 308 NYLVKDLIAEILLLCANEPLSPKEYLLSVCGSEEFLQMDHSLGSHKIFQKNKSVIQLHLQ 367 Query: 283 ----------DENEAKRIPGEMETLYNFTVLGK-SFKCLPSSEKKPLILEKQNHQLETLL 137 ++E P + L FT + K S +CL + +++K N +E LL Sbjct: 368 KNRDTPGKLSRKSEDDHSPFHLNQLLEFTHIWKISRQCLST------VMKKYNLHVEHLL 421 Query: 136 LYFKPESDIIRERLNT 89 KP+ D+ + L++ Sbjct: 422 ---KPQKDMEEKHLSS 434
>sp|Q7V0W1|SYC_PROMP Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase) (CysRS) Length = 492 Score = 30.0 bits (66), Expect = 8.6 Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 2/122 (1%) Frame = -3 Query: 370 VEQNMYSLIQYANGNDKFEYPNKSLLQLHDENEAKRIPGEMETLYNFTVLGKSFKCLPSS 191 VE+ +I Y K ++ N L+ I + L NF + K L + Sbjct: 348 VEETYKDMINYEISQKKIKFTNALNNDLNTAGAIAIIYELAKPLKNFINQFQRIKNLEIN 407 Query: 190 EKKPLILEKQNHQLETL--LLYFKPESDIIRERLNTKKIIKFIPKQLPNIANVDYSNLFK 17 + L + LE L +L K E II R+N +I+ I K+L DY+ K Sbjct: 408 TNEKFHLRETFKTLEELTDVLGLKKEEIIIDNRINEDQILSLINKRLGAKKEKDYAEADK 467 Query: 16 YK 11 + Sbjct: 468 IR 469
>sp|O15078|CE29_HUMAN Centrosomal protein Cep290 Length = 1539 Score = 30.0 bits (66), Expect = 8.6 Identities = 36/156 (23%), Positives = 67/156 (42%), Gaps = 2/156 (1%) Frame = -3 Query: 655 QKKLIGKEQSMNILTQKAKEQMFFLHNERHFSVDDLLENFPSTRKSCEYVVTRPLPILSL 476 Q+ L + + +K +E + LH+ D L F T + + + P P+ + Sbjct: 620 QRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQT--AWDLMKQSPTPVPTN 677 Query: 475 VELIRFNERIINRLIQVKSLSIKNKLDRYEQFLWIVEQNMYSLIQYANGNDKFEYPN-KS 299 IR E + + + + S+ + L + ++ V Q++ + K E+ N K Sbjct: 678 KHFIRLAE--MEQTVAEQDDSLSSLLVKLKK----VSQDLERQREITELKVK-EFENIKL 730 Query: 298 LLQLHDENEAKRIPGEMETL-YNFTVLGKSFKCLPS 194 LQ + E+E K++ E+E L Y K +CL S Sbjct: 731 QLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKS 766
>sp|Q64654|CP51A_RAT Cytochrome P450 51A1 (CYPLI) (P450LI) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 30.0 bits (66), Expect = 8.6 Identities = 19/79 (24%), Positives = 35/79 (44%) Frame = -3 Query: 241 LYNFTVLGKSFKCLPSSEKKPLILEKQNHQLETLLLYFKPESDIIRERLNTKKIIKFIPK 62 +++FT++GK+F L S+ L+ +N L +Y RL T K + Sbjct: 95 VFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVY---------GRLTTPVFGKGVAY 145 Query: 61 QLPNIANVDYSNLFKYKIN 5 +PN ++ + K +N Sbjct: 146 DVPNAVFLEQKKILKSGLN 164
>sp|P59523|UPPP_BUCBP Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein) Length = 268 Score = 30.0 bits (66), Expect = 8.6 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Frame = -1 Query: 390 MNNFYGL-LNKICIL*FNMQMVMINSNIPINHCCNYMTKMKLREFLV 253 +NNFY + +N I +L I SNI I C N M L F++ Sbjct: 207 INNFYDISINNIPMLFSGFLSAFITSNIVIKRCLNTMKNCSLIPFII 253
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,376,588 Number of Sequences: 369166 Number of extensions: 1462422 Number of successful extensions: 4087 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 3960 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4083 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8486520240 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)