Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_D06
(875 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8NFW9|MYRIP_HUMAN Rab effector MyRIP (Myosin-VIIa- and ... 62 2e-09
sp|Q8TDW5|SYTL5_HUMAN Synaptotagmin-like protein 5 60 6e-09
sp|Q9Y2J0|RP3A_HUMAN Rabphilin-3A (Exophilin-1) 59 1e-08
sp|Q8K3I4|MYRIP_MOUSE Rab effector MyRIP (Myosin-VIIa- and ... 59 2e-08
sp|Q06846|RP3A_BOVIN Rabphilin-3A (Exophilin-1) 58 3e-08
sp|P47709|RP3A_RAT Rabphilin-3A (Exophilin-1) 57 7e-08
sp|P47708|RP3A_MOUSE Rabphilin-3A (Exophilin-1) 57 9e-08
sp|Q80T23|SYTL5_MOUSE Synaptotagmin-like protein 5 56 1e-07
sp|Q96C24|SYTL4_HUMAN Synaptotagmin-like protein 4 (Exophil... 56 1e-07
sp|Q8VHQ7|SYTL4_RAT Synaptotagmin-like protein 4 (Exophilin... 54 4e-07
>sp|Q8NFW9|MYRIP_HUMAN Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein)
(Exophilin-8) (Slp homolog lacking C2 domains-c)
Length = 859
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEI--KGELKSSTKKQANISKTNC 226
L++S L + E +LQV++R+ L E RLS + ++ +G S K + C
Sbjct: 5 LDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLDEEGSKCSILSKHQQFVEHCC 64
Query: 227 LYCSSN----LNDFDGCEKCQKNVCMKCCKSFGTQNVKLCKICYQEMLLEAKKAKWFYEN 394
+ C S +N C C+ NVC CC + +C +C Q LL A+ +WFY N
Sbjct: 65 MRCCSPFTFLVNTKRQCGDCKFNVCKSCCSYQKHEKAWVCCVCQQARLLRAQSLEWFYNN 124
Query: 395 I 397
+
Sbjct: 125 V 125
>sp|Q8TDW5|SYTL5_HUMAN Synaptotagmin-like protein 5
Length = 730
Score = 60.5 bits (145), Expect = 6e-09
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLY 232
+N+S L +HEK ++L VL+R+ L E+ R+ ++ NE+ + S K Q S+ C++
Sbjct: 8 INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRV-CVH 66
Query: 233 CSSNL----NDFDGCEKCQKNVCMKCCKSFGTQNVKLCKICYQEMLLEAKKAKWFYE 391
C NL + D C+ C VC + C+ G C +C + L +WF+E
Sbjct: 67 CHRNLGLIFDRGDPCQACSLRVCRE-CRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
>sp|Q9Y2J0|RP3A_HUMAN Rabphilin-3A (Exophilin-1)
Length = 694
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 6/118 (5%)
Frame = +2
Query: 68 LNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLYCSSNL 247
L + EK I+ +V+ R K+ + E R+ R+ + L++ K A C+ C L
Sbjct: 50 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDR----LENMRKNVAGDGVNRCILCGEQL 105
Query: 248 NDFDG----CEKCQKNVCMKCCKSFGTQ--NVKLCKICYQEMLLEAKKAKWFYENIPQ 403
CE C+KNVC KC + +V LCKIC ++ + + WF++ P+
Sbjct: 106 GMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPK 163
>sp|Q8K3I4|MYRIP_MOUSE Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein)
(Exophilin-8) (Slp homolog lacking C2 domains-c)
Length = 856
Score = 58.9 bits (141), Expect = 2e-08
Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELK--SSTKKQANISKTNC 226
L++S L + E +LQV++R+ L E RLS M + E S K + C
Sbjct: 5 LDLSGLTDDETEHVLQVVQRDFNLRKKEEDRLSEMKQRLAEENSKCSILSKHQKFVERCC 64
Query: 227 LYCSSN----LNDFDGCEKCQKNVCMKCCKSFGTQNVKLCKICYQEMLLEAKKAKWFYEN 394
+ C S +N C +C+ +VC CC + + +C +C Q LL + +WFY N
Sbjct: 65 MRCCSPFTFLVNARRRCGECKFSVCKSCCSYQKHEKLWVCCVCQQARLLRTQSLEWFYNN 124
Query: 395 I 397
+
Sbjct: 125 V 125
>sp|Q06846|RP3A_BOVIN Rabphilin-3A (Exophilin-1)
Length = 704
Score = 58.2 bits (139), Expect = 3e-08
Identities = 36/121 (29%), Positives = 56/121 (46%), Gaps = 9/121 (7%)
Frame = +2
Query: 68 LNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLYCSSNL 247
L + EK I+ +V+ R K+ + E R+ R+ + L++ K A C+ C L
Sbjct: 50 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDR----LENMRKNVAGDGVNRCILCGEQL 105
