Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_A12-1
(308 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinas... 35 0.070
sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 (p... 32 0.46
sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 (p... 32 0.46
sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 ... 32 0.46
sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 ... 32 0.46
sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 (p... 31 0.78
sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 ... 31 0.78
sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 ... 31 0.78
sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 ... 31 0.78
sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 ... 31 0.78
>sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase
kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis
signal-regulating kinase 1) (ASK-1)
Length = 1374
Score = 34.7 bits (78), Expect = 0.070
Identities = 19/49 (38%), Positives = 26/49 (53%)
Frame = +1
Query: 7 EPPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLL 153
EP A MF +G K P + +S ++FI C EP+ R+CA LL
Sbjct: 886 EPQAAMFKVGMFKVHPEIP-ESMSAEAKAFILKCFEPDPDKRACANDLL 933
>sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 (p21-activated kinase 1)
(PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2)
Length = 544
Score = 32.0 bits (71), Expect = 0.46
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 468 PLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQH 517
>sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (p65-PAK)
Length = 544
Score = 32.0 bits (71), Expect = 0.46
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 467 PLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQH 516
>sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (Oligophrenin-3)
sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3)
sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3)
Length = 559
Score = 32.0 bits (71), Expect = 0.46
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 482 PLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQH 531
>sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B)
Length = 559
Score = 32.0 bits (71), Expect = 0.46
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 482 PLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQH 531
>sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (Gamma-PAK) (p62-PAK)
Length = 524
Score = 31.2 bits (69), Expect = 0.78
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 448 PLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQH 497
>sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 (p21-activated kinase 1)
(PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase
PAK-A)
Length = 545
Score = 31.2 bits (69), Expect = 0.78
Identities = 15/50 (30%), Positives = 25/50 (50%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F+ CLE + R AK+LL+H
Sbjct: 469 PLRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQH 518
>sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2)
Length = 524
Score = 31.2 bits (69), Expect = 0.78
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 448 PLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQH 497
>sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase)
Length = 524
Score = 31.2 bits (69), Expect = 0.78
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 448 PLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQH 497
>sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (Gamma-PAK) (p21-activated protein kinase I)
(PAKI)
Length = 524
Score = 31.2 bits (69), Expect = 0.78
Identities = 15/50 (30%), Positives = 26/50 (52%)
Frame = +1
Query: 10 PPAVMFIIGTTKKIEYTPCQPISGAMQSFIDDCLEPEQPNRSCAKKLLKH 159
P +++I T E + +S + F++ CLE + R AK+LL+H
Sbjct: 448 PLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQH 497
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,344,841
Number of Sequences: 369166
Number of extensions: 561217
Number of successful extensions: 1274
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1251
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1273
length of database: 68,354,980
effective HSP length: 71
effective length of database: 55,238,795
effective search space used: 1712402645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)