Query: 248 NDFDG----CEKCQKNVCMKCCKSFGTQN-----VKLCKICYQEMLLEAKKAKWFYENIP 400
CE C+KNVC KC T N V LCKIC ++ + + WF++ P
Sbjct: 106 GMLGSACVVCEDCKKNVCTKC--GVETSNNRPHPVWLCKICIEQREVWKRSGAWFFKGFP 163
Query: 401 Q 403
+
Sbjct: 164 K 164
>sp|P47709|RP3A_RAT Rabphilin-3A (Exophilin-1)
Length = 684
Score = 57.0 bits (136), Expect = 7e-08
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Frame = +2
Query: 68 LNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLYCSSNL 247
L + EK I+ +V+ R K+ E R+ R+ + L++ K A C+ C L
Sbjct: 46 LTDEEKEIINRVIARAEKMETMEQERIGRLVDR----LETMRKNVAGDGVNRCILCGEQL 101
Query: 248 NDFDG----CEKCQKNVCMKCCKSFGTQN-----VKLCKICYQEMLLEAKKAKWFYENIP 400
CE C+KNVC KC T N V LCKIC ++ + + WF++ P
Sbjct: 102 GMLGSACVVCEDCKKNVCTKC--GVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFP 159
Query: 401 Q 403
+
Sbjct: 160 K 160
>sp|P47708|RP3A_MOUSE Rabphilin-3A (Exophilin-1)
Length = 681
Score = 56.6 bits (135), Expect = 9e-08
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Frame = +2
Query: 68 LNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLYCSSNL 247
L + EK I+ +V+ R K+ E R+ R+ + L++ K A C+ C L
Sbjct: 46 LTDEEKEIINRVIARAEKMEAMEQERIGRLVDR----LETMRKNVAGDGVNRCILCGEQL 101
Query: 248 NDFDG----CEKCQKNVCMKCCKSFGTQN-----VKLCKICYQEMLLEAKKAKWFYENIP 400
CE C+KNVC KC T N V LCKIC ++ + + WF++ P
Sbjct: 102 GMLGSACVVCEDCKKNVCTKC--GVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFP 159
Query: 401 Q 403
+
Sbjct: 160 K 160
>sp|Q80T23|SYTL5_MOUSE Synaptotagmin-like protein 5
Length = 753
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 4/117 (3%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEIKGELKSSTKKQANISKTNCLY 232
+N+S L +HEK ++L VL+R+ L E+ R+ ++ NE+ + S K S+ C++
Sbjct: 8 INLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTHQEASRV-CVH 66
Query: 233 CSSNL----NDFDGCEKCQKNVCMKCCKSFGTQNVKLCKICYQEMLLEAKKAKWFYE 391
C L + D C+ C VC + C+ G C +C + L +WF E
Sbjct: 67 CHKTLGLIFDRGDPCQACSLRVCSE-CRVTGLDGSWKCTVCAKVAQLRIISGEWFLE 122
>sp|Q96C24|SYTL4_HUMAN Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Length = 671
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEI-KGELKSSTKKQANISKTNCL 229
L++S L+E EK ++L VL+R+ ++ + R+ R+ NE+ + + K + + + S C
Sbjct: 5 LDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCA 64
Query: 230 YCSSNLNDF----DGCEKCQKNVCMKCC--KSFGTQNVKLCKICYQEMLLEAKKAKWFYE 391
C +L + C C VC C +S GT CK+C +E+ L+ WFY+
Sbjct: 65 RCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWR---CKVCAKEIELKKATGDWFYD 121
>sp|Q8VHQ7|SYTL4_RAT Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Length = 672
Score = 54.3 bits (129), Expect = 4e-07
Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 5/118 (4%)
Frame = +2
Query: 53 LNISCLNEHEKTILLQVLERNNKLVDHENVRLSRMDNEI-KGELKSSTKKQANISKTNCL 229
L++S L+E E+ ++L VL+R+ +L + R+ R+ NE+ + + K + + + S C
Sbjct: 5 LDLSFLSEMERDLILSVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCA 64
Query: 230 YCSSNLNDF----DGCEKCQKNVCMKCCKSFGTQNVKLCKICYQEMLLEAKKAKWFYE 391
C L + C C VC +C + + CK+C +E+ L+ WFY+
Sbjct: 65 RCQEGLGRLISKSNTCVGCNHLVCREC-RVLESNGSWRCKVCSKEIELKKATGDWFYD 121
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,921,909
Number of Sequences: 369166
Number of extensions: 1313728
Number of successful extensions: 4529
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4511
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